SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	3v7b	UNCHARACTERIZED PROTEIN (Corynebacterium diphtheriae)	3 / 3	SER A 75 GLU A 76 GLU A 77	None	0.71A	1eqbD-3v7bA: undetectable	1eqbD-3v7bA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3v7b	UNCHARACTERIZED PROTEIN (Corynebacterium diphtheriae)	3 / 3	SER A 75 GLU A 76 GLU A 77	None	0.72A	1eqbB-3v7bA: undetectable	1eqbB-3v7bA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	3v7b	UNCHARACTERIZED PROTEIN (Corynebacterium diphtheriae)	5 / 12	SER A 102 VAL A 116 THR A 52 ILE A 143 HIS A 72	None	1.24A	2vdyA-3v7bA: undetectable	2vdyA-3v7bA: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X2T_I_PEMI202_1 (HEMOGLOBIN SUBUNIT ALPHA HEMOGLOBIN SUBUNIT BETA)	3v7b	UNCHARACTERIZED PROTEIN (Corynebacterium diphtheriae)	4 / 8	PRO A 13 ALA A 63 THR A 67 ALA A 86	None EDO A 401 ( 3.7A) EDO A 401 (-3.5A) None	0.78A	5x2tI-3v7bA: undetectable 5x2tJ-3v7bA: undetectable 5x2tK-3v7bA: undetectable 5x2tL-3v7bA: undetectable	5x2tI-3v7bA: 21.64 5x2tJ-3v7bA: 20.00 5x2tK-3v7bA: 21.64 5x2tL-3v7bA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_FFOA1293_2","SERINE HYDROXYMETHYLTRANSFERASE","3v7b","UNCHARACTERIZED PROTEIN","Corynebacterium diphtheriae",3,"SER A  75;GLU A  76;GLU A  77","None","0.71A","1eqbD-3v7bA:undetectable","1eqbD-3v7bA:19.37"],["1EQB_C_FFOC3293_0","SERINE HYDROXYMETHYLTRANSFERASE","3v7b","UNCHARACTERIZED PROTEIN","Corynebacterium diphtheriae",3,"SER A  75;GLU A  76;GLU A  77","None","0.72A","1eqbB-3v7bA:undetectable","1eqbB-3v7bA:19.37"],["2VDY_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","3v7b","UNCHARACTERIZED PROTEIN","Corynebacterium diphtheriae",5,"SER A 102;VAL A 116;THR A  52;ILE A 143;HIS A  72","None","1.24A","2vdyA-3v7bA:undetectable","2vdyA-3v7bA:18.31"],["5X2T_I_PEMI202_1","HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA;HEMOGLOBIN SUBUNIT ALPHA;HEMOGLOBIN SUBUNIT BETA","3v7b","UNCHARACTERIZED PROTEIN","Corynebacterium diphtheriae",4,"PRO A  13;ALA A  63;THR A  67;ALA A  86","None;EDO A 401 ( 3.7A);EDO A 401 (-3.5A);None","0.78A","5x2tI-3v7bA:undetectable;5x2tJ-3v7bA:undetectable;5x2tK-3v7bA:undetectable;5x2tL-3v7bA:undetectable","5x2tI-3v7bA:21.64;5x2tJ-3v7bA:20.00;5x2tK-3v7bA:21.64;5x2tL-3v7bA:20.00"]]