SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 6 PHE A 403
LEU A 385
VAL A 410
GLN A 408
None
1.14A 1e7aB-3v8uA:
undetectable
1e7aB-3v8uA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 6 GLY A 319
GLY A  41
TYR A  40
SER A 317
None
0.95A 1eswA-3v8uA:
undetectable
1eswA-3v8uA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 10 LEU A 333
SER A 315
PHE A 332
PHE A 217
ILE A 165
None
0.97A 1g5yC-3v8uA:
undetectable
1g5yC-3v8uA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.90A 1p7lC-3v8uA:
undetectable
1p7lC-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.91A 1p7lD-3v8uA:
undetectable
1p7lD-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.91A 1rg9A-3v8uA:
undetectable
1rg9A-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.90A 1rg9B-3v8uA:
undetectable
1rg9B-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.90A 1rg9C-3v8uA:
undetectable
1rg9C-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.90A 1rg9D-3v8uA:
undetectable
1rg9D-3v8uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 TYR A 103
PHE A 166
HIS A 168
GLY A 169
None
0.78A 2ha4A-3v8uA:
undetectable
2ha4A-3v8uA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 VAL A  60
THR A 194
THR A 192
ASP A  66
None
1.26A 2kotB-3v8uA:
undetectable
2kotB-3v8uA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.91A 2obvA-3v8uA:
undetectable
2obvA-3v8uA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.87A 2p02A-3v8uA:
undetectable
2p02A-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
3 / 3 VAL A 152
ASN A  50
TRP A  51
None
0.75A 2y00B-3v8uA:
undetectable
2y00B-3v8uA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 GLU A 654
ALA A 652
GLY A 649
LEU A 493
GLY A 646
None
0.92A 3g2oB-3v8uA:
undetectable
3g2oB-3v8uA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 6 GLY A 241
VAL A 187
HIS A 189
THR A 243
None
1.03A 3tj7A-3v8uA:
undetectable
3tj7B-3v8uA:
undetectable
3tj7A-3v8uA:
14.63
3tj7B-3v8uA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 6 VAL A 187
HIS A 189
THR A 243
GLY A 241
None
1.04A 3tj7C-3v8uA:
undetectable
3tj7D-3v8uA:
2.3
3tj7C-3v8uA:
14.63
3tj7D-3v8uA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
3 / 3 PHE A 166
SER A 101
SER A 100
None
1.02A 3ufgB-3v8uA:
undetectable
3ufgB-3v8uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 11 HIS A 168
GLY A  71
PRO A 172
PHE A 403
GLY A 319
None
1.47A 3v3nA-3v8uA:
undetectable
3v3nA-3v8uA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 SER A 173
GLY A 322
GLY A 329
GLY A 319
GLY A 325
None
0.81A 4ctkC-3v8uA:
undetectable
4ctkC-3v8uA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
3 / 3 LYS A  84
LYS A  81
PRO A  80
None
1.24A 4dv1L-3v8uA:
undetectable
4dv1L-3v8uA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.95A 4kttA-3v8uA:
undetectable
4kttA-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.96A 4kttC-3v8uA:
undetectable
4kttC-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 GLY A 684
GLY A 657
ALA A 576
TYR A 547
GLU A 653
None
1.04A 4lg1A-3v8uA:
undetectable
4lg1A-3v8uA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 GLY A 684
GLY A 657
ALA A 576
TYR A 547
GLU A 653
None
1.04A 4lg1B-3v8uA:
undetectable
4lg1B-3v8uA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 5 THR A 243
PHE A 132
ASN A 124
TYR A 103
None
1.50A 4mf6A-3v8uA:
undetectable
4mf6A-3v8uA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 SER A 137
SER A 344
TYR A 103
GLU A 327
None
1.20A 4ms4A-3v8uA:
undetectable
4ms4A-3v8uA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.93A 4ndnA-3v8uA:
undetectable
4ndnA-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 7 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.92A 4ndnC-3v8uA:
undetectable
4ndnC-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 7 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.84A 4odjA-3v8uA:
undetectable
4odjA-3v8uA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 ASP A 401
PHE A 403
PHE A  42
PHE A 321
GLY A 319
None
1.22A 4pevC-3v8uA:
undetectable
4pevC-3v8uA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.84A 5a1iA-3v8uA:
undetectable
5a1iA-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 7 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.84A 5a1iA-3v8uA:
undetectable
5a1iA-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 6 GLU A 577
GLY A 531
ASP A 386
ARG A 533
None
0.88A 5cdnA-3v8uA:
undetectable
5cdnB-3v8uA:
undetectable
5cdnA-3v8uA:
21.27
5cdnB-3v8uA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 SER A 173
GLY A 322
GLY A 329
GLY A 319
GLY A 325
None
0.84A 5ec8A-3v8uA:
undetectable
5ec8A-3v8uA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 GLY A 656
LEU A 529
GLN A 175
GLY A 531
LEU A 655
None
1.14A 5hg0A-3v8uA:
undetectable
5hg0A-3v8uA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
5 / 12 GLY A 180
LYS A 253
GLU A 280
LEU A 255
GLU A 247
None
1.13A 5nwvA-3v8uA:
undetectable
5nwvA-3v8uA:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.87A 5t8sB-3v8uA:
undetectable
5t8sB-3v8uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 4 SER A 550
THR A 600
ASP A 624
ASP A 594
None
1.45A 5vimA-3v8uA:
undetectable
5vimA-3v8uA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 GLU A  64
PHE A 166
SER A 344
LEU A 104
None
1.10A 5y2tB-3v8uA:
undetectable
5y2tB-3v8uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 7 PHE A 683
ALA A 567
GLY A 553
THR A 441
None
0.71A 5ybbB-3v8uA:
undetectable
5ybbB-3v8uA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.87A 6fbnB-3v8uA:
undetectable
6fbnB-3v8uA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.84A 6fboA-3v8uA:
undetectable
6fboA-3v8uA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.90A 6fcbA-3v8uA:
undetectable
6fcbA-3v8uA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 8 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.85A 6fcdA-3v8uA:
undetectable
6fcdA-3v8uA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
3v8u TRANSFERRIN
BINDING-PROTEIN B

(Neisseria
meningitidis)
4 / 7 HIS A 143
ASP A 161
PHE A 217
ASP A 221
None
0.84A 6g6rA-3v8uA:
undetectable
6g6rA-3v8uA:
19.81