SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 8 PHE B 644
ASP B 686
GLY B 515
GLY B 514
 None
 0.83A 1ekjE-3v65B:
undetectable
1ekjF-3v65B:
undetectable		 1ekjE-3v65B:
19.85
1ekjF-3v65B:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3v65 AGRIN
(Rattus
norvegicus) 		4 / 8 LEU A1833
SER A1793
ASN A1794
GLN A1887
 None
 1.14A 1ig3A-3v65A:
undetectable
1ig3B-3v65A:
undetectable		 1ig3A-3v65A:
21.27
1ig3B-3v65A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 TRP B 520
HIS B 562
MET B 564
 None
 1.44A 1l5qB-3v65B:
undetectable		 1l5qB-3v65B:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG B 589
VAL B 547
TRP B 550
 None
 0.95A 1qw6A-3v65B:
undetectable		 1qw6A-3v65B:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG B 589
VAL B 547
TRP B 550
 None
 0.89A 1qwcA-3v65B:
undetectable		 1qwcA-3v65B:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG B 589
VAL B 547
TRP B 550
 None
 0.90A 1vagA-3v65B:
undetectable		 1vagA-3v65B:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG B 589
VAL B 547
TRP B 550
 None
 0.96A 1zviA-3v65B:
undetectable		 1zviA-3v65B:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3v65 AGRIN
(Rattus
norvegicus) 		5 / 11 ALA A1860
LEU A1920
LEU A1800
LEU A1824
LEU A1798
 None
 0.85A 2ceoA-3v65A:
undetectable		 2ceoA-3v65A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3v65 AGRIN
LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 7 GLU A1780
LYS B 618
ASN A1783
ALA B 617
 None
 1.45A 2ejgB-3v65A:
undetectable		 2ejgB-3v65A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3v65 AGRIN
(Rattus
norvegicus) 		5 / 10 ALA A1860
LEU A1920
LEU A1800
LEU A1824
LEU A1798
 None
 0.93A 2riwA-3v65A:
undetectable
2riwB-3v65A:
undetectable		 2riwA-3v65A:
19.30
2riwB-3v65A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 TRP B 573
VAL B 615
TRP B 599
 None
 1.33A 2xdcC-3v65B:
undetectable
2xdcD-3v65B:
undetectable		 2xdcC-3v65B:
5.66
2xdcD-3v65B:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 3v65 AGRIN
(Rattus
norvegicus) 		5 / 10 ALA A1860
LEU A1920
LEU A1800
LEU A1824
LEU A1798
 None
 0.88A 2xn6A-3v65A:
undetectable
2xn6B-3v65A:
undetectable		 2xn6A-3v65A:
21.61
2xn6B-3v65A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 3v65 AGRIN
(Rattus
norvegicus) 		5 / 10 ALA A1860
LEU A1920
LEU A1800
LEU A1824
LEU A1798
 None
 0.90A 2xn7A-3v65A:
undetectable
2xn7B-3v65A:
undetectable		 2xn7A-3v65A:
21.61
2xn7B-3v65A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 VAL B 648
THR B 647
ALA B 558
THR B 571
ILE B 579
 None
 1.12A 3a35B-3v65B:
undetectable		 3a35B-3v65B:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 VAL B 648
THR B 647
ASP B 686
ALA B 558
THR B 571
 None
 1.18A 3a35B-3v65B:
undetectable		 3a35B-3v65B:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 VAL B 648
THR B 647
ALA B 558
THR B 571
ILE B 579
 None
 1.16A 3a3bA-3v65B:
undetectable		 3a3bA-3v65B:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 4 SER B 716
GLY B 717
GLY B 586
GLY B 588
 None
 0.70A 3bogB-3v65B:
undetectable
3bogD-3v65B:
undetectable		 3bogB-3v65B:
undetectable
3bogD-3v65B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 LEU B 597
GLU B 580
ILE B 592
 None
 0.48A 3czhA-3v65B:
undetectable		 3czhA-3v65B:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 11 ARG B 694
ILE B 471
GLY B 515
ILE B 559
THR B 647
 None
 1.11A 3spkA-3v65B:
undetectable		 3spkA-3v65B:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 ARG B 694
ILE B 471
GLY B 515
ILE B 559
THR B 647
 None
 1.06A 3spkB-3v65B:
undetectable		 3spkB-3v65B:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3v65 AGRIN
(Rattus
norvegicus) 		4 / 5 LEU A1810
LEU A1824
LEU A1800
SER A1799
 None
 1.01A 3vhuA-3v65A:
undetectable		 3vhuA-3v65A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 10 ALA B 558
GLY B 515
LEU B 561
ASP B 686
LEU B 516
 None
 1.20A 3wdmB-3v65B:
undetectable		 3wdmB-3v65B:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 TRP B 573
VAL B 615
TRP B 599
 None
 1.21A 3zq8A-3v65B:
undetectable
3zq8B-3v65B:
undetectable		 3zq8A-3v65B:
5.66
3zq8B-3v65B:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		4 / 5 ILE B 605
ILE B 579
TYR B 569
GLU B 580
 None
 1.18A 4a99D-3v65B:
undetectable		 4a99D-3v65B:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3v65 AGRIN
(Rattus
norvegicus) 		5 / 12 MET A1822
ALA A1825
THR A1802
LEU A1831
GLY A1807
 None
 0.97A 4ls7A-3v65A:
undetectable
4ls7B-3v65A:
undetectable		 4ls7A-3v65A:
19.14
4ls7B-3v65A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 PRO B 455
LEU B 442
GLY B 609
ASP B 606
THR B 689
 None
 1.35A 4mubA-3v65B:
undetectable		 4mubA-3v65B:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 LEU B 525
LEU B 516
ARG B 494
LEU B 493
ILE B 492
 None
 1.03A 4x1fA-3v65B:
undetectable		 4x1fA-3v65B:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 LEU B 525
LEU B 516
ARG B 494
LEU B 493
ILE B 492
 None
 1.01A 4x1gA-3v65B:
undetectable		 4x1gA-3v65B:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3v65 AGRIN
(Rattus
norvegicus) 		4 / 7 ARG A1859
ASP A1922
ARG A1921
THR A1947
 None
 0.89A 5btgA-3v65A:
undetectable
5btgC-3v65A:
undetectable
5btgD-3v65A:
undetectable		 5btgA-3v65A:
18.07
5btgC-3v65A:
18.07
5btgD-3v65A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		3 / 3 ARG B 589
VAL B 547
TRP B 550
 None
 0.92A 5fvoA-3v65B:
undetectable		 5fvoA-3v65B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3v65 AGRIN
(Rattus
norvegicus) 		4 / 4 LEU A1844
GLY A1879
SER A1880
SER A1881
 None
 1.29A 5uunA-3v65A:
undetectable		 5uunA-3v65A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3v65 AGRIN
(Rattus
norvegicus) 		4 / 4 LEU A1844
GLY A1879
SER A1880
SER A1881
 None
 1.24A 5uunB-3v65A:
undetectable		 5uunB-3v65A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 LEU B 443
LEU B 497
ALA B 495
LEU B 463
LEU B 467
 None
 0.84A 6b0cD-3v65B:
undetectable		 6b0cD-3v65B:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 ALA B 625
LEU B 627
THR B 604
LEU B 603
ALA B 560
 None
 0.81A 6djzC-3v65B:
undetectable		 6djzC-3v65B:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3v65 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4
(Rattus
norvegicus) 		5 / 12 LEU B 443
ASP B 474
ALA B 495
LEU B 463
LEU B 467
 None
 1.14A 6ew0F-3v65B:
undetectable		 6ew0F-3v65B:
11.53