SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 3v3k PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Escherichia
coli) 		4 / 8 HIS B 118
SER B 119
VAL B 122
GLU B 162
 None
 0.83A 1jtvA-3v3kB:
undetectable		 1jtvA-3v3kB:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v3k CASPASE-9
PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Homo
sapiens;
Escherichia
coli) 		4 / 7 TRP A 340
TYR A 383
ARG B 155
TYR B 181
 None
 1.20A 1kiaC-3v3kA:
undetectable		 1kiaC-3v3kA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v3k CASPASE-9
PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Homo
sapiens;
Escherichia
coli) 		4 / 7 TRP A 340
TYR A 383
ARG B 155
TYR B 181
 None
 1.19A 1kiaD-3v3kA:
undetectable		 1kiaD-3v3kA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v3k CASPASE-9
PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Homo
sapiens;
Escherichia
coli) 		4 / 7 TRP A 340
TYR A 383
ARG B 155
TYR B 181
 None
 1.18A 1nbhB-3v3kA:
undetectable		 1nbhB-3v3kA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3v3k CASPASE-9
PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Homo
sapiens;
Escherichia
coli) 		4 / 7 TRP A 340
TYR A 383
ARG B 155
TYR B 181
 None
 1.19A 1nbhD-3v3kA:
undetectable		 1nbhD-3v3kA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3v3k CASPASE-9
(Homo
sapiens) 		5 / 12 ILE A 282
ILE A 234
ILE A 327
VAL A 212
PHE A 265
 None
 1.07A 2ygoA-3v3kA:
undetectable		 2ygoA-3v3kA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3v3k CASPASE-9
(Homo
sapiens) 		5 / 12 GLY A 163
LEU A 196
ASP A 228
VAL A 232
LEU A 279
 None
 0.98A 2yqzA-3v3kA:
undetectable		 2yqzA-3v3kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3v3k CASPASE-9
(Homo
sapiens) 		5 / 9 GLY A 225
ILE A 154
PHE A 400
GLY A 163
PHE A 198
 None
 1.30A 3ko0A-3v3kA:
undetectable
3ko0C-3v3kA:
undetectable		 3ko0A-3v3kA:
18.15
3ko0C-3v3kA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 3v3k CASPASE-9
(Homo
sapiens) 		5 / 10 GLY A 163
PHE A 198
GLY A 225
ILE A 154
PHE A 400
 None
 1.30A 3ko0L-3v3kA:
undetectable
3ko0N-3v3kA:
undetectable		 3ko0L-3v3kA:
18.15
3ko0N-3v3kA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3v3k CASPASE-9
(Homo
sapiens) 		5 / 10 GLY A 225
ILE A 154
PHE A 400
GLY A 163
PHE A 198
 None
 1.31A 3ko0R-3v3kA:
undetectable
3ko0T-3v3kA:
undetectable		 3ko0R-3v3kA:
18.15
3ko0T-3v3kA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3v3k PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Escherichia
coli) 		4 / 6 GLU B  27
PRO B 177
GLY B  96
ARG B  80
 None
 1.47A 5jcnB-3v3kB:
undetectable		 5jcnB-3v3kB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3v3k PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Escherichia
coli) 		5 / 11 GLN B  67
VAL B  73
SER B  74
ASP B  78
PRO B 144
 None
 1.42A 5jh7D-3v3kB:
undetectable		 5jh7D-3v3kB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 3v3k CASPASE-9
PUTATIVE
UNCHARACTERIZED
PROTEIN ECS1815
(Homo
sapiens;
Escherichia
coli) 		5 / 11 SER B 147
GLY A 245
GLY A 248
ASP A 247
MET A 211
 None
 1.14A 6i5zD-3v3kB:
undetectable		 6i5zD-3v3kB:
19.90