SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 PHE A 365
LEU A 184
ALA A 357
ILE A 133
ARG A 138
None
1.14A 1crbA-3v76A:
undetectable
1crbA-3v76A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 GLU A 368
THR A 341
TYR A 176
GLY A 173
ALA A 171
FDA  A 547 (-4.1A)
None
None
None
None
1.23A 1httC-3v76A:
undetectable
1httC-3v76A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 GLU A 368
THR A 341
TYR A 176
GLY A 173
ALA A 171
FDA  A 547 (-4.1A)
None
None
None
None
1.25A 1httD-3v76A:
undetectable
1httD-3v76A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 ILE A  11
GLY A 162
ALA A 171
VAL A 366
ALA A  15
None
FDA  A 547 (-3.4A)
None
None
FDA  A 547 (-3.9A)
1.09A 1sg9C-3v76A:
3.5
1sg9C-3v76A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.80A 1usqA-3v76A:
undetectable
1usqA-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.78A 1usqB-3v76A:
undetectable
1usqB-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.81A 1usqC-3v76A:
undetectable
1usqC-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.78A 1usqD-3v76A:
undetectable
1usqD-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.77A 1usqE-3v76A:
undetectable
1usqE-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.77A 1usqF-3v76A:
undetectable
1usqF-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 ASP A 106
GLY A  50
GLY A  49
SER A  47
PHE A  54
None
None
None
FDA  A 547 (-4.4A)
None
1.33A 1w76A-3v76A:
undetectable
1w76A-3v76A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.19A 2f16V-3v76A:
undetectable
2f16W-3v76A:
undetectable
2f16V-3v76A:
19.76
2f16W-3v76A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 LEU A 258
ILE A 254
ALA A 218
VAL A 229
ALA A 216
None
1.26A 2japB-3v76A:
2.5
2japB-3v76A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.76A 2jkjA-3v76A:
undetectable
2jkjA-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.75A 2jkjB-3v76A:
undetectable
2jkjB-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.76A 2jkjC-3v76A:
undetectable
2jkjC-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.74A 2jkjE-3v76A:
undetectable
2jkjE-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.78A 2jklA-3v76A:
undetectable
2jklA-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.79A 2jklB-3v76A:
undetectable
2jklB-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.81A 2jklC-3v76A:
undetectable
2jklC-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.79A 2jklD-3v76A:
undetectable
2jklD-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.78A 2jklE-3v76A:
undetectable
2jklE-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 PRO A  40
GLY A  14
ILE A  10
GLY A  12
None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
0.79A 2jklF-3v76A:
undetectable
2jklF-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 9 LEU A 193
ALA A 240
GLU A 252
GLY A 331
LEU A 196
None
1.13A 2v0mB-3v76A:
undetectable
2v0mB-3v76A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 GLY A 414
GLY A 410
SER A 409
ALA A  75
ALA A  21
None
0.94A 2yvlA-3v76A:
3.1
2yvlA-3v76A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 ALA A 406
PRO A 167
GLY A 163
THR A 172
GLU A 368
FDA  A 547 ( 3.7A)
None
None
FDA  A 547 (-3.1A)
FDA  A 547 (-4.1A)
1.20A 2zifA-3v76A:
undetectable
2zifA-3v76A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 GLY A 162
GLY A 163
GLU A 368
ALA A  16
LEU A 174
FDA  A 547 (-3.4A)
None
FDA  A 547 (-4.1A)
FDA  A 547 (-3.5A)
FDA  A 547 (-3.8A)
1.14A 3ckkA-3v76A:
2.5
3ckkA-3v76A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 ILE A  11
GLY A  12
ASP A  35
ALA A  37
ALA A  16
None
FDA  A 547 (-3.4A)
FDA  A 547 (-3.1A)
FDA  A 547 ( 3.9A)
FDA  A 547 (-3.5A)
0.98A 3jb1A-3v76A:
undetectable
3jb1A-3v76A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.14A 3mg0H-3v76A:
undetectable
3mg0I-3v76A:
undetectable
3mg0H-3v76A:
19.76
3mg0I-3v76A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 THR A 341
SER A 161
ILE A 178
THR A 373
None
FDA  A 547 (-4.8A)
None
None
1.09A 3q70A-3v76A:
undetectable
3q70A-3v76A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 VAL A 159
ALA A 160
GLY A  12
ALA A  24
LEU A 363
None
None
FDA  A 547 (-3.4A)
None
None
1.11A 3qxyA-3v76A:
undetectable
3qxyA-3v76A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 VAL A 159
ALA A 160
GLY A  12
ALA A  24
LEU A 363
None
None
FDA  A 547 (-3.4A)
None
None
1.11A 3rc0A-3v76A:
undetectable
3rc0A-3v76A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 VAL A 159
ALA A 160
GLY A  12
ALA A  24
LEU A 363
None
None
FDA  A 547 (-3.4A)
None
None
1.12A 3rc0B-3v76A:
undetectable
3rc0B-3v76A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
6 / 12 GLY A  17
GLY A 367
ALA A 406
ALA A 408
ALA A  75
SER A  74
None
FDA  A 547 (-3.5A)
FDA  A 547 ( 3.7A)
None
None
None
1.43A 3sudA-3v76A:
undetectable
3sudA-3v76A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 10 MET A 120
GLY A 410
ALA A  24
GLU A  23
VAL A 366
None
0.86A 4da7A-3v76A:
undetectable
4da7A-3v76A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 7 MET A  19
ARG A  27
VAL A 417
MET A 355
None
1.37A 4f4dA-3v76A:
undetectable
4f4dA-3v76A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 4qvpH-3v76A:
undetectable
4qvpI-3v76A:
undetectable
4qvpH-3v76A:
20.00
4qvpI-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.24A 4qvpV-3v76A:
undetectable
4qvpW-3v76A:
undetectable
4qvpV-3v76A:
20.00
4qvpW-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.24A 4qvyV-3v76A:
undetectable
4qvyW-3v76A:
undetectable
4qvyV-3v76A:
20.00
4qvyW-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 4qw0H-3v76A:
undetectable
4qw0I-3v76A:
undetectable
4qw0H-3v76A:
20.00
4qw0I-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.22A 4qw0V-3v76A:
undetectable
4qw0W-3v76A:
undetectable
4qw0V-3v76A:
20.00
4qw0W-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 4qw1H-3v76A:
undetectable
4qw1I-3v76A:
undetectable
4qw1H-3v76A:
20.00
4qw1I-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 4qw1V-3v76A:
undetectable
4qw1W-3v76A:
undetectable
4qw1V-3v76A:
20.00
4qw1W-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 5 GLY A 163
THR A 341
GLY A 344
GLU A 368
None
None
None
FDA  A 547 (-4.1A)
1.18A 4v20A-3v76A:
undetectable
4v20A-3v76A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 9 ALA A 216
GLN A 202
LEU A 198
LEU A 256
LEU A 236
None
1.43A 4x30A-3v76A:
undetectable
4x30A-3v76A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 9 ALA A 240
GLN A 202
LEU A 198
LEU A 256
LEU A 236
None
1.30A 4x30A-3v76A:
undetectable
4x30A-3v76A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.18A 5bxnH-3v76A:
undetectable
5bxnI-3v76A:
undetectable
5bxnH-3v76A:
21.12
5bxnI-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.18A 5bxnV-3v76A:
undetectable
5bxnW-3v76A:
undetectable
5bxnV-3v76A:
21.12
5bxnW-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 5cz7V-3v76A:
undetectable
5cz7W-3v76A:
undetectable
5cz7V-3v76A:
20.00
5cz7W-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 GLU A 368
THR A 341
TYR A 176
GLY A 173
ALA A 171
FDA  A 547 (-4.1A)
None
None
None
None
1.21A 5e3iA-3v76A:
undetectable
5e3iA-3v76A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 11 GLU A 368
THR A 341
TYR A 176
GLY A 173
ALA A 171
FDA  A 547 (-4.1A)
None
None
None
None
1.23A 5e3iB-3v76A:
undetectable
5e3iB-3v76A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 5l5fH-3v76A:
undetectable
5l5fI-3v76A:
undetectable
5l5fH-3v76A:
20.00
5l5fI-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 5l5fV-3v76A:
undetectable
5l5fW-3v76A:
undetectable
5l5fV-3v76A:
20.00
5l5fW-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.22A 5l66H-3v76A:
undetectable
5l66I-3v76A:
undetectable
5l66H-3v76A:
20.00
5l66I-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
5 / 12 THR A 131
ALA A 149
GLY A 150
THR A 151
ASP A 153
None
1.23A 5l66V-3v76A:
undetectable
5l66W-3v76A:
undetectable
5l66V-3v76A:
20.00
5l66W-3v76A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
3v76 FLAVOPROTEIN
(Sinorhizobium
meliloti)
4 / 6 MET A  18
GLY A  12
ALA A  37
LEU A 129
None
FDA  A 547 (-3.4A)
FDA  A 547 ( 3.9A)
None
1.06A 6fosA-3v76A:
undetectable
6fosA-3v76A:
11.17