SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3v42 FOLLICULIN
(Homo
sapiens) 		4 / 8 LEU A 349
PHE A 361
VAL A 368
LEU A 369
 None
 0.90A 3uniB-3v42A:
undetectable		 3uniB-3v42A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3v42 FOLLICULIN
(Homo
sapiens) 		4 / 5 LEU A 356
LEU A 364
LEU A 349
SER A 348
 None
 1.00A 3vhuA-3v42A:
undetectable		 3vhuA-3v42A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3v42 FOLLICULIN
(Homo
sapiens) 		4 / 8 GLY A 371
LEU A 391
ASN A 416
PHE A 417
 None
 1.23A 4m5mA-3v42A:
undetectable		 4m5mA-3v42A:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3v42 FOLLICULIN
(Homo
sapiens) 		4 / 5 ILE A 482
LEU A 549
GLU A 510
VAL A 517
 None
 1.00A 4nkxB-3v42A:
undetectable		 4nkxB-3v42A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3v42 FOLLICULIN
(Homo
sapiens) 		5 / 12 VAL A 439
VAL A 355
GLY A 357
SER A 360
LEU A 364
 None
 1.09A 5jvzA-3v42A:
undetectable		 5jvzA-3v42A:
16.82