SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 11 SER A  73
VAL A  27
LEU A  30
ALA A  31
ALA A  36
 None
 1.04A 1jinA-3v2iA:
undetectable		 1jinA-3v2iA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 ILE A  88
GLY A   7
ALA A  22
LEU A  95
TYR A 128
 None
 1.09A 1kiaC-3v2iA:
undetectable		 1kiaC-3v2iA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 ILE A  88
GLY A   7
ALA A  22
LEU A  95
TYR A 128
 None
 1.09A 1nbhB-3v2iA:
undetectable		 1nbhB-3v2iA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 10 ALA A  22
ALA A  91
VAL A 184
LEU A 104
GLN A  29
 None
 1.21A 1rlbE-3v2iA:
undetectable		 1rlbE-3v2iA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 10 ILE A   2
ILE A   5
VAL A  27
GLY A  23
VAL A  74
 None
 1.19A 3em0A-3v2iA:
undetectable		 3em0A-3v2iA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 LEU A  95
GLY A  23
LEU A   8
VAL A 158
ILE A 135
 None
 0.94A 3em6B-3v2iA:
undetectable		 3em6B-3v2iA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RNJ_A_EDTA1_0
(BRAIN-SPECIFIC
ANGIOGENESIS
INHIBITOR
1-ASSOCIATED PROTEIN
2)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 4 LYS A 103
ARG A 132
LEU A  97
ASP A  96
 None
 1.36A 3rnjA-3v2iA:
undetectable		 3rnjA-3v2iA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 7 ILE A 119
GLY A  71
SER A  73
SER A  70
LEU A  61
 None
 1.28A 3v7pA-3v2iA:
undetectable		 3v7pA-3v2iA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 ILE A   2
ILE A   5
VAL A  27
PHE A  24
LEU A 196
 None
 1.28A 3w67D-3v2iA:
undetectable		 3w67D-3v2iA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		8 / 9 HIS A  20
LEU A  95
GLY A 112
HIS A 113
ASN A 114
VAL A 154
VAL A 158
LEU A 159
 None
 0.53A 4qd3A-3v2iA:
33.4		 4qd3A-3v2iA:
47.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 7 THR A  16
GLY A  12
GLN A  64
ALA A  13
 None
 0.95A 4txnA-3v2iA:
8.0		 4txnA-3v2iA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 LEU A  95
PHE A 157
ARG A  19
ILE A 170
LEU A 131
 None
CIT  A 202 (-4.8A)
CIT  A 202 (-2.8A)
None
None
 1.22A 5ljcA-3v2iA:
undetectable		 5ljcA-3v2iA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 6 HIS A  20
ASP A  93
HIS A 113
MET A  67
 None
 1.48A 5m45A-3v2iA:
0.0		 5m45A-3v2iA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 6 HIS A  20
ASP A  93
HIS A 113
MET A  67
 None
 1.47A 5m45D-3v2iA:
0.0		 5m45D-3v2iA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 6 HIS A  20
ASP A  93
HIS A 113
MET A  67
 None
 1.48A 5m45G-3v2iA:
undetectable		 5m45G-3v2iA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 6 HIS A  20
ASP A  93
HIS A 113
MET A  67
 None
 1.47A 5m45J-3v2iA:
undetectable		 5m45J-3v2iA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		4 / 8 ALA A  22
ILE A 170
ALA A 173
ILE A 174
 None
 0.59A 5mvmA-3v2iA:
undetectable
5mvmB-3v2iA:
undetectable		 5mvmA-3v2iA:
16.36
5mvmB-3v2iA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 107
LYS A 105
ASN A  86
GLU A  87
LEU A  89
 None
 1.14A 5nwvA-3v2iA:
undetectable		 5nwvA-3v2iA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3v2i PEPTIDYL-TRNA
HYDROLASE
(Burkholderia
thailandensis) 		5 / 12 LEU A 131
VAL A 102
ALA A 172
ALA A 173
GLY A 100
 None
 1.12A 5tzoB-3v2iA:
undetectable		 5tzoB-3v2iA:
21.93