SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v4d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDU_D_ESTD352_1 (17-BETA-HYDROXYSTERO ID DEHYDROGENASE)	3v4d	AMINOACRYLATE PERACID REDUCTASE RUTC (Escherichia coli)	4 / 6	SER A 31 VAL A 30 GLY A 21 GLU A 64	None	0.95A	1fduD-3v4dA: undetectable	1fduD-3v4dA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DEU_A_SALA305_1 (TRANSCRIPTIONAL REGULATOR SLYA)	3v4d	AMINOACRYLATE PERACID REDUCTASE RUTC (Escherichia coli)	4 / 7	THR A 52 VAL A 55 ILE A 120 ILE A 78	None	0.84A	3deuA-3v4dA: undetectable	3deuA-3v4dA: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SOA_A_DB8A445_1 (CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER)	3v4d	AMINOACRYLATE PERACID REDUCTASE RUTC (Escherichia coli)	4 / 6	LEU A 111 VAL A 112 PHE A 36 PHE A 18	None	1.14A	3soaA-3v4dA: undetectable	3soaA-3v4dA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_A_BEZA1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	3v4d	AMINOACRYLATE PERACID REDUCTASE RUTC (Escherichia coli)	4 / 6	GLY A 21 THR A 22 SER A 31 VAL A 19	None	1.12A	5ewuA-3v4dA: undetectable	5ewuA-3v4dA: 18.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FDU_D_ESTD352_1","17-BETA-HYDROXYSTEROID DEHYDROGENASE","3v4d","AMINOACRYLATE PERACID REDUCTASE RUTC","Escherichia coli",4,"SER A  31;VAL A  30;GLY A  21;GLU A  64","None","0.95A","1fduD-3v4dA:undetectable","1fduD-3v4dA:19.51"],["3DEU_A_SALA305_1","TRANSCRIPTIONAL REGULATOR SLYA","3v4d","AMINOACRYLATE PERACID REDUCTASE RUTC","Escherichia coli",4,"THR A  52;VAL A  55;ILE A 120;ILE A  78","None","0.84A","3deuA-3v4dA:undetectable","3deuA-3v4dA:22.54"],["3SOA_A_DB8A445_1","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER","3v4d","AMINOACRYLATE PERACID REDUCTASE RUTC","Escherichia coli",4,"LEU A 111;VAL A 112;PHE A  36;PHE A  18","None","1.14A","3soaA-3v4dA:undetectable","3soaA-3v4dA:14.85"],["5EWU_A_BEZA1401_0","MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC","3v4d","AMINOACRYLATE PERACID REDUCTASE RUTC","Escherichia coli",4,"GLY A  21;THR A  22;SER A  31;VAL A  19","None","1.12A","5ewuA-3v4dA:undetectable","5ewuA-3v4dA:18.03"]]