SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v8b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 MET A  69
ASN A  89
GLN A 164
 None
 0.98A 1xoqB-3v8bA:
undetectable		 1xoqB-3v8bA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 4 LEU A  59
PRO A   6
ILE A  10
LEU A   9
 None
 1.15A 1ya4C-3v8bA:
4.4		 1ya4C-3v8bA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		6 / 12 VAL A 182
LEU A 171
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.49A 2aw1A-3v8bA:
undetectable		 2aw1A-3v8bA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 234
LEU A  25
GLY A  18
SER A  15
ILE A  17
 None
 1.27A 2e7fA-3v8bA:
undetectable		 2e7fA-3v8bA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 234
LEU A  25
GLY A  18
SER A  15
ILE A  17
 None
 1.26A 2e7fB-3v8bA:
2.1		 2e7fB-3v8bA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 234
LEU A  25
GLY A  18
SER A  15
ILE A  17
 None
 1.24A 2ogyA-3v8bA:
undetectable		 2ogyA-3v8bA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 234
LEU A  25
GLY A  18
SER A  15
ILE A  17
 None
 1.25A 2ogyB-3v8bA:
2.7		 2ogyB-3v8bA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ILE A 234
LEU A  25
GLY A  18
SER A  15
ILE A  17
 None
 1.24A 2ycjA-3v8bA:
2.8		 2ycjA-3v8bA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A  12
GLY A  14
ASP A  62
VAL A  63
VAL A 113
 None
 0.92A 3dmfA-3v8bA:
6.4		 3dmfA-3v8bA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 GLY A 117
VAL A  63
ILE A 111
GLN A 164
 None
 0.76A 3fi0B-3v8bA:
undetectable		 3fi0B-3v8bA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 117
VAL A  63
ILE A 111
GLN A 164
 None
 0.83A 3fi0E-3v8bA:
undetectable		 3fi0E-3v8bA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 GLY A 117
VAL A  63
ILE A 111
GLN A 164
 None
 0.82A 3fi0P-3v8bA:
undetectable		 3fi0P-3v8bA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		3 / 3 PHE A  80
SER A   5
GLN A  55
 None
 0.75A 3smtA-3v8bA:
undetectable		 3smtA-3v8bA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 ALA A 156
THR A 155
ALA A 154
THR A 160
 None
 1.01A 4qw0K-3v8bA:
undetectable		 4qw0K-3v8bA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
ALA A 154
THR A 155
ALA A 156
 None
 1.03A 4qw0K-3v8bA:
undetectable		 4qw0K-3v8bA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 ALA A 156
THR A 155
ALA A 154
THR A 160
 None
 1.01A 4qw0Y-3v8bA:
undetectable		 4qw0Y-3v8bA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 THR A 206
ALA A 154
THR A 155
ALA A 156
 None
 1.03A 4qw0Y-3v8bA:
undetectable		 4qw0Y-3v8bA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 7 ILE A  92
GLY A 117
THR A 121
LEU A  35
 None
 0.93A 4ze3A-3v8bA:
undetectable		 4ze3A-3v8bA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A  22
GLY A  12
GLY A  18
GLY A  16
LEU A  35
 None
 0.77A 5c0oH-3v8bA:
6.6		 5c0oH-3v8bA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.33A 5jn8A-3v8bA:
undetectable		 5jn8A-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.38A 5jn9A-3v8bA:
undetectable		 5jn9A-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.37A 5jn9B-3v8bA:
undetectable		 5jn9B-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.36A 5jn9D-3v8bA:
undetectable		 5jn9D-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.31A 5jnaB-3v8bA:
undetectable		 5jnaB-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.29A 5jnaC-3v8bA:
undetectable		 5jnaC-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.28A 5jnaD-3v8bA:
undetectable		 5jnaD-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 11 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.30A 5jncA-3v8bA:
undetectable		 5jncA-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.36A 5jncB-3v8bA:
undetectable		 5jncB-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.32A 5ku6A-3v8bA:
undetectable		 5ku6A-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		5 / 10 VAL A 182
VAL A 168
LEU A 122
THR A 118
THR A 121
 None
 1.31A 5ku6B-3v8bA:
undetectable		 5ku6B-3v8bA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A   8
ILE A 137
ALA A 136
LEU A 129
 None
 0.76A 5te8B-3v8bA:
undetectable		 5te8B-3v8bA:
19.96