SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3v30 DNA-BINDING PROTEIN
RFXANK
(Homo
sapiens) 		4 / 8 PRO A 150
LEU A 176
GLY A 174
LEU A 144
 None
 0.94A 1ya4A-3v30A:
undetectable		 1ya4A-3v30A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 3v30 DNA-BINDING PROTEIN
RFXANK
(Homo
sapiens) 		5 / 12 VAL A 181
ARG A 212
PRO A 150
VAL A 140
LEU A 144
 None
 1.06A 3m6wA-3v30A:
undetectable		 3m6wA-3v30A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3v30 DNA-BINDING PROTEIN
RFXANK
(Homo
sapiens) 		4 / 8 SER A 159
ILE A 185
ILE A 183
LEU A 209
 None
 0.86A 4dtaB-3v30A:
undetectable		 4dtaB-3v30A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3v30 DNA-BINDING PROTEIN
RFXANK
(Homo
sapiens) 		5 / 12 SER A 162
SER A 159
ASP A 180
ASP A 182
ILE A 185
 None
 1.45A 4ktvA-3v30A:
undetectable
4ktvB-3v30A:
undetectable		 4ktvA-3v30A:
19.07
4ktvB-3v30A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3v30 DNA-BINDING PROTEIN
RFXANK
(Homo
sapiens) 		5 / 9 ALA A 208
ALA A 197
ALA A 164
SER A 165
GLY A 168
 None
 1.11A 6bklE-3v30A:
undetectable
6bklF-3v30A:
undetectable
6bklG-3v30A:
undetectable
6bklH-3v30A:
undetectable		 6bklE-3v30A:
9.88
6bklF-3v30A:
9.88
6bklG-3v30A:
9.88
6bklH-3v30A:
9.88