SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v2g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		6 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.21A 1kiaA-3v2gA:
7.5		 1kiaA-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
GLY A 211
 None
 1.14A 1kiaB-3v2gA:
7.5		 1kiaB-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
GLY A 211
 None
 1.14A 1kiaC-3v2gA:
7.3		 1kiaC-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
 None
 1.21A 1nbhA-3v2gA:
7.5		 1nbhA-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		6 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.23A 1nbhB-3v2gA:
7.1		 1nbhB-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
 None
 1.22A 1nbhC-3v2gA:
6.5		 1nbhC-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
 None
 1.22A 1nbhD-3v2gA:
7.1		 1nbhD-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		6 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.24A 1nbiA-3v2gA:
7.4		 1nbiA-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		6 / 12 TYR A 180
ILE A  43
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.23A 1nbiB-3v2gA:
7.4		 1nbiB-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.19A 1nbiC-3v2gA:
6.5		 1nbiC-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 TYR A 180
GLY A 165
ALA A 185
SER A 183
GLY A 211
 None
 1.18A 1nbiD-3v2gA:
6.5		 1nbiD-3v2gA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 PHE A 145
ALA A 151
ILE A 161
LEU A 113
LEU A 198
 None
 1.09A 1yi4A-3v2gA:
undetectable		 1yi4A-3v2gA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 PHE A 145
ALA A 151
LEU A 113
ASP A 197
LEU A 198
 None
 1.02A 1yi4A-3v2gA:
undetectable		 1yi4A-3v2gA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 9 ALA A  88
GLY A  38
PRO A 144
VAL A 146
ILE A  96
 None
SO4  A 273 ( 4.9A)
None
None
None
 1.09A 2q5kA-3v2gA:
undetectable		 2q5kA-3v2gA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A  47
ALA A  46
GLY A  42
ILE A 243
GLY A  38
 None
None
None
None
SO4  A 273 ( 4.9A)
 0.89A 2qe6A-3v2gA:
6.1		 2qe6A-3v2gA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A  47
ALA A  46
GLY A  42
ILE A 243
GLY A  38
 None
None
None
None
SO4  A 273 ( 4.9A)
 0.96A 2qe6B-3v2gA:
2.4		 2qe6B-3v2gA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 TYR A 180
LEU A 168
TRP A 120
ASN A 167
 None
 1.03A 3k8mA-3v2gA:
2.9		 3k8mA-3v2gA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 TYR A 180
LEU A 168
TRP A 120
ASN A 167
 None
 1.01A 3k8mB-3v2gA:
undetectable		 3k8mB-3v2gA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 ALA A 117
GLY A 118
ALA A  65
ASN A  90
TYR A  62
 None
None
SO4  A 273 (-3.6A)
None
None
 1.21A 3qxyB-3v2gA:
undetectable
3qxyQ-3v2gA:
undetectable		 3qxyB-3v2gA:
24.30
3qxyQ-3v2gA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 108
ASP A 111
ILE A  76
ALA A  56
ALA A  52
 None
 0.97A 3sudC-3v2gA:
undetectable		 3sudC-3v2gA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 108
ASP A 111
ILE A  76
ALA A  56
ALA A  52
 None
 0.97A 3sueA-3v2gA:
undetectable		 3sueA-3v2gA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 108
ASP A 111
ILE A  76
ALA A  56
ALA A  52
 None
 1.01A 3sufD-3v2gA:
undetectable		 3sufD-3v2gA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 5 SER A 166
ILE A  43
TYR A 180
GLY A 211
 None
 1.05A 3uboB-3v2gA:
6.9		 3uboB-3v2gA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1480_0
(MJ0495-LIKE PROTEIN)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 LYS A  20
GLU A  54
ILE A  27
SER A  26
 None
 1.20A 4ac9C-3v2gA:
6.5		 4ac9C-3v2gA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 LYS A  20
GLU A  54
ILE A  27
SER A  26
 None
 1.22A 4acaC-3v2gA:
6.5		 4acaC-3v2gA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 LYS A  20
GLU A  54
ILE A  27
SER A  26
 None
 1.17A 4acbC-3v2gA:
2.8		 4acbC-3v2gA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 ASN A 270
ALA A 269
ARG A 231
 None
 0.73A 5cvtB-3v2gA:
4.3		 5cvtB-3v2gA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 ILE A  96
ILE A 100
THR A  61
ILE A  86
 None
 0.76A 5murB-3v2gA:
undetectable		 5murB-3v2gA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 164
LEU A 187
LEU A 246
ALA A 195
GLY A 193
 None
 0.96A 5uxdB-3v2gA:
undetectable		 5uxdB-3v2gA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3v2g 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 252
ALA A 251
VAL A 114
ILE A  47
ILE A 112
 None
 0.96A 6dh6A-3v2gA:
undetectable		 6dh6A-3v2gA:
14.67