SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v4b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1c9sA-3v4bA:
undetectable
1c9sK-3v4bA:
undetectable		 1c9sA-3v4bA:
12.60
1c9sK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1c9sA-3v4bA:
undetectable
1c9sB-3v4bA:
undetectable		 1c9sA-3v4bA:
12.60
1c9sB-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 1c9sD-3v4bA:
undetectable
1c9sE-3v4bA:
undetectable		 1c9sD-3v4bA:
12.60
1c9sE-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1c9sH-3v4bA:
undetectable
1c9sI-3v4bA:
undetectable		 1c9sH-3v4bA:
12.60
1c9sI-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1c9sJ-3v4bA:
undetectable
1c9sK-3v4bA:
undetectable		 1c9sJ-3v4bA:
12.60
1c9sK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1c9sL-3v4bA:
undetectable
1c9sM-3v4bA:
undetectable		 1c9sL-3v4bA:
12.60
1c9sM-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1c9sM-3v4bA:
undetectable
1c9sN-3v4bA:
undetectable		 1c9sM-3v4bA:
12.60
1c9sN-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1c9sO-3v4bA:
undetectable
1c9sP-3v4bA:
undetectable		 1c9sO-3v4bA:
12.60
1c9sP-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1c9sS-3v4bA:
undetectable
1c9sT-3v4bA:
undetectable		 1c9sS-3v4bA:
12.60
1c9sT-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1gtfA-3v4bA:
undetectable
1gtfK-3v4bA:
undetectable		 1gtfA-3v4bA:
12.60
1gtfK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 1gtfB-3v4bA:
undetectable
1gtfC-3v4bA:
undetectable		 1gtfB-3v4bA:
12.60
1gtfC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 1gtfE-3v4bA:
undetectable
1gtfF-3v4bA:
undetectable		 1gtfE-3v4bA:
12.60
1gtfF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1gtfF-3v4bA:
undetectable
1gtfG-3v4bA:
undetectable		 1gtfF-3v4bA:
12.60
1gtfG-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1gtfO-3v4bA:
undetectable
1gtfP-3v4bA:
undetectable		 1gtfO-3v4bA:
12.60
1gtfP-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1gtnR-3v4bA:
undetectable
1gtnS-3v4bA:
undetectable		 1gtnR-3v4bA:
12.60
1gtnS-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 TRP A 402
VAL A 391
PRO A 390
 None
 0.85A 1rg1A-3v4bA:
2.1		 1rg1A-3v4bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 TRP A 402
VAL A 391
PRO A 390
 None
 0.84A 1rh0A-3v4bA:
undetectable		 1rh0A-3v4bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1utdA-3v4bA:
undetectable
1utdB-3v4bA:
undetectable		 1utdA-3v4bA:
12.60
1utdB-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1utdC-3v4bA:
undetectable
1utdD-3v4bA:
undetectable		 1utdC-3v4bA:
12.60
1utdD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 1utdD-3v4bA:
undetectable
1utdE-3v4bA:
undetectable		 1utdD-3v4bA:
12.60
1utdE-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1utdG-3v4bA:
undetectable
1utdH-3v4bA:
undetectable		 1utdG-3v4bA:
12.60
1utdH-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 1utdA-3v4bA:
undetectable
1utdK-3v4bA:
undetectable		 1utdA-3v4bA:
12.60
1utdK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 11 GLY A  32
LEU A  47
ILE A 292
HIS A 288
ALA A 324
 None
 1.10A 2a58A-3v4bA:
undetectable
2a58E-3v4bA:
undetectable		 2a58A-3v4bA:
19.10
2a58E-3v4bA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ILE A 292
HIS A 288
ALA A 324
GLY A  32
LEU A  47
 None
 1.12A 2a58A-3v4bA:
undetectable
2a58B-3v4bA:
undetectable		 2a58A-3v4bA:
19.10
2a58B-3v4bA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ILE A 292
HIS A 288
ALA A 324
GLY A  32
LEU A  47
 None
 1.10A 2a58B-3v4bA:
undetectable
2a58C-3v4bA:
undetectable		 2a58B-3v4bA:
19.10
2a58C-3v4bA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 11 ILE A 292
HIS A 288
ALA A 324
GLY A  32
LEU A  47
 None
 1.11A 2a58C-3v4bA:
undetectable
2a58D-3v4bA:
undetectable		 2a58C-3v4bA:
19.10
2a58D-3v4bA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ILE A 292
HIS A 288
ALA A 324
GLY A  32
LEU A  47
 None
 1.12A 2a58D-3v4bA:
undetectable
2a58E-3v4bA:
undetectable		 2a58D-3v4bA:
19.10
2a58E-3v4bA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 HIS A 370
HIS A 327
ILE A  31
ALA A 354
TYR A  29
 None
 1.19A 2gl0A-3v4bA:
undetectable
2gl0B-3v4bA:
undetectable		 2gl0A-3v4bA:
16.67
2gl0B-3v4bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 11 HIS A 370
HIS A 327
ILE A  31
ALA A 354
TYR A  29
 None
 1.18A 2gl0B-3v4bA:
undetectable
2gl0C-3v4bA:
undetectable		 2gl0B-3v4bA:
16.67
2gl0C-3v4bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ILE A  31
ALA A 354
TYR A  29
HIS A 370
HIS A 327
 None
 1.17A 2gl0A-3v4bA:
undetectable
2gl0C-3v4bA:
undetectable		 2gl0A-3v4bA:
16.67
2gl0C-3v4bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 11 HIS A 370
HIS A 327
ILE A  31
ALA A 354
TYR A  29
 None
 1.17A 2gl0E-3v4bA:
undetectable
2gl0F-3v4bA:
undetectable		 2gl0E-3v4bA:
16.67
2gl0F-3v4bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 GLY A  32
HIS A 353
ASP A  33
ALA A  34
THR A  35
 None
 1.04A 2gluA-3v4bA:
undetectable		 2gluA-3v4bA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 7 MET A 322
ILE A 117
ARG A 114
GLY A 310
 None
 1.16A 2pnjB-3v4bA:
2.5		 2pnjB-3v4bA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 VAL A 391
TRP A 181
TRP A 400
 None
 1.22A 2xdcA-3v4bA:
undetectable
2xdcB-3v4bA:
undetectable		 2xdcA-3v4bA:
4.04
2xdcB-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 TRP A 400
VAL A 391
TRP A 181
 None
 1.21A 2xdcA-3v4bA:
undetectable
2xdcB-3v4bA:
undetectable		 2xdcA-3v4bA:
4.04
2xdcB-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 VAL A 391
TRP A 181
TRP A 400
 None
 1.37A 2xdcC-3v4bA:
undetectable
2xdcD-3v4bA:
undetectable		 2xdcC-3v4bA:
4.04
2xdcD-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 VAL A 391
TRP A 181
TRP A 400
 None
 1.23A 2y5mA-3v4bA:
undetectable
2y5mB-3v4bA:
undetectable		 2y5mA-3v4bA:
4.04
2y5mB-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 VAL A 391
TRP A 181
TRP A 400
 None
 1.22A 2y6nA-3v4bA:
undetectable
2y6nB-3v4bA:
undetectable		 2y6nA-3v4bA:
4.04
2y6nB-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 TRP A 400
VAL A 391
TRP A 181
 None
 1.20A 2y6nA-3v4bA:
undetectable
2y6nB-3v4bA:
undetectable		 2y6nA-3v4bA:
4.04
2y6nB-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 ALA A  34
LEU A  47
ALA A   6
ILE A  22
LEU A  93
 None
 1.17A 3fl9F-3v4bA:
undetectable		 3fl9F-3v4bA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 PRO A 333
PHE A 328
ALA A 299
 None
 0.68A 3itaD-3v4bA:
undetectable		 3itaD-3v4bA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ILE A 286
GLY A 291
GLY A 290
ALA A  92
VAL A  91
 None
 0.97A 3jb2A-3v4bA:
undetectable		 3jb2A-3v4bA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 GLY A  32
ALA A  92
ASP A  95
ILE A  96
ILE A   9
 None
 1.05A 3ogqB-3v4bA:
undetectable		 3ogqB-3v4bA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 4 GLY A  79
GLY A  82
THR A  84
LEU A  36
 CL  A 507 (-3.7A)
None
None
None
 0.89A 3si7C-3v4bA:
undetectable
3si7D-3v4bA:
undetectable		 3si7C-3v4bA:
23.34
3si7D-3v4bA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 ILE A  52
LEU A  20
ILE A  66
MET A  83
GLY A  82
 None
 1.30A 3sj4X-3v4bA:
undetectable		 3sj4X-3v4bA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 LEU A 232
HIS A 209
MET A 235
 None
 0.90A 3thrD-3v4bA:
undetectable		 3thrD-3v4bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ALA A 299
ASN A 334
ASP A  90
ILE A  63
ARG A 296
 None
 1.40A 3w37A-3v4bA:
2.4		 3w37A-3v4bA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 12 ALA A 299
ASN A 334
ASP A  90
ILE A  63
ARG A 296
 None
 1.40A 3welA-3v4bA:
5.8		 3welA-3v4bA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 VAL A 391
TRP A 181
TRP A 400
 None
 1.27A 3zq8A-3v4bA:
undetectable
3zq8B-3v4bA:
undetectable		 3zq8A-3v4bA:
4.04
3zq8B-3v4bA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 6 ILE A 298
GLN A 294
ILE A 292
ASP A  90
 None
 1.12A 4z4cA-3v4bA:
undetectable		 4z4cA-3v4bA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 6 ILE A 298
GLN A 294
ILE A 292
ASP A  90
 None
 1.22A 4z4dA-3v4bA:
undetectable		 4z4dA-3v4bA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5eeuA-3v4bA:
undetectable
5eeuB-3v4bA:
undetectable		 5eeuA-3v4bA:
12.60
5eeuB-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeuB-3v4bA:
undetectable
5eeuC-3v4bA:
undetectable		 5eeuB-3v4bA:
12.60
5eeuC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5eeuC-3v4bA:
undetectable
5eeuD-3v4bA:
undetectable		 5eeuC-3v4bA:
12.60
5eeuD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5eeuE-3v4bA:
undetectable
5eeuF-3v4bA:
undetectable		 5eeuE-3v4bA:
12.60
5eeuF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeuA-3v4bA:
undetectable
5eeuK-3v4bA:
undetectable		 5eeuA-3v4bA:
12.60
5eeuK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eeuN-3v4bA:
undetectable
5eeuO-3v4bA:
undetectable		 5eeuN-3v4bA:
12.60
5eeuO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eevB-3v4bA:
undetectable
5eevC-3v4bA:
undetectable		 5eevB-3v4bA:
12.60
5eevC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eevC-3v4bA:
undetectable
5eevD-3v4bA:
undetectable		 5eevC-3v4bA:
12.60
5eevD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5eevE-3v4bA:
undetectable
5eevF-3v4bA:
undetectable		 5eevE-3v4bA:
12.60
5eevF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eevH-3v4bA:
undetectable
5eevI-3v4bA:
undetectable		 5eevH-3v4bA:
12.60
5eevI-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eevA-3v4bA:
undetectable
5eevK-3v4bA:
undetectable		 5eevA-3v4bA:
12.60
5eevK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eevN-3v4bA:
undetectable
5eevO-3v4bA:
undetectable		 5eevN-3v4bA:
12.60
5eevO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eewB-3v4bA:
undetectable
5eewC-3v4bA:
undetectable		 5eewB-3v4bA:
12.60
5eewC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5eewC-3v4bA:
undetectable
5eewD-3v4bA:
undetectable		 5eewC-3v4bA:
12.60
5eewD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5eewE-3v4bA:
undetectable
5eewF-3v4bA:
undetectable		 5eewE-3v4bA:
12.60
5eewF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eewA-3v4bA:
undetectable
5eewK-3v4bA:
undetectable		 5eewA-3v4bA:
12.60
5eewK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eewN-3v4bA:
undetectable
5eewO-3v4bA:
undetectable		 5eewN-3v4bA:
12.60
5eewO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eexB-3v4bA:
undetectable
5eexC-3v4bA:
undetectable		 5eexB-3v4bA:
12.60
5eexC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eexC-3v4bA:
undetectable
5eexD-3v4bA:
undetectable		 5eexC-3v4bA:
12.60
5eexD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eexE-3v4bA:
undetectable
5eexF-3v4bA:
undetectable		 5eexE-3v4bA:
12.60
5eexF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eexN-3v4bA:
undetectable
5eexO-3v4bA:
undetectable		 5eexN-3v4bA:
12.60
5eexO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eexQ-3v4bA:
undetectable
5eexR-3v4bA:
undetectable		 5eexQ-3v4bA:
12.60
5eexR-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeyB-3v4bA:
undetectable
5eeyC-3v4bA:
undetectable		 5eeyB-3v4bA:
12.60
5eeyC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeyC-3v4bA:
undetectable
5eeyD-3v4bA:
undetectable		 5eeyC-3v4bA:
12.60
5eeyD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5eeyE-3v4bA:
undetectable
5eeyF-3v4bA:
undetectable		 5eeyE-3v4bA:
12.60
5eeyF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5eeyH-3v4bA:
undetectable
5eeyI-3v4bA:
undetectable		 5eeyH-3v4bA:
12.60
5eeyI-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeyA-3v4bA:
undetectable
5eeyK-3v4bA:
undetectable		 5eeyA-3v4bA:
12.60
5eeyK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eeyN-3v4bA:
undetectable
5eeyO-3v4bA:
undetectable		 5eeyN-3v4bA:
12.60
5eeyO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eeyQ-3v4bA:
undetectable
5eeyR-3v4bA:
undetectable		 5eeyQ-3v4bA:
12.60
5eeyR-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eezB-3v4bA:
undetectable
5eezC-3v4bA:
undetectable		 5eezB-3v4bA:
12.60
5eezC-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eezC-3v4bA:
undetectable
5eezD-3v4bA:
undetectable		 5eezC-3v4bA:
12.60
5eezD-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eezE-3v4bA:
undetectable
5eezF-3v4bA:
undetectable		 5eezE-3v4bA:
12.60
5eezF-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5eezH-3v4bA:
undetectable
5eezI-3v4bA:
undetectable		 5eezH-3v4bA:
12.60
5eezI-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eezA-3v4bA:
undetectable
5eezK-3v4bA:
undetectable		 5eezA-3v4bA:
12.60
5eezK-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5eezN-3v4bA:
undetectable
5eezO-3v4bA:
undetectable		 5eezN-3v4bA:
12.60
5eezO-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5eezQ-3v4bA:
undetectable
5eezR-3v4bA:
undetectable		 5eezQ-3v4bA:
12.60
5eezR-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef0B-3v4bA:
undetectable
5ef0C-3v4bA:
undetectable		 5ef0B-3v4bA:
12.60
5ef0C-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef0C-3v4bA:
undetectable
5ef0D-3v4bA:
undetectable		 5ef0C-3v4bA:
12.60
5ef0D-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5ef0E-3v4bA:
undetectable
5ef0F-3v4bA:
undetectable		 5ef0E-3v4bA:
12.60
5ef0F-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef0H-3v4bA:
undetectable
5ef0I-3v4bA:
undetectable		 5ef0H-3v4bA:
12.60
5ef0I-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef0N-3v4bA:
undetectable
5ef0O-3v4bA:
undetectable		 5ef0N-3v4bA:
12.60
5ef0O-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef0Q-3v4bA:
undetectable
5ef0R-3v4bA:
undetectable		 5ef0Q-3v4bA:
12.60
5ef0R-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef1B-3v4bA:
undetectable
5ef1C-3v4bA:
undetectable		 5ef1B-3v4bA:
12.60
5ef1C-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef1C-3v4bA:
undetectable
5ef1D-3v4bA:
undetectable		 5ef1C-3v4bA:
12.60
5ef1D-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5ef1E-3v4bA:
undetectable
5ef1F-3v4bA:
undetectable		 5ef1E-3v4bA:
12.60
5ef1F-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef1H-3v4bA:
undetectable
5ef1I-3v4bA:
undetectable		 5ef1H-3v4bA:
12.60
5ef1I-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef1A-3v4bA:
undetectable
5ef1K-3v4bA:
undetectable		 5ef1A-3v4bA:
12.60
5ef1K-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef1N-3v4bA:
undetectable
5ef1O-3v4bA:
undetectable		 5ef1N-3v4bA:
12.60
5ef1O-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef1Q-3v4bA:
undetectable
5ef1R-3v4bA:
undetectable		 5ef1Q-3v4bA:
12.60
5ef1R-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef2B-3v4bA:
undetectable
5ef2C-3v4bA:
undetectable		 5ef2B-3v4bA:
12.60
5ef2C-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef2C-3v4bA:
undetectable
5ef2D-3v4bA:
undetectable		 5ef2C-3v4bA:
12.60
5ef2D-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5ef2E-3v4bA:
undetectable
5ef2F-3v4bA:
undetectable		 5ef2E-3v4bA:
12.60
5ef2F-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.49A 5ef2H-3v4bA:
undetectable
5ef2I-3v4bA:
undetectable		 5ef2H-3v4bA:
12.60
5ef2I-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef2A-3v4bA:
undetectable
5ef2K-3v4bA:
undetectable		 5ef2A-3v4bA:
12.60
5ef2K-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef2N-3v4bA:
undetectable
5ef2O-3v4bA:
undetectable		 5ef2N-3v4bA:
12.60
5ef2O-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef2Q-3v4bA:
undetectable
5ef2R-3v4bA:
undetectable		 5ef2Q-3v4bA:
12.60
5ef2R-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef3B-3v4bA:
undetectable
5ef3C-3v4bA:
undetectable		 5ef3B-3v4bA:
12.60
5ef3C-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef3C-3v4bA:
undetectable
5ef3D-3v4bA:
undetectable		 5ef3C-3v4bA:
12.60
5ef3D-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.47A 5ef3E-3v4bA:
undetectable
5ef3F-3v4bA:
undetectable		 5ef3E-3v4bA:
12.60
5ef3F-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef3H-3v4bA:
undetectable
5ef3I-3v4bA:
undetectable		 5ef3H-3v4bA:
12.60
5ef3I-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.50A 5ef3N-3v4bA:
undetectable
5ef3O-3v4bA:
undetectable		 5ef3N-3v4bA:
12.60
5ef3O-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 GLY A 261
THR A 285
HIS A 288
THR A 284
ILE A 282
 None
 1.48A 5ef3Q-3v4bA:
undetectable
5ef3R-3v4bA:
undetectable		 5ef3Q-3v4bA:
12.60
5ef3R-3v4bA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 6 VAL A 372
HIS A 370
CYH A 321
HIS A 327
 None
 1.46A 5hrqH-3v4bA:
undetectable
5hrqK-3v4bA:
undetectable
5hrqL-3v4bA:
undetectable		 5hrqH-3v4bA:
6.54
5hrqK-3v4bA:
6.97
5hrqL-3v4bA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_B_Z80B401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 ILE A 274
PHE A 301
THR A 284
ASP A 269
ILE A 298
 None
 1.31A 5lg3B-3v4bA:
0.9		 5lg3B-3v4bA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_D_Z80D401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 9 ILE A 274
PHE A 301
THR A 284
ASP A 269
ILE A 298
 None
 1.26A 5lg3D-3v4bA:
0.9		 5lg3D-3v4bA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 ILE A 274
PHE A 301
THR A 284
ASP A 269
ILE A 298
 None
 1.28A 5lg3F-3v4bA:
undetectable		 5lg3F-3v4bA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 ILE A 274
PHE A 301
THR A 284
ASP A 269
ILE A 298
 None
 1.29A 5lg3G-3v4bA:
undetectable		 5lg3G-3v4bA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		5 / 10 GLN A 338
LEU A 105
GLY A 371
GLY A 365
ALA A 324
 None
 1.16A 5o96E-3v4bA:
undetectable
5o96F-3v4bA:
undetectable		 5o96E-3v4bA:
19.33
5o96F-3v4bA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		4 / 6 TRP A 402
LEU A 317
ASP A 237
GLU A 262
 None
None
MG  A 403 ( 4.6A)
MG  A 403 ( 2.5A)
 1.46A 6djzC-3v4bA:
undetectable		 6djzC-3v4bA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3v4b STARVATION SENSING
PROTEIN RSPA
(Cellvibrio
japonicus) 		3 / 3 ASP A 174
LEU A 175
ARG A  39
 None
 0.69A 7dfrA-3v4bA:
undetectable		 7dfrA-3v4bA:
15.79