SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		4 / 7 LEU A 302
TYR A 179
LEU A 268
GLN A 270
 None
 1.06A 1kt3A-3v0tA:
undetectable		 1kt3A-3v0tA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		5 / 9 GLY A   7
LEU A  11
THR A 173
ALA A 174
LEU A 175
 None
 0.98A 2npnA-3v0tA:
undetectable		 2npnA-3v0tA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		4 / 7 TYR A 119
VAL A 117
ILE A  79
ASP A 121
 None
 1.24A 2x45C-3v0tA:
undetectable		 2x45C-3v0tA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		4 / 7 TYR A 119
VAL A 117
ILE A  79
ASP A 121
 None
 1.16A 3bu1A-3v0tA:
undetectable		 3bu1A-3v0tA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		4 / 5 GLY A  22
THR A 281
ILE A  40
VAL A  39
 None
ATR  A 338 (-3.0A)
None
None
 0.91A 3wriA-3v0tA:
undetectable		 3wriA-3v0tA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		4 / 5 GLY A  22
THR A 281
ILE A  40
VAL A  39
 None
ATR  A 338 (-3.0A)
None
None
 0.90A 3wriB-3v0tA:
undetectable		 3wriB-3v0tA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		5 / 6 GLY A  99
VAL A 132
PRO A 101
GLY A 139
GLU A 135
 None
 1.30A 4dxuA-3v0tA:
undetectable		 4dxuA-3v0tA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		3 / 3 LEU A 112
VAL A  81
ASP A 121
 None
 0.68A 4y8wC-3v0tA:
undetectable		 4y8wC-3v0tA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		5 / 10 LEU A 181
LEU A 264
ALA A 263
LEU A 293
ALA A 292
 None
 1.11A 4zbrA-3v0tA:
undetectable		 4zbrA-3v0tA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 3v0t PERAKINE REDUCTASE
(Rauvolfia
serpentina) 		5 / 12 PHE A  50
LEU A 175
VAL A 202
GLN A 176
SER A 156
 None
 1.45A 5l8oB-3v0tA:
undetectable		 5l8oB-3v0tA:
18.49