SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P91_A_SAMA1401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A)	3v8i	DOPAMINE N ACETYLTRANSFERASE, ISOFORM A (Drosophila melanogaster)	5 / 11	GLY A 159 GLY A 156 ILE A 24 TYR A 75 LEU A 69	None EPE A 301 ( 4.1A) None None None	1.13A	1p91A-3v8iA: undetectable	1p91A-3v8iA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUH_A_CAMA422_0 (CAMPHOR 5-MONOOXYGENASE)	3v8i	DOPAMINE N ACETYLTRANSFERASE, ISOFORM A (Drosophila melanogaster)	4 / 6	THR A 162 LEU A 193 VAL A 189 VAL A 148	None None None EPE A 301 (-4.3A)	1.02A	2zuhA-3v8iA: undetectable	2zuhA-3v8iA: 19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0S_A_PX9A201_0 (BETA-LACTOGLOBULIN)	3v8i	DOPAMINE N ACETYLTRANSFERASE, ISOFORM A (Drosophila melanogaster)	5 / 12	VAL A 78 LEU A 89 LEU A 69 ILE A 27 LEU A 39	None	0.99A	4y0sA-3v8iA: undetectable	4y0sA-3v8iA: 21.97