SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		4 / 8 ALA A  69
GLY A 101
THR A  35
ILE A  10
 None
 0.73A 1gtnI-3v3tA:
undetectable
1gtnJ-3v3tA:
undetectable		 1gtnI-3v3tA:
18.53
1gtnJ-3v3tA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 PHE A 184
ILE A  91
ILE A   5
ILE A 201
ILE A  89
 None
 1.37A 1r5lA-3v3tA:
2.8		 1r5lA-3v3tA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 10 ILE A  80
ALA A  78
ILE A  52
PRO A   9
ILE A  33
 None
 1.38A 2dm6A-3v3tA:
7.2
2dm6B-3v3tA:
7.3		 2dm6A-3v3tA:
23.56
2dm6B-3v3tA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 TYR A  28
PHE A 177
ILE A 213
ILE A 279
TYR A 160
 None
 1.48A 2efjA-3v3tA:
undetectable		 2efjA-3v3tA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A 103
GLY A  14
GLY A  11
GLY A  99
ILE A  17
 None
 0.92A 2oxtA-3v3tA:
3.2		 2oxtA-3v3tA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A 103
GLY A  14
GLY A  11
GLY A  99
VAL A  93
 None
 0.85A 2oxtA-3v3tA:
3.2		 2oxtA-3v3tA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A  15
ASN A  16
ASN A 174
ILE A  33
THR A 105
 None
 1.02A 3eeyA-3v3tA:
5.2		 3eeyA-3v3tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A  15
ASN A  16
ASN A 174
ILE A  33
THR A 105
 None
 1.01A 3eeyB-3v3tA:
2.3		 3eeyB-3v3tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A  15
ASN A  16
ASN A 174
ILE A  33
THR A 105
 None
 1.00A 3eeyH-3v3tA:
5.6		 3eeyH-3v3tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A  15
ASN A  16
ASN A 174
ILE A  33
THR A 105
 None
 1.02A 3eeyI-3v3tA:
5.4		 3eeyI-3v3tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		4 / 5 LYS A   2
ILE A 201
PHE A 184
ASP A 183
 None
 1.16A 3kp6A-3v3tA:
undetectable
3kp6B-3v3tA:
undetectable		 3kp6A-3v3tA:
20.22
3kp6B-3v3tA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		4 / 7 LEU A 204
SER A 210
ASN A 211
THR A 240
 None
 1.03A 3lm8B-3v3tA:
4.6
3lm8D-3v3tA:
4.2		 3lm8B-3v3tA:
20.69
3lm8D-3v3tA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 GLY A 101
GLY A  11
ALA A  97
ALA A 140
PHE A  92
 None
 1.09A 3p2kC-3v3tA:
4.0		 3p2kC-3v3tA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 LEU A  31
ILE A  33
ALA A  78
ALA A 112
GLY A 110
 None
 1.00A 4enhA-3v3tA:
undetectable		 4enhA-3v3tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		4 / 6 PHE A 123
ILE A  10
PRO A   9
PHE A  92
 None
 1.16A 4fgkA-3v3tA:
5.5		 4fgkA-3v3tA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 9 TYR A  50
ALA A  69
ARG A  62
ILE A 104
ILE A  52
 None
 1.49A 4oknB-3v3tA:
5.3		 4oknB-3v3tA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		4 / 5 MET A 207
GLU A 244
ARG A 268
ARG A 267
 None
 1.47A 4yshB-3v3tA:
undetectable		 4yshB-3v3tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED
(Clostridium
botulinum) 		5 / 12 ILE A   5
GLY A  26
ILE A 213
MET A 185
LEU A 162
 None
 0.97A 5e72A-3v3tA:
4.2		 5e72A-3v3tA:
21.04