SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG A 227
THR A 106
VAL A 237
 None
 0.94A 1hxbA-3v68A:
undetectable		 1hxbA-3v68A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		4 / 8 SER A  42
ILE A 170
PHE A   8
VAL A  17
 None
 1.17A 1kb9A-3v68A:
undetectable
1kb9C-3v68A:
undetectable
1kb9D-3v68A:
undetectable
1kb9E-3v68A:
undetectable		 1kb9A-3v68A:
20.28
1kb9C-3v68A:
19.95
1kb9D-3v68A:
20.14
1kb9E-3v68A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ASN A 171
TYR A 224
SER A  34
 None
MPD  A 253 (-4.7A)
None
 0.94A 2gvcB-3v68A:
undetectable		 2gvcB-3v68A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG A 227
THR A 106
VAL A 237
 None
 0.98A 2q64A-3v68A:
undetectable		 2q64A-3v68A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG A 227
THR A 106
VAL A 237
 None
 0.89A 2qakA-3v68A:
undetectable		 2qakA-3v68A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		5 / 12 ILE A 123
GLY A 121
ASN A  38
GLU A  22
ALA A 174
 None
 1.17A 5ih0A-3v68A:
undetectable		 5ih0A-3v68A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pyrococcus
furiosus) 		3 / 3 ARG A 107
PHE A 118
ARG A 227
 None
 1.09A 5y9yA-3v68A:
undetectable		 5y9yA-3v68A:
23.64