SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 THR A 158
ASN A 164
CYH A 165
TYR A 160
 None
 1.04A 1dssG-3v85A:
undetectable		 1dssG-3v85A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 LEU A  75
GLU A  89
ALA A  49
LEU A  51
 None
 0.93A 1eta2-3v85A:
undetectable		 1eta2-3v85A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.93A 1v54N-3v85A:
undetectable
1v54W-3v85A:
undetectable		 1v54N-3v85A:
17.05
1v54W-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.89A 1v55A-3v85A:
undetectable
1v55J-3v85A:
undetectable		 1v55A-3v85A:
17.05
1v55J-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.94A 2dyrN-3v85A:
undetectable
2dyrW-3v85A:
undetectable		 2dyrN-3v85A:
17.05
2dyrW-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.92A 2eijN-3v85A:
undetectable
2eijW-3v85A:
undetectable		 2eijN-3v85A:
17.05
2eijW-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.93A 3ablA-3v85A:
undetectable
3ablJ-3v85A:
undetectable		 3ablA-3v85A:
17.05
3ablJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.93A 3ablN-3v85A:
undetectable
3ablW-3v85A:
undetectable		 3ablN-3v85A:
17.05
3ablW-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.87A 3ag3A-3v85A:
undetectable
3ag3J-3v85A:
undetectable		 3ag3A-3v85A:
17.05
3ag3J-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.89A 3ag3N-3v85A:
undetectable
3ag3W-3v85A:
undetectable		 3ag3N-3v85A:
17.05
3ag3W-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		3 / 3 LYS A 200
ILE A 182
PHE A 185
 CIT  A 301 (-2.8A)
None
None
 0.93A 3j7zS-3v85A:
undetectable
3j7za-3v85A:
undetectable		 3j7zS-3v85A:
19.62
3j7za-3v85A:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 LEU A 136
GLY A 137
PHE A  36
PHE A 201
 None
 1.17A 3smtA-3v85A:
undetectable		 3smtA-3v85A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 ARG A  54
LYS A  76
ARG A 143
GLU A   4
 CIT  A 301 (-2.8A)
CIT  A 301 (-2.8A)
CIT  A 301 (-3.0A)
CIT  A 301 ( 3.9A)
 1.39A 3tj7C-3v85A:
18.5		 3tj7C-3v85A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 GLU A   2
ARG A  54
ARG A 143
GLU A   4
 CIT  A 301 ( 4.2A)
CIT  A 301 (-2.8A)
CIT  A 301 (-3.0A)
CIT  A 301 ( 3.9A)
 1.15A 3tj7C-3v85A:
18.5		 3tj7C-3v85A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		5 / 5 GLU A   4
ARG A  54
LYS A  76
ARG A 143
GLU A 169
 CIT  A 301 ( 3.9A)
CIT  A 301 (-2.8A)
CIT  A 301 (-2.8A)
CIT  A 301 (-3.0A)
CIT  A 301 (-2.6A)
 0.81A 3tj7C-3v85A:
18.5		 3tj7C-3v85A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 GLU A  90
GLU A 171
GLU A   4
ARG A 143
 None
None
CIT  A 301 ( 3.9A)
CIT  A 301 (-3.0A)
 1.48A 4r87J-3v85A:
undetectable
4r87L-3v85A:
undetectable		 4r87J-3v85A:
23.00
4r87L-3v85A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 6 LEU A  44
LEU A 118
VAL A 121
PHE A  37
 None
 1.23A 4uswA-3v85A:
undetectable		 4uswA-3v85A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 5 ASP A 129
PHE A 127
PHE A 130
VAL A 121
 None
 1.17A 5a1rA-3v85A:
undetectable		 5a1rA-3v85A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.91A 5b1aA-3v85A:
undetectable
5b1aJ-3v85A:
undetectable		 5b1aA-3v85A:
17.05
5b1aJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.93A 5b1bA-3v85A:
undetectable
5b1bJ-3v85A:
undetectable		 5b1bA-3v85A:
17.05
5b1bJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.92A 5b3sA-3v85A:
undetectable
5b3sJ-3v85A:
undetectable		 5b3sA-3v85A:
17.05
5b3sJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.88A 5iy5A-3v85A:
undetectable
5iy5J-3v85A:
undetectable		 5iy5A-3v85A:
17.05
5iy5J-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.87A 5xdqA-3v85A:
undetectable
5xdqJ-3v85A:
undetectable		 5xdqA-3v85A:
17.05
5xdqJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.87A 5xdqN-3v85A:
undetectable
5xdqW-3v85A:
undetectable		 5xdqN-3v85A:
17.05
5xdqW-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.88A 5xdxA-3v85A:
undetectable
5xdxJ-3v85A:
undetectable		 5xdxA-3v85A:
17.05
5xdxJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.90A 5xdxN-3v85A:
undetectable
5xdxW-3v85A:
undetectable		 5xdxN-3v85A:
17.05
5xdxW-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.90A 5zcpA-3v85A:
undetectable
5zcpJ-3v85A:
undetectable		 5zcpA-3v85A:
17.05
5zcpJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.90A 5zcqA-3v85A:
undetectable
5zcqJ-3v85A:
undetectable		 5zcqA-3v85A:
17.05
5zcqJ-3v85A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3v85 CYTH-LIKE
PHOSPHATASE
(Arabidopsis
thaliana) 		4 / 8 ILE A 191
LEU A 186
THR A  23
LEU A  22
 None
 0.93A 5zcqN-3v85A:
undetectable
5zcqW-3v85A:
undetectable		 5zcqN-3v85A:
17.05
5zcqW-3v85A:
13.33