SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 ALA A  25
TRP A 132
ARG A 134
LEU A  22
 None
 1.22A 1gahA-3v2hA:
undetectable		 1gahA-3v2hA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A  13
VAL A  47
SER A  10
LEU A  31
 None
 0.77A 2oa1B-3v2hA:
5.1		 2oa1B-3v2hA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 SER A 115
GLY A  15
VAL A 229
ILE A 138
ASN A 137
 None
 1.19A 3jb2A-3v2hA:
3.5		 3jb2A-3v2hA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 135
ILE A 124
ALA A 123
LEU A 113
LEU A 163
 None
 1.19A 3s79A-3v2hA:
undetectable		 3s79A-3v2hA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  22
MET A   0
ALA A 237
ILE A 136
ILE A  84
 None
 1.06A 3ut5B-3v2hA:
7.3		 3ut5B-3v2hA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 4 VAL A 186
VAL A 226
ASN A  88
ILE A 138
 None
 1.15A 4cutA-3v2hA:
0.3		 4cutA-3v2hA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 GLY A 175
SER A 174
ALA A 172
GLU A 173
 None
 0.95A 4m93B-3v2hA:
undetectable
4m93C-3v2hA:
undetectable		 4m93B-3v2hA:
20.89
4m93C-3v2hA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  22
MET A   0
ALA A 237
ILE A 136
ILE A  84
 None
 1.00A 4o2bB-3v2hA:
7.2		 4o2bB-3v2hA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 10 ALA A 237
ASP A 239
LEU A  22
ALA A  25
ALA A   5
 None
 1.18A 4zbrA-3v2hA:
undetectable		 4zbrA-3v2hA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  22
MET A   0
ALA A 237
ILE A 136
ILE A  84
 None
 0.99A 5itzB-3v2hA:
7.2		 5itzB-3v2hA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 135
ILE A 124
ALA A 123
LEU A 113
LEU A 163
 None
 1.19A 5jkvA-3v2hA:
undetectable		 5jkvA-3v2hA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 ILE A 181
ILE A 136
VAL A 249
ILE A 244
ALA A 241
 None
 1.10A 5lg3A-3v2hA:
undetectable		 5lg3A-3v2hA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 181
ILE A 136
VAL A 249
ILE A 244
ALA A 241
 None
 1.07A 5lg3E-3v2hA:
undetectable		 5lg3E-3v2hA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A  22
MET A   0
ALA A 237
ILE A 136
ILE A  84
 None
 0.97A 5mioB-3v2hA:
7.4		 5mioB-3v2hA:
20.84