SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ARG C 479
LEU C 481
VAL C 505
GLY C 542
 None
 0.93A 1hrkA-3v64C:
undetectable		 1hrkA-3v64C:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ARG C 479
LEU C 481
VAL C 505
GLY C 542
 None
 0.93A 1hrkB-3v64C:
undetectable		 1hrkB-3v64C:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 7 ASN C 667
PHE C 669
SER C 432
ARG C 427
 None
 1.13A 1rqpB-3v64C:
undetectable		 1rqpB-3v64C:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ASN C 667
PHE C 669
SER C 432
ARG C 427
 None
 1.09A 1rqpC-3v64C:
undetectable		 1rqpC-3v64C:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ASN C 667
PHE C 669
SER C 432
ARG C 427
 None
 1.13A 1rqpA-3v64C:
undetectable		 1rqpA-3v64C:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 ARG C 694
ILE C 471
GLY C 514
GLY C 515
ILE C 559
 None
 0.80A 2o4kA-3v64C:
undetectable		 2o4kA-3v64C:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ARG C 479
LEU C 481
VAL C 505
GLY C 542
 None
 0.89A 2po5A-3v64C:
undetectable		 2po5A-3v64C:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ARG C 479
LEU C 481
VAL C 505
GLY C 542
 None
 0.84A 2po5B-3v64C:
undetectable		 2po5B-3v64C:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ASN C 667
PHE C 669
SER C 432
ARG C 427
 None
 1.17A 2v7uA-3v64C:
undetectable		 2v7uA-3v64C:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 7 ASN C 667
PHE C 669
SER C 432
ARG C 427
 None
 1.17A 2v7uB-3v64C:
undetectable		 2v7uB-3v64C:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 VAL C 648
THR C 647
ASP C 686
ALA C 558
THR C 571
 None
 1.17A 3a35B-3v64C:
undetectable		 3a35B-3v64C:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 6 GLN C 693
GLY C 423
HIS C 691
HIS C 477
 None
 1.37A 3ai8B-3v64C:
undetectable		 3ai8B-3v64C:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 LEU C 597
GLU C 580
ILE C 592
 None
 0.55A 3czhA-3v64C:
undetectable		 3czhA-3v64C:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA302_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 5 PRO C 696
MET C 564
HIS C 562
LEU C 627
 None
 1.42A 4ww7A-3v64C:
0.9		 4ww7A-3v64C:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 LEU C 525
LEU C 516
ARG C 494
LEU C 493
ILE C 492
 None
 1.05A 4x1gA-3v64C:
undetectable		 4x1gA-3v64C:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG C 589
VAL C 547
TRP C 550
 None
 1.04A 5fvoA-3v64C:
undetectable		 5fvoA-3v64C:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_1
(OXAC)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 5 TYR C 424
HIS C 562
ASP C 606
ASP C 651
 None
 1.43A 5w7pA-3v64C:
undetectable		 5w7pA-3v64C:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 ALA C 625
LEU C 627
THR C 604
LEU C 603
ALA C 560
 None
 0.78A 6djzC-3v64C:
undetectable		 6djzC-3v64C:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 ILE C 676
GLN C 674
VAL C 635
SER C 652
 None
 0.98A 6fbvC-3v64C:
undetectable		 6fbvC-3v64C:
15.62