SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		5 / 9 ILE A 414
LEU A 417
GLU A 361
GLU A 358
ALA A 354
 None
 1.24A 1ctrA-3v71A:
undetectable		 1ctrA-3v71A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		4 / 8 PHE A 348
LEU A 328
ALA A 351
ALA A 347
 None
 0.91A 3ns1L-3v71A:
undetectable		 3ns1L-3v71A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 THR A 154
ALA A 153
LEU A 149
LEU A 161
LEU A 162
 None
 1.27A 4xi3D-3v71A:
undetectable		 4xi3D-3v71A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		4 / 8 HIS A 282
ASP A 324
THR A 321
LEU A 327
 None
 1.02A 5b1bA-3v71A:
undetectable
5b1bC-3v71A:
undetectable
5b1bP-3v71A:
undetectable		 5b1bA-3v71A:
20.92
5b1bC-3v71A:
20.98
5b1bP-3v71A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 GLY A 442
ASP A 447
LEU A 436
ALA A 433
LEU A 382
 None
 0.99A 6bq4A-3v71A:
undetectable		 6bq4A-3v71A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		4 / 8 ARG A 140
ARG A 181
VAL A 150
GLN A 221
 None
 1.16A 6fbvD-3v71A:
2.8		 6fbvD-3v71A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		4 / 7 LEU A 382
ASP A 379
ASP A 376
GLN A 427
 None
 1.25A 6g31D-3v71A:
2.2		 6g31D-3v71A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3v71 PUF (PUMILIO/FBF)
DOMAIN-CONTAINING
PROTEIN 7, CONFIRMED
BY TRANSCRIPT
EVIDENCE
(Caenorhabditis
elegans) 		4 / 6 LEU A 382
ASP A 379
ASP A 376
GLN A 427
 None
 1.29A 6g31J-3v71A:
undetectable		 6g31J-3v71A:
13.45