SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v67 SENSOR PROTEIN CPXA
(Vibrio
parahaemolyticus)
4 / 5 PRO A 144
PRO A 129
ILE A  47
GLY A 141
None
1.17A 2jkjF-3v67A:
undetectable
2jkjF-3v67A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)
3v67 SENSOR PROTEIN CPXA
(Vibrio
parahaemolyticus)
4 / 6 LEU A 147
LEU A 152
ILE A  62
ARG A  59
None
1.05A 2rlfA-3v67A:
undetectable
2rlfB-3v67A:
undetectable
2rlfA-3v67A:
11.97
2rlfB-3v67A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)
3v67 SENSOR PROTEIN CPXA
(Vibrio
parahaemolyticus)
4 / 6 LEU A 147
LEU A 152
ILE A  62
ARG A  59
None
0.96A 2rlfC-3v67A:
undetectable
2rlfD-3v67A:
undetectable
2rlfC-3v67A:
11.97
2rlfD-3v67A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3v67 SENSOR PROTEIN CPXA
(Vibrio
parahaemolyticus)
4 / 7 GLU A  80
ILE A  75
ARG A  59
ILE A  62
None
0.98A 4xumA-3v67A:
undetectable
4xumA-3v67A:
20.07