SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v6b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3v6b VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2
VEGF-E
(Homo
sapiens;
Orf
virus) 		5 / 10 THR A  43
GLY R 255
ALA R 309
ALA R 248
ILE R 223
 None
 0.94A 1likA-3v6bA:
undetectable		 1likA-3v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3v6b VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2
(Homo
sapiens) 		4 / 6 GLY R 134
GLN R 132
ILE R 215
VAL R 135
 None
 1.09A 3kvvD-3v6bR:
undetectable		 3kvvD-3v6bR:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3v6b VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2
(Homo
sapiens) 		4 / 6 GLY R 134
GLN R 132
ILE R 215
VAL R 135
 None
 1.11A 4e1vF-3v6bR:
undetectable		 4e1vF-3v6bR:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3v6b VEGF-E
(Orf
virus) 		5 / 12 GLY A  85
SER A  86
GLY A  87
ARG A  46
GLU A  41
 None
 0.96A 5c0oH-3v6bA:
undetectable		 5c0oH-3v6bA:
19.92