SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v4p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 11 LEU A 427
VAL A 426
ILE A 385
ILE A 367
VAL A   3
 None
 1.21A 1gx9A-3v4pA:
undetectable		 1gx9A-3v4pA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 7 PHE A 585
ARG A 499
ILE A 583
ILE A 463
 None
 0.85A 1oniD-3v4pA:
undetectable
1oniF-3v4pA:
undetectable		 1oniD-3v4pA:
13.03
1oniF-3v4pA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 SER A 424
LEU A 394
LEU A 342
VAL A 417
PHE A 397
 None
 1.49A 1uobA-3v4pA:
undetectable		 1uobA-3v4pA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		3 / 3 THR A  40
PRO A  52
PRO A  39
 15P  A 612 (-3.4A)
None
None
 0.86A 2d55C-3v4pA:
undetectable		 2d55C-3v4pA:
1.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 10 GLU A 562
ASP A 408
LEU A 427
LEU A   9
TYR A  11
 None
CA  A 603 (-3.3A)
None
None
None
 1.49A 2ha6A-3v4pA:
undetectable		 2ha6A-3v4pA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 LYS A 126
ILE A 121
GLU A  88
ILE A 118
 None
 0.96A 2j9dJ-3v4pA:
undetectable
2j9dK-3v4pA:
undetectable
2j9dL-3v4pA:
undetectable		 2j9dJ-3v4pA:
12.18
2j9dK-3v4pA:
12.18
2j9dL-3v4pA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 ILE A 369
ILE A 367
LEU A 342
ASN A 341
VAL A 417
 None
 0.92A 2nnhA-3v4pA:
undetectable		 2nnhA-3v4pA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 290
ILE A 339
SER A 276
GLY A 274
 None
 0.67A 2otfA-3v4pA:
undetectable		 2otfA-3v4pA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 VAL A 353
TYR A 370
VAL A 306
SER A 276
 None
 1.21A 2x45C-3v4pA:
undetectable		 2x45C-3v4pA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 THR A 141
TRP A  33
HIS A  28
LEU A  94
 None
None
NAG  A 605 ( 4.4A)
None
 1.11A 3ablA-3v4pA:
undetectable
3ablC-3v4pA:
undetectable
3ablP-3v4pA:
undetectable		 3ablA-3v4pA:
22.31
3ablC-3v4pA:
17.92
3ablP-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 LEU A  94
THR A 141
TRP A  33
HIS A  28
 None
None
None
NAG  A 605 ( 4.4A)
 1.08A 3ablC-3v4pA:
undetectable
3ablN-3v4pA:
undetectable
3ablP-3v4pA:
undetectable		 3ablC-3v4pA:
17.92
3ablN-3v4pA:
22.31
3ablP-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 GLY A 274
GLY A 238
ILE A 355
LEU A 291
GLY A 293
 None
 0.86A 3axzA-3v4pA:
undetectable		 3axzA-3v4pA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 342
ILE A 367
ILE A 345
GLY A 403
 None
 0.95A 3bufA-3v4pA:
undetectable		 3bufA-3v4pA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 PRO A 358
SER A 400
LEU A 363
SER A 395
 None
 1.21A 3ijxH-3v4pA:
undetectable		 3ijxH-3v4pA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 PRO A 358
SER A 400
LEU A 363
SER A 395
 None
 1.17A 3iluH-3v4pA:
undetectable		 3iluH-3v4pA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		3 / 3 PRO A 149
PHE A 162
ALA A 204
 None
 0.61A 3itaD-3v4pA:
undetectable		 3itaD-3v4pA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		3 / 3 ASP A 414
ARG A 429
ALA A 407
 CA  A 603 (-2.8A)
None
None
 0.63A 3mbgC-3v4pA:
undetectable		 3mbgC-3v4pA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 ASP A 344
ASP A 346
ASP A 352
ARG A 373
 CA  A 602 (-3.9A)
CA  A 602 (-3.5A)
CA  A 602 (-2.7A)
None
 1.45A 3naiA-3v4pA:
undetectable		 3naiA-3v4pA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 LEU A  25
GLU A 351
GLY A 403
SER A 402
ASP A 414
 None
None
None
None
CA  A 603 (-2.8A)
 1.22A 3ou6C-3v4pA:
undetectable		 3ou6C-3v4pA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 LEU A  25
GLU A 351
GLY A 403
SER A 402
ASP A 414
 None
None
None
None
CA  A 603 (-2.8A)
 1.30A 3ou6D-3v4pA:
undetectable		 3ou6D-3v4pA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 THR A  67
GLY A  65
PRO A  64
ASN A  63
 None
 1.10A 3u8qA-3v4pA:
undetectable		 3u8qA-3v4pA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 LEU A  94
THR A 141
TRP A  33
HIS A  28
 None
None
None
NAG  A 605 ( 4.4A)
 1.08A 3x2qC-3v4pA:
undetectable
3x2qN-3v4pA:
undetectable
3x2qP-3v4pA:
undetectable		 3x2qC-3v4pA:
17.92
3x2qN-3v4pA:
22.31
3x2qP-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 VAL A 222
GLY A 223
VAL A 235
SER A 191
PRO A 183
 None
 1.26A 4bvaB-3v4pA:
undetectable		 4bvaB-3v4pA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 GLN A 230
GLY A 225
ASN A 341
GLU A 234
 None
 1.01A 4fgjA-3v4pA:
undetectable
4fgjB-3v4pA:
undetectable		 4fgjA-3v4pA:
17.03
4fgjB-3v4pA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 9 GLU A 243
GLY A 246
PRO A 240
GLY A 219
TYR A 220
 None
 1.37A 4fimA-3v4pA:
undetectable		 4fimA-3v4pA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 ALA A 419
GLY A 387
ILE A 369
ALA A 354
GLY A 356
 None
 1.05A 4r29D-3v4pA:
undetectable		 4r29D-3v4pA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 GLY A 274
GLY A 238
ILE A 355
LEU A 291
GLY A 293
 None
 0.83A 4yvgA-3v4pA:
undetectable		 4yvgA-3v4pA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		3 / 5 GLY A 304
GLY A 336
GLU A 337
 None
 0.52A 4z2eA-3v4pA:
undetectable
4z2eD-3v4pA:
undetectable		 4z2eA-3v4pA:
21.63
4z2eD-3v4pA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 11 GLN A 230
GLY A 225
ASN A 341
GLU A 234
ILE A 250
 None
 1.37A 4zvmA-3v4pA:
undetectable
4zvmB-3v4pA:
undetectable		 4zvmA-3v4pA:
17.23
4zvmB-3v4pA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 SER A 276
GLY A 293
ALA A 332
GLY A 304
 None
 0.59A 5albL-3v4pA:
4.1		 5albL-3v4pA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 7 GLY A 181
SER A 191
GLY A 190
ALA A 167
 None
 0.81A 5e26A-3v4pA:
undetectable
5e26B-3v4pA:
undetectable		 5e26A-3v4pA:
20.33
5e26B-3v4pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 7 ALA A 167
GLY A 181
SER A 191
GLY A 190
 None
 0.78A 5e26A-3v4pA:
undetectable
5e26B-3v4pA:
undetectable		 5e26A-3v4pA:
20.33
5e26B-3v4pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 7 GLY A 181
SER A 191
GLY A 190
ALA A 167
 None
 0.82A 5e26C-3v4pA:
undetectable
5e26D-3v4pA:
undetectable		 5e26C-3v4pA:
20.33
5e26D-3v4pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 ALA A 167
GLY A 181
SER A 191
GLY A 190
 None
 0.81A 5e26C-3v4pA:
undetectable
5e26D-3v4pA:
undetectable		 5e26C-3v4pA:
20.33
5e26D-3v4pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 ASP A 375
ALA A 374
ASP A 344
GLN A 404
PHE A 350
 None
None
CA  A 602 (-3.9A)
None
None
 1.25A 5hfjF-3v4pA:
undetectable		 5hfjF-3v4pA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 ASP A 375
ALA A 374
ASP A 344
GLN A 404
PHE A 350
 None
None
CA  A 602 (-3.9A)
None
None
 1.29A 5hfjH-3v4pA:
undetectable		 5hfjH-3v4pA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 LEU A  94
THR A 141
TRP A  33
HIS A  28
 None
None
None
NAG  A 605 ( 4.4A)
 1.12A 5iy5C-3v4pA:
undetectable
5iy5N-3v4pA:
undetectable
5iy5P-3v4pA:
undetectable		 5iy5C-3v4pA:
18.20
5iy5N-3v4pA:
22.31
5iy5P-3v4pA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 THR A 141
TRP A  33
HIS A  28
LEU A  94
 None
None
NAG  A 605 ( 4.4A)
None
 1.07A 5w97A-3v4pA:
undetectable
5w97C-3v4pA:
undetectable
5w97c-3v4pA:
undetectable		 5w97A-3v4pA:
22.31
5w97C-3v4pA:
17.92
5w97c-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 7 LEU A  94
THR A 141
TRP A  33
HIS A  28
 None
None
None
NAG  A 605 ( 4.4A)
 1.02A 5w97C-3v4pA:
undetectable
5w97a-3v4pA:
undetectable
5w97c-3v4pA:
undetectable		 5w97C-3v4pA:
17.92
5w97a-3v4pA:
22.31
5w97c-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 THR A 141
TRP A  33
HIS A  28
LEU A  94
 None
None
NAG  A 605 ( 4.4A)
None
 1.12A 5x19A-3v4pA:
undetectable
5x19C-3v4pA:
undetectable
5x19P-3v4pA:
undetectable		 5x19A-3v4pA:
22.31
5x19C-3v4pA:
17.92
5x19P-3v4pA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 10 LEU A  10
SER A 424
ILE A 390
SER A 395
GLY A 387
 None
 1.44A 6dlzA-3v4pA:
undetectable
6dlzD-3v4pA:
undetectable		 6dlzA-3v4pA:
9.06
6dlzD-3v4pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 10 ILE A 390
SER A 395
GLY A 387
LEU A  10
SER A 424
 None
 1.44A 6dlzB-3v4pA:
undetectable
6dlzC-3v4pA:
undetectable		 6dlzB-3v4pA:
9.06
6dlzC-3v4pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 10 LEU A  10
SER A 424
ILE A 390
SER A 395
GLY A 387
 None
 1.44A 6dm1A-3v4pA:
undetectable
6dm1D-3v4pA:
undetectable		 6dm1A-3v4pA:
9.06
6dm1D-3v4pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 10 ILE A 390
SER A 395
GLY A 387
LEU A  10
SER A 424
 None
 1.44A 6dm1B-3v4pA:
undetectable
6dm1C-3v4pA:
undetectable		 6dm1B-3v4pA:
9.06
6dm1C-3v4pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 177
THR A 199
PRO A 149
ARG A 146
 None
NAG  A 606 ( 4.4A)
None
None
 1.36A 6ew0B-3v4pA:
undetectable		 6ew0B-3v4pA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 177
THR A 199
PRO A 149
ARG A 146
 None
NAG  A 606 ( 4.4A)
None
None
 1.36A 6ew0D-3v4pA:
undetectable		 6ew0D-3v4pA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 177
THR A 199
PRO A 149
ARG A 146
 None
NAG  A 606 ( 4.4A)
None
None
 1.36A 6ew0H-3v4pA:
undetectable		 6ew0H-3v4pA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 5 LEU A 177
THR A 199
PRO A 149
ARG A 146
 None
NAG  A 606 ( 4.4A)
None
None
 1.36A 6ew0I-3v4pA:
undetectable		 6ew0I-3v4pA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 6 LEU A 427
TYR A  11
VAL A 135
GLY A  61
 None
 0.94A 6hd4B-3v4pA:
undetectable		 6hd4B-3v4pA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		5 / 12 LEU A 325
ILE A 367
GLY A 356
GLY A 336
VAL A 417
 None
 0.80A 6iftA-3v4pA:
undetectable		 6iftA-3v4pA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v4p INTEGRIN ALPHA-4
(Homo
sapiens) 		4 / 8 LEU A  94
THR A 141
TRP A  33
HIS A  28
 None
None
None
NAG  A 605 ( 4.4A)
 1.06A 6nknC-3v4pA:
undetectable
6nknN-3v4pA:
undetectable
6nknP-3v4pA:
undetectable		 6nknC-3v4pA:
17.92
6nknN-3v4pA:
22.31
6nknP-3v4pA:
17.92