SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A52_A_ESTA1_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.35A	1a52A-3v8vA: undetectable	1a52A-3v8vA: 16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A52_B_ESTB2_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.37A	1a52B-3v8vA: undetectable	1a52B-3v8vA: 16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CMA_B_SAMB105_0 (PROTEIN (MET REPRESSOR))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 11	LEU A 16 GLU A 19 LEU A 23 ALA A 25 GLY A 39	None	1.19A	1cmaA-3v8vA: undetectable 1cmaB-3v8vA: undetectable	1cmaA-3v8vA: 12.77 1cmaB-3v8vA: 12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CMC_B_SAMB105_0 (MET REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	LEU A 16 GLU A 19 LEU A 23 ALA A 25 GLY A 39	None	1.18A	1cmcA-3v8vA: undetectable 1cmcB-3v8vA: undetectable	1cmcA-3v8vA: 12.77 1cmcB-3v8vA: 12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DBB_H_STRH229_1 (IGG1-KAPPA DB3 FAB (HEAVY CHAIN) IGG1-KAPPA DB3 FAB (LIGHT CHAIN))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 8	ASN A 580 TRP A 576 GLY A 550 TYR A 548 VAL A 503	None None None SAM A 802 (-4.7A) None	1.35A	1dbbH-3v8vA: undetectable 1dbbL-3v8vA: undetectable	1dbbH-3v8vA: 14.06 1dbbL-3v8vA: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVX_B_DIFB125_1 (TRANSTHYRETIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 7	LEU A 307 ALA A 207 LEU A 203 SER A 200	None None SAM A 801 ( 4.7A) SAM A 801 (-3.0A)	0.93A	1dvxA-3v8vA: undetectable	1dvxA-3v8vA: 11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EPB_A_9CRA165_1 (EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	6 / 12	PHE A 95 ILE A 102 VAL A 66 VAL A 141 ILE A 150 ILE A 79	None	1.16A	1epbA-3v8vA: undetectable	1epbA-3v8vA: 13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EPB_B_9CRB165_1 (EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PHE A 95 ILE A 102 VAL A 66 ILE A 150 ILE A 79	None	0.99A	1epbB-3v8vA: undetectable	1epbB-3v8vA: 13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_A_ESTA600_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 9	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.40A	1ereA-3v8vA: undetectable	1ereA-3v8vA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_B_ESTB600_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 9	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.41A	1ereB-3v8vA: undetectable	1ereB-3v8vA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_C_ESTC600_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 9	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.40A	1ereC-3v8vA: undetectable	1ereC-3v8vA: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G60_A_SAMA500_0 (ADENINE-SPECIFIC METHYLTRANSFERASE MBOIIA)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	CYH A 598 ASP A 615 PHE A 546 MET A 569 TYR A 573	SAM A 802 (-3.3A) None SAM A 802 (-4.5A) SAM A 802 (-3.2A) SAM A 802 (-4.6A)	1.45A	1g60A-3v8vA: 3.8	1g60A-3v8vA: 16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2200_0 (PROTEIN (METHIONINE REPRESSOR))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ALA A 25 GLY A 39 LEU A 16 GLU A 19 LEU A 23	None	1.20A	1mj2A-3v8vA: undetectable 1mj2B-3v8vA: undetectable	1mj2A-3v8vA: 13.17 1mj2B-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC2199_0 (PROTEIN (METHIONINE REPRESSOR))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ALA A 25 GLY A 39 LEU A 16 GLU A 19 LEU A 23	None	1.15A	1mj2C-3v8vA: undetectable 1mj2D-3v8vA: undetectable	1mj2C-3v8vA: 13.17 1mj2D-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_A_SAMA200_0 (METHIONINE REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 11	LEU A 16 GLU A 19 LEU A 23 ALA A 25 GLY A 39	None	1.16A	1mjqA-3v8vA: undetectable 1mjqB-3v8vA: undetectable	1mjqA-3v8vA: 13.17 1mjqB-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_C_SAMC199_0 (METHIONINE REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	LEU A 16 GLU A 19 LEU A 23 ALA A 25 GLY A 39	None	1.16A	1mjqC-3v8vA: undetectable 1mjqD-3v8vA: undetectable	1mjqC-3v8vA: 13.17 1mjqD-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_D_SAMD200_0 (METHIONINE REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ALA A 25 GLY A 39 LEU A 16 GLU A 19 LEU A 23	None	1.11A	1mjqC-3v8vA: undetectable 1mjqD-3v8vA: undetectable	1mjqC-3v8vA: 13.17 1mjqD-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_I_SAMI199_0 (METHIONINE REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 11	LEU A 16 GLU A 19 LEU A 23 ALA A 25 GLY A 39	None	1.16A	1mjqI-3v8vA: undetectable 1mjqJ-3v8vA: undetectable	1mjqI-3v8vA: 13.17 1mjqJ-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_J_SAMJ200_0 (METHIONINE REPRESSOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ALA A 25 GLY A 39 LEU A 16 GLU A 19 LEU A 23	None	1.12A	1mjqI-3v8vA: undetectable 1mjqJ-3v8vA: undetectable	1mjqI-3v8vA: 13.17 1mjqJ-3v8vA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_E_THAE5_1 (LIVER CARBOXYLESTERASE I)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	LEU A 204 GLY A 260 LEU A 329 MET A 333 PHE A 337	None	1.24A	1mx1E-3v8vA: undetectable	1mx1E-3v8vA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QAO_A_SAMA245_0 (ERMC' METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 ASP A 264 ASP A 290 ASN A 309 PRO A 311	SAM A 801 (-3.2A) None SAM A 801 (-3.0A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A)	0.64A	1qaoA-3v8vA: 13.3	1qaoA-3v8vA: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QHY_A_CLMA888_0 (CHLORAMPHENICOL PHOSPHOTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 6	PRO A 172 ALA A 178 GLU A 206 GLU A 175	SAM A 801 ( 4.7A) None None None	1.37A	1qhyA-3v8vA: undetectable	1qhyA-3v8vA: 12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA11_1 (CES1 PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 8	PRO A 310 LEU A 329 GLY A 330 LEU A 344	None	0.92A	1ya4A-3v8vA: undetectable	1ya4A-3v8vA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_G_BEZG3385_0 (CES1 PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	SER A 261 VAL A 306 LEU A 194	None	0.74A	1yajG-3v8vA: undetectable	1yajG-3v8vA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1O_A_CAMA1422_0 (CYTOCHROME P450-CAM)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 8	PHE A 225 LEU A 159 GLY A 217 VAL A 239	None	0.89A	2a1oA-3v8vA: undetectable	2a1oA-3v8vA: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	SER A 551 ASP A 568 CYH A 598	None SAM A 802 (-2.9A) SAM A 802 (-3.3A)	0.90A	2br4E-3v8vA: 8.8	2br4E-3v8vA: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	SER A 551 ASP A 615 CYH A 696	None	0.99A	2br4E-3v8vA: 8.8	2br4E-3v8vA: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJT_A_SAMA501_1 (N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ARG A 530 ASP A 568 ASP A 597	None SAM A 802 (-2.9A) SAM A 802 (-3.5A)	0.62A	2ejtA-3v8vA: 14.2	2ejtA-3v8vA: 20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HMY_B_SAMB328_0 (PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 ASP A 264 ASP A 290 PRO A 311 LEU A 325	SAM A 801 (-3.2A) None SAM A 801 (-3.0A) SAM A 801 ( 4.1A) SAM A 801 ( 4.8A)	0.91A	2hmyB-3v8vA: 8.4	2hmyB-3v8vA: 19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_A_SAMA1001_0 (SAM DEPENDENT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PHE A 523 PHE A 546 TYR A 548 SER A 570 PRO A 617	None SAM A 802 (-4.5A) SAM A 802 (-4.7A) None SAM A 802 ( 4.6A)	0.73A	2igtA-3v8vA: 0.0	2igtA-3v8vA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_A_SAMA1001_1 (SAM DEPENDENT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ASP A 568 ASP A 597 ASP A 615	SAM A 802 (-2.9A) SAM A 802 (-3.5A) None	0.58A	2igtA-3v8vA: 22.5	2igtA-3v8vA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_B_SAMB1002_0 (SAM DEPENDENT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PHE A 523 PHE A 546 TYR A 548 SER A 570 PRO A 617	None SAM A 802 (-4.5A) SAM A 802 (-4.7A) None SAM A 802 ( 4.6A)	0.70A	2igtB-3v8vA: 22.4	2igtB-3v8vA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_B_SAMB1002_1 (SAM DEPENDENT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ASP A 568 ASP A 597 ASP A 615	SAM A 802 (-2.9A) SAM A 802 (-3.5A) None	0.63A	2igtB-3v8vA: 10.2	2igtB-3v8vA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IGT_C_SAMC1003_0 (SAM DEPENDENT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PHE A 523 PHE A 546 TYR A 548 SER A 570 PRO A 617	None SAM A 802 (-4.5A) SAM A 802 (-4.7A) None SAM A 802 ( 4.6A)	0.73A	2igtC-3v8vA: 22.3	2igtC-3v8vA: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 195 GLY A 199 LEU A 203 ASP A 264 ASN A 309	None SAM A 801 (-3.2A) SAM A 801 ( 4.7A) None SAM A 801 (-4.5A)	0.72A	2nxeA-3v8vA: 14.4	2nxeA-3v8vA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 195 GLY A 199 LEU A 203 ASP A 264 ASN A 309	None SAM A 801 (-3.2A) SAM A 801 ( 4.7A) None SAM A 801 (-4.5A)	0.72A	2nxeB-3v8vA: 14.4	2nxeB-3v8vA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 LEU A 203 VAL A 291 ASN A 309 PRO A 311	SAM A 801 (-3.2A) SAM A 801 ( 4.7A) SAM A 801 (-3.8A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A)	0.58A	2zulA-3v8vA: 15.8	2zulA-3v8vA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 SER A 200 LEU A 203 ASP A 264 ASN A 309	SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 ( 4.7A) None SAM A 801 (-4.5A)	0.66A	3cjtO-3v8vA: 14.3	3cjtO-3v8vA: 17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMF_A_SAMA388_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 ASP A 290 VAL A 291 ASN A 309 PRO A 311	SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-3.8A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A)	0.66A	3dmfA-3v8vA: 15.8	3dmfA-3v8vA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	GLY A 199 LEU A 203 VAL A 291 ASN A 309 PRO A 311	SAM A 801 (-3.2A) SAM A 801 ( 4.7A) SAM A 801 (-3.8A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A)	0.55A	3dmhA-3v8vA: 13.3	3dmhA-3v8vA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DOU_A_SAMA1_1 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ASP A 568 ASP A 597 ASP A 615	SAM A 802 (-2.9A) SAM A 802 (-3.5A) None	0.78A	3douA-3v8vA: 11.1	3douA-3v8vA: 14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MEG_A_T27A561_1 (P66 REVERSE TRANSCRIPTASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PRO A 310 LEU A 329 VAL A 379 VAL A 306 TYR A 377	None	1.40A	3megA-3v8vA: undetectable	3megA-3v8vA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TM4_A_SAMA401_0 (TRNA (GUANINE N2-)-METHYLTRANSFERA SE TRM14)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	MET A 197 GLY A 199 ASN A 309 PRO A 311 LEU A 325	SAM A 801 (-4.5A) SAM A 801 (-3.2A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A) SAM A 801 ( 4.8A)	0.50A	3tm4A-3v8vA: 31.0	3tm4A-3v8vA: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TM4_B_SAMB401_0 (TRNA (GUANINE N2-)-METHYLTRANSFERA SE TRM14)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	MET A 197 GLY A 199 ASN A 309 PRO A 311 LEU A 325	SAM A 801 (-4.5A) SAM A 801 (-3.2A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A) SAM A 801 ( 4.8A)	0.52A	3tm4B-3v8vA: 31.2	3tm4B-3v8vA: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UT5_B_LOCB502_1 (TUBULIN BETA CHAIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	LEU A 43 LEU A 20 THR A 8 ALA A 6 ILE A 57	None	1.15A	3ut5B-3v8vA: 3.7	3ut5B-3v8vA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UUD_B_ESTB600_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.36A	3uudB-3v8vA: undetectable	3uudB-3v8vA: 16.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_A_SAMA801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	12 / 12	PRO A 172 ILE A 173 MET A 197 GLY A 199 SER A 200 THR A 202 SER A 263 ASP A 264 VAL A 291 ASN A 309 PRO A 311 LEU A 325	SAM A 801 ( 4.7A) SAM A 801 ( 4.9A) SAM A 801 (-4.5A) SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-4.1A) SAM A 801 (-3.5A) None SAM A 801 (-3.8A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A) SAM A 801 ( 4.8A)	0.00A	3v8vA-3v8vA: 62.9	3v8vA-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_A_SAMA801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	8 / 12	PRO A 172 ILE A 173 SER A 200 THR A 202 ASP A 264 ASN A 309 PRO A 311 LEU A 322	SAM A 801 ( 4.7A) SAM A 801 ( 4.9A) SAM A 801 (-3.0A) SAM A 801 (-4.1A) None SAM A 801 (-4.5A) SAM A 801 ( 4.1A) None	1.46A	3v8vA-3v8vA: 62.9	3v8vA-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_A_SAMA802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 9	PHE A 546 TYR A 548 ASP A 568 CYH A 598 PRO A 616	SAM A 802 (-4.5A) SAM A 802 (-4.7A) SAM A 802 (-2.9A) SAM A 802 (-3.3A) None	1.39A	3v8vA-3v8vA: 62.9	3v8vA-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_A_SAMA802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	9 / 9	PHE A 546 TYR A 548 ASP A 568 MET A 569 SER A 570 TYR A 573 ASP A 597 CYH A 598 PRO A 617	SAM A 802 (-4.5A) SAM A 802 (-4.7A) SAM A 802 (-2.9A) SAM A 802 (-3.2A) None SAM A 802 (-4.6A) SAM A 802 (-3.5A) SAM A 802 (-3.3A) SAM A 802 ( 4.6A)	0.01A	3v8vA-3v8vA: 62.9	3v8vA-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_B_SAMB801_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	11 / 11	MET A 197 GLY A 199 ASP A 262 SER A 263 ASP A 264 ASP A 290 VAL A 291 ASN A 309 PRO A 311 TYR A 312 LEU A 325	SAM A 801 (-4.5A) SAM A 801 (-3.2A) SAM A 801 (-2.9A) SAM A 801 (-3.5A) None SAM A 801 (-3.0A) SAM A 801 (-3.8A) SAM A 801 (-4.5A) SAM A 801 ( 4.1A) None SAM A 801 ( 4.8A)	0.34A	3v8vB-3v8vA: 51.5	3v8vB-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_B_SAMB802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	6 / 12	ARG A 530 PHE A 546 SER A 551 ASP A 597 CYH A 598 PRO A 616	None SAM A 802 (-4.5A) None SAM A 802 (-3.5A) SAM A 802 (-3.3A) None	1.43A	3v8vB-3v8vA: 51.5	3v8vB-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_B_SAMB802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	11 / 12	ARG A 530 PHE A 546 TYR A 548 SER A 551 MET A 569 SER A 570 TYR A 573 ASP A 597 CYH A 598 ASP A 615 PRO A 617	None SAM A 802 (-4.5A) SAM A 802 (-4.7A) None SAM A 802 (-3.2A) None SAM A 802 (-4.6A) SAM A 802 (-3.5A) SAM A 802 (-3.3A) None SAM A 802 ( 4.6A)	0.30A	3v8vB-3v8vA: 51.5	3v8vB-3v8vA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3V8V_B_SAMB802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PHE A 546 TYR A 548 ASP A 597 CYH A 598 PRO A 617	SAM A 802 (-4.5A) SAM A 802 (-4.7A) SAM A 802 (-3.5A) SAM A 802 (-3.3A) SAM A 802 ( 4.6A)	1.10A	3v8vB-3v8vA: 51.5	3v8vB-3v8vA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DMG_A_SAMA401_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ARG A 530 TYR A 548 ASP A 568 ASP A 615 PRO A 617	None SAM A 802 (-4.7A) SAM A 802 (-2.9A) None SAM A 802 ( 4.6A)	0.58A	4dmgA-3v8vA: 24.2	4dmgA-3v8vA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DMG_B_SAMB401_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 11	ARG A 530 TYR A 548 ASP A 568 ASP A 615 PRO A 617	None SAM A 802 (-4.7A) SAM A 802 (-2.9A) None SAM A 802 ( 4.6A)	0.58A	4dmgB-3v8vA: 24.5	4dmgB-3v8vA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_J_KANJ301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 6	ASP A 433 ASP A 422 ASN A 690 ASP A 686	None	1.26A	4gkhJ-3v8vA: undetectable	4gkhJ-3v8vA: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_J_SASJ804_1 (SEPIAPTERIN REDUCTASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	LEU A 543 LEU A 599 CYH A 598 PHE A 546 ASP A 615	None None SAM A 802 (-3.3A) SAM A 802 (-4.5A) None	1.31A	4j7xJ-3v8vA: 6.7	4j7xJ-3v8vA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JUO_F_LFXF101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 4	SER A 226 GLY A 217 GLU A 175	None	0.53A	4juoA-3v8vA: undetectable 4juoC-3v8vA: undetectable	4juoA-3v8vA: 22.98 4juoC-3v8vA: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_D_SAMD601_1 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ASN A 690 ASP A 525 ASP A 519	None	0.88A	4obwD-3v8vA: 12.8	4obwD-3v8vA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_D_LOCD502_1 (TUBULIN BETA CHAIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	LEU A 43 LEU A 20 THR A 8 ALA A 6 ILE A 57	None	1.13A	4x1iD-3v8vA: 3.4	4x1iD-3v8vA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X20_D_LOCD502_2 (TUBULIN BETA CHAIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 11	LEU A 43 LEU A 20 THR A 8 ALA A 6 ILE A 57	None	1.17A	4x20D-3v8vA: 3.5	4x20D-3v8vA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XMF_A_HSMA202_1 (NITROPHORIN-7)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	3 / 3	ASP A 153 LEU A 159 GLY A 158	None	0.44A	4xmfA-3v8vA: undetectable	4xmfA-3v8vA: 13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_1 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 4	ASP A 195 GLY A 199 ASP A 262 ASP A 290	None SAM A 801 (-3.2A) SAM A 801 (-2.9A) SAM A 801 (-3.0A)	0.47A	5e72A-3v8vA: 17.8	5e72A-3v8vA: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_A_SAMA301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 290 PRO A 311 GLY A 199 THR A 202 SER A 263	SAM A 801 (-3.0A) SAM A 801 ( 4.1A) SAM A 801 (-3.2A) SAM A 801 (-4.1A) SAM A 801 (-3.5A)	0.73A	5hfjA-3v8vA: 2.6	5hfjA-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_B_SAMB301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	PRO A 311 GLY A 199 SER A 200 THR A 202 SER A 263	SAM A 801 ( 4.1A) SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-4.1A) SAM A 801 (-3.5A)	0.64A	5hfjB-3v8vA: 2.7	5hfjB-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_C_SAMC301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 290 PRO A 311 GLY A 199 THR A 202 SER A 263	SAM A 801 (-3.0A) SAM A 801 ( 4.1A) SAM A 801 (-3.2A) SAM A 801 (-4.1A) SAM A 801 (-3.5A)	0.69A	5hfjC-3v8vA: 3.8	5hfjC-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_D_SAMD301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	6 / 12	ASP A 290 PRO A 311 GLY A 199 SER A 200 THR A 202 SER A 263	SAM A 801 (-3.0A) SAM A 801 ( 4.1A) SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-4.1A) SAM A 801 (-3.5A)	0.62A	5hfjD-3v8vA: 3.6	5hfjD-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_E_SAME301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 290 GLY A 199 SER A 200 THR A 202 SER A 263	SAM A 801 (-3.0A) SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-4.1A) SAM A 801 (-3.5A)	0.61A	5hfjE-3v8vA: 3.5	5hfjE-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_F_SAMF301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 290 PRO A 311 GLY A 199 SER A 200 SER A 263	SAM A 801 (-3.0A) SAM A 801 ( 4.1A) SAM A 801 (-3.2A) SAM A 801 (-3.0A) SAM A 801 (-3.5A)	0.80A	5hfjF-3v8vA: 4.0	5hfjF-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_H_SAMH301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	ASP A 597 ASP A 615 PRO A 617 PHE A 546 TYR A 573	SAM A 802 (-3.5A) None SAM A 802 ( 4.6A) SAM A 802 (-4.5A) SAM A 802 (-4.6A)	0.94A	5hfjH-3v8vA: 4.7	5hfjH-3v8vA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HYR_A_ESTA601_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 10	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.37A	5hyrA-3v8vA: undetectable	5hyrA-3v8vA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MIO_B_LOCB502_1 (TUBULIN BETA CHAIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 12	LEU A 43 LEU A 20 THR A 8 ALA A 6 ILE A 57	None	1.09A	5mioB-3v8vA: 3.5	5mioB-3v8vA: 20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA309_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 4	LEU A 16 GLY A 34 SER A 7 SER A 55	None	1.29A	5uunA-3v8vA: undetectable	5uunA-3v8vA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB306_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 4	LEU A 16 GLY A 34 SER A 7 SER A 55	None	1.30A	5uunB-3v8vA: undetectable	5uunB-3v8vA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WGD_A_ESTA601_1 (ESTROGEN RECEPTOR)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	5 / 9	ALA A 6 LEU A 16 LEU A 12 HIS A 160 LEU A 159	None	1.34A	5wgdA-3v8vA: undetectable	5wgdA-3v8vA: 8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_2 (ADENOSYLHOMOCYSTEINA SE)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 5	THR A 651 THR A 682 HIS A 526 LEU A 533	None	1.44A	6aphA-3v8vA: 5.0	6aphA-3v8vA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DCH_A_ACTA401_0 (SCOE PROTEIN)	3v8v	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L (Escherichia coli)	4 / 5	THR A 679 HIS A 526 ASP A 615 HIS A 694	None	1.43A	6dchA-3v8vA: undetectable	6dchA-3v8vA: 18.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A52_A_ESTA1_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.35A","1a52A-3v8vA:undetectable","1a52A-3v8vA:16.93"],["1A52_B_ESTB2_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.37A","1a52B-3v8vA:undetectable","1a52B-3v8vA:16.93"],["1CMA_B_SAMB105_0","PROTEIN (MET REPRESSOR)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  16;GLU A  19;LEU A  23;ALA A  25;GLY A  39","None","1.19A","1cmaA-3v8vA:undetectable;1cmaB-3v8vA:undetectable","1cmaA-3v8vA:12.77;1cmaB-3v8vA:12.77"],["1CMC_B_SAMB105_0","MET REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  16;GLU A  19;LEU A  23;ALA A  25;GLY A  39","None","1.18A","1cmcA-3v8vA:undetectable;1cmcB-3v8vA:undetectable","1cmcA-3v8vA:12.77;1cmcB-3v8vA:12.77"],["1DBB_H_STRH229_1","IGG1-KAPPA DB3 FAB (HEAVY CHAIN);IGG1-KAPPA DB3 FAB (LIGHT CHAIN)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASN A 580;TRP A 576;GLY A 550;TYR A 548;VAL A 503","None;None;None;SAM A 802 (-4.7A);None","1.35A","1dbbH-3v8vA:undetectable;1dbbL-3v8vA:undetectable","1dbbH-3v8vA:14.06;1dbbL-3v8vA:16.21"],["1DVX_B_DIFB125_1","TRANSTHYRETIN;TRANSTHYRETIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"LEU A 307;ALA A 207;LEU A 203;SER A 200","None;None;SAM A 801 ( 4.7A);SAM A 801 (-3.0A)","0.93A","1dvxA-3v8vA:undetectable","1dvxA-3v8vA:11.74"],["1EPB_A_9CRA165_1","EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",6,"PHE A  95;ILE A 102;VAL A  66;VAL A 141;ILE A 150;ILE A  79","None","1.16A","1epbA-3v8vA:undetectable","1epbA-3v8vA:13.42"],["1EPB_B_9CRB165_1","EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A  95;ILE A 102;VAL A  66;ILE A 150;ILE A  79","None","0.99A","1epbB-3v8vA:undetectable","1epbB-3v8vA:13.42"],["1ERE_A_ESTA600_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.40A","1ereA-3v8vA:undetectable","1ereA-3v8vA:16.46"],["1ERE_B_ESTB600_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.41A","1ereB-3v8vA:undetectable","1ereB-3v8vA:16.46"],["1ERE_C_ESTC600_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.40A","1ereC-3v8vA:undetectable","1ereC-3v8vA:16.46"],["1G60_A_SAMA500_0","ADENINE-SPECIFIC METHYLTRANSFERASE MBOIIA","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"CYH A 598;ASP A 615;PHE A 546;MET A 569;TYR A 573","SAM A 802 (-3.3A);None;SAM A 802 (-4.5A);SAM A 802 (-3.2A);SAM A 802 (-4.6A)","1.45A","1g60A-3v8vA:3.8","1g60A-3v8vA:16.07"],["1MJ2_A_SAMA2200_0","PROTEIN (METHIONINE REPRESSOR)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A  25;GLY A  39;LEU A  16;GLU A  19;LEU A  23","None","1.20A","1mj2A-3v8vA:undetectable;1mj2B-3v8vA:undetectable","1mj2A-3v8vA:13.17;1mj2B-3v8vA:13.17"],["1MJ2_C_SAMC2199_0","PROTEIN (METHIONINE REPRESSOR)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A  25;GLY A  39;LEU A  16;GLU A  19;LEU A  23","None","1.15A","1mj2C-3v8vA:undetectable;1mj2D-3v8vA:undetectable","1mj2C-3v8vA:13.17;1mj2D-3v8vA:13.17"],["1MJQ_A_SAMA200_0","METHIONINE REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  16;GLU A  19;LEU A  23;ALA A  25;GLY A  39","None","1.16A","1mjqA-3v8vA:undetectable;1mjqB-3v8vA:undetectable","1mjqA-3v8vA:13.17;1mjqB-3v8vA:13.17"],["1MJQ_C_SAMC199_0","METHIONINE REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  16;GLU A  19;LEU A  23;ALA A  25;GLY A  39","None","1.16A","1mjqC-3v8vA:undetectable;1mjqD-3v8vA:undetectable","1mjqC-3v8vA:13.17;1mjqD-3v8vA:13.17"],["1MJQ_D_SAMD200_0","METHIONINE REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A  25;GLY A  39;LEU A  16;GLU A  19;LEU A  23","None","1.11A","1mjqC-3v8vA:undetectable;1mjqD-3v8vA:undetectable","1mjqC-3v8vA:13.17;1mjqD-3v8vA:13.17"],["1MJQ_I_SAMI199_0","METHIONINE REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  16;GLU A  19;LEU A  23;ALA A  25;GLY A  39","None","1.16A","1mjqI-3v8vA:undetectable;1mjqJ-3v8vA:undetectable","1mjqI-3v8vA:13.17;1mjqJ-3v8vA:13.17"],["1MJQ_J_SAMJ200_0","METHIONINE REPRESSOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A  25;GLY A  39;LEU A  16;GLU A  19;LEU A  23","None","1.12A","1mjqI-3v8vA:undetectable;1mjqJ-3v8vA:undetectable","1mjqI-3v8vA:13.17;1mjqJ-3v8vA:13.17"],["1MX1_E_THAE5_1","LIVER CARBOXYLESTERASE I","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A 204;GLY A 260;LEU A 329;MET A 333;PHE A 337","None","1.24A","1mx1E-3v8vA:undetectable","1mx1E-3v8vA:22.34"],["1QAO_A_SAMA245_0","ERMC' METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;ASP A 264;ASP A 290;ASN A 309;PRO A 311","SAM A 801 (-3.2A);None;SAM A 801 (-3.0A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A)","0.64A","1qaoA-3v8vA:13.3","1qaoA-3v8vA:16.47"],["1QHY_A_CLMA888_0","CHLORAMPHENICOL PHOSPHOTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"PRO A 172;ALA A 178;GLU A 206;GLU A 175","SAM A 801 ( 4.7A);None;None;None","1.37A","1qhyA-3v8vA:undetectable","1qhyA-3v8vA:12.52"],["1YA4_A_CTXA11_1","CES1 PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"PRO A 310;LEU A 329;GLY A 330;LEU A 344","None","0.92A","1ya4A-3v8vA:undetectable","1ya4A-3v8vA:22.13"],["1YAJ_G_BEZG3385_0","CES1 PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"SER A 261;VAL A 306;LEU A 194","None","0.74A","1yajG-3v8vA:undetectable","1yajG-3v8vA:22.13"],["2A1O_A_CAMA1422_0","CYTOCHROME P450-CAM","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"PHE A 225;LEU A 159;GLY A 217;VAL A 239","None","0.89A","2a1oA-3v8vA:undetectable","2a1oA-3v8vA:19.86"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"SER A 551;ASP A 568;CYH A 598","None;SAM A 802 (-2.9A);SAM A 802 (-3.3A)","0.90A","2br4E-3v8vA:8.8","2br4E-3v8vA:15.04"],["2BR4_E_SAME301_1","CEPHALOSPORIN HYDROXYLASE CMCI","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"SER A 551;ASP A 615;CYH A 696","None","0.99A","2br4E-3v8vA:8.8","2br4E-3v8vA:15.04"],["2EJT_A_SAMA501_1","N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ARG A 530;ASP A 568;ASP A 597","None;SAM A 802 (-2.9A);SAM A 802 (-3.5A)","0.62A","2ejtA-3v8vA:14.2","2ejtA-3v8vA:20.76"],["2HMY_B_SAMB328_0","PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;ASP A 264;ASP A 290;PRO A 311;LEU A 325","SAM A 801 (-3.2A);None;SAM A 801 (-3.0A);SAM A 801 ( 4.1A);SAM A 801 ( 4.8A)","0.91A","2hmyB-3v8vA:8.4","2hmyB-3v8vA:19.03"],["2IGT_A_SAMA1001_0","SAM DEPENDENT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A 523;PHE A 546;TYR A 548;SER A 570;PRO A 617","None;SAM A 802 (-4.5A);SAM A 802 (-4.7A);None;SAM A 802 ( 4.6A)","0.73A","2igtA-3v8vA:0.0","2igtA-3v8vA:18.74"],["2IGT_A_SAMA1001_1","SAM DEPENDENT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ASP A 568;ASP A 597;ASP A 615","SAM A 802 (-2.9A);SAM A 802 (-3.5A);None","0.58A","2igtA-3v8vA:22.5","2igtA-3v8vA:18.74"],["2IGT_B_SAMB1002_0","SAM DEPENDENT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A 523;PHE A 546;TYR A 548;SER A 570;PRO A 617","None;SAM A 802 (-4.5A);SAM A 802 (-4.7A);None;SAM A 802 ( 4.6A)","0.70A","2igtB-3v8vA:22.4","2igtB-3v8vA:18.74"],["2IGT_B_SAMB1002_1","SAM DEPENDENT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ASP A 568;ASP A 597;ASP A 615","SAM A 802 (-2.9A);SAM A 802 (-3.5A);None","0.63A","2igtB-3v8vA:10.2","2igtB-3v8vA:18.74"],["2IGT_C_SAMC1003_0","SAM DEPENDENT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A 523;PHE A 546;TYR A 548;SER A 570;PRO A 617","None;SAM A 802 (-4.5A);SAM A 802 (-4.7A);None;SAM A 802 ( 4.6A)","0.73A","2igtC-3v8vA:22.3","2igtC-3v8vA:18.74"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 195;GLY A 199;LEU A 203;ASP A 264;ASN A 309","None;SAM A 801 (-3.2A);SAM A 801 ( 4.7A);None;SAM A 801 (-4.5A)","0.72A","2nxeA-3v8vA:14.4","2nxeA-3v8vA:18.64"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 195;GLY A 199;LEU A 203;ASP A 264;ASN A 309","None;SAM A 801 (-3.2A);SAM A 801 ( 4.7A);None;SAM A 801 (-4.5A)","0.72A","2nxeB-3v8vA:14.4","2nxeB-3v8vA:18.64"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;LEU A 203;VAL A 291;ASN A 309;PRO A 311","SAM A 801 (-3.2A);SAM A 801 ( 4.7A);SAM A 801 (-3.8A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A)","0.58A","2zulA-3v8vA:15.8","2zulA-3v8vA:22.46"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;SER A 200;LEU A 203;ASP A 264;ASN A 309","SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 ( 4.7A);None;SAM A 801 (-4.5A)","0.66A","3cjtO-3v8vA:14.3","3cjtO-3v8vA:17.95"],["3DMF_A_SAMA388_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;ASP A 290;VAL A 291;ASN A 309;PRO A 311","SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-3.8A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A)","0.66A","3dmfA-3v8vA:15.8","3dmfA-3v8vA:22.41"],["3DMH_A_SAMA384_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"GLY A 199;LEU A 203;VAL A 291;ASN A 309;PRO A 311","SAM A 801 (-3.2A);SAM A 801 ( 4.7A);SAM A 801 (-3.8A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A)","0.55A","3dmhA-3v8vA:13.3","3dmhA-3v8vA:22.41"],["3DOU_A_SAMA1_1","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ASP A 568;ASP A 597;ASP A 615","SAM A 802 (-2.9A);SAM A 802 (-3.5A);None","0.78A","3douA-3v8vA:11.1","3douA-3v8vA:14.84"],["3MEG_A_T27A561_1","P66 REVERSE TRANSCRIPTASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PRO A 310;LEU A 329;VAL A 379;VAL A 306;TYR A 377","None","1.40A","3megA-3v8vA:undetectable","3megA-3v8vA:22.95"],["3TM4_A_SAMA401_0","TRNA (GUANINE N2-)-METHYLTRANSFERASE TRM14","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"MET A 197;GLY A 199;ASN A 309;PRO A 311;LEU A 325","SAM A 801 (-4.5A);SAM A 801 (-3.2A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A);SAM A 801 ( 4.8A)","0.50A","3tm4A-3v8vA:31.0","3tm4A-3v8vA:18.72"],["3TM4_B_SAMB401_0","TRNA (GUANINE N2-)-METHYLTRANSFERASE TRM14","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"MET A 197;GLY A 199;ASN A 309;PRO A 311;LEU A 325","SAM A 801 (-4.5A);SAM A 801 (-3.2A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A);SAM A 801 ( 4.8A)","0.52A","3tm4B-3v8vA:31.2","3tm4B-3v8vA:18.72"],["3UT5_B_LOCB502_1","TUBULIN BETA CHAIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  43;LEU A  20;THR A   8;ALA A   6;ILE A  57","None","1.15A","3ut5B-3v8vA:3.7","3ut5B-3v8vA:20.51"],["3UUD_B_ESTB600_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.36A","3uudB-3v8vA:undetectable","3uudB-3v8vA:16.62"],["3V8V_A_SAMA801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",12,"PRO A 172;ILE A 173;MET A 197;GLY A 199;SER A 200;THR A 202;SER A 263;ASP A 264;VAL A 291;ASN A 309;PRO A 311;LEU A 325","SAM A 801 ( 4.7A);SAM A 801 ( 4.9A);SAM A 801 (-4.5A);SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-4.1A);SAM A 801 (-3.5A);None;SAM A 801 (-3.8A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A);SAM A 801 ( 4.8A)","0.00A","3v8vA-3v8vA:62.9","3v8vA-3v8vA:100.00"],["3V8V_A_SAMA801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",8,"PRO A 172;ILE A 173;SER A 200;THR A 202;ASP A 264;ASN A 309;PRO A 311;LEU A 322","SAM A 801 ( 4.7A);SAM A 801 ( 4.9A);SAM A 801 (-3.0A);SAM A 801 (-4.1A);None;SAM A 801 (-4.5A);SAM A 801 ( 4.1A);None","1.46A","3v8vA-3v8vA:62.9","3v8vA-3v8vA:100.00"],["3V8V_A_SAMA802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A 546;TYR A 548;ASP A 568;CYH A 598;PRO A 616","SAM A 802 (-4.5A);SAM A 802 (-4.7A);SAM A 802 (-2.9A);SAM A 802 (-3.3A);None","1.39A","3v8vA-3v8vA:62.9","3v8vA-3v8vA:100.00"],["3V8V_A_SAMA802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",9,"PHE A 546;TYR A 548;ASP A 568;MET A 569;SER A 570;TYR A 573;ASP A 597;CYH A 598;PRO A 617","SAM A 802 (-4.5A);SAM A 802 (-4.7A);SAM A 802 (-2.9A);SAM A 802 (-3.2A);None;SAM A 802 (-4.6A);SAM A 802 (-3.5A);SAM A 802 (-3.3A);SAM A 802 ( 4.6A)","0.01A","3v8vA-3v8vA:62.9","3v8vA-3v8vA:100.00"],["3V8V_B_SAMB801_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",11,"MET A 197;GLY A 199;ASP A 262;SER A 263;ASP A 264;ASP A 290;VAL A 291;ASN A 309;PRO A 311;TYR A 312;LEU A 325","SAM A 801 (-4.5A);SAM A 801 (-3.2A);SAM A 801 (-2.9A);SAM A 801 (-3.5A);None;SAM A 801 (-3.0A);SAM A 801 (-3.8A);SAM A 801 (-4.5A);SAM A 801 ( 4.1A);None;SAM A 801 ( 4.8A)","0.34A","3v8vB-3v8vA:51.5","3v8vB-3v8vA:100.00"],["3V8V_B_SAMB802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",6,"ARG A 530;PHE A 546;SER A 551;ASP A 597;CYH A 598;PRO A 616","None;SAM A 802 (-4.5A);None;SAM A 802 (-3.5A);SAM A 802 (-3.3A);None","1.43A","3v8vB-3v8vA:51.5","3v8vB-3v8vA:100.00"],["3V8V_B_SAMB802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",11,"ARG A 530;PHE A 546;TYR A 548;SER A 551;MET A 569;SER A 570;TYR A 573;ASP A 597;CYH A 598;ASP A 615;PRO A 617","None;SAM A 802 (-4.5A);SAM A 802 (-4.7A);None;SAM A 802 (-3.2A);None;SAM A 802 (-4.6A);SAM A 802 (-3.5A);SAM A 802 (-3.3A);None;SAM A 802 ( 4.6A)","0.30A","3v8vB-3v8vA:51.5","3v8vB-3v8vA:100.00"],["3V8V_B_SAMB802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PHE A 546;TYR A 548;ASP A 597;CYH A 598;PRO A 617","SAM A 802 (-4.5A);SAM A 802 (-4.7A);SAM A 802 (-3.5A);SAM A 802 (-3.3A);SAM A 802 ( 4.6A)","1.10A","3v8vB-3v8vA:51.5","3v8vB-3v8vA:100.00"],["4DMG_A_SAMA401_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ARG A 530;TYR A 548;ASP A 568;ASP A 615;PRO A 617","None;SAM A 802 (-4.7A);SAM A 802 (-2.9A);None;SAM A 802 ( 4.6A)","0.58A","4dmgA-3v8vA:24.2","4dmgA-3v8vA:21.43"],["4DMG_B_SAMB401_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ARG A 530;TYR A 548;ASP A 568;ASP A 615;PRO A 617","None;SAM A 802 (-4.7A);SAM A 802 (-2.9A);None;SAM A 802 ( 4.6A)","0.58A","4dmgB-3v8vA:24.5","4dmgB-3v8vA:21.43"],["4GKH_J_KANJ301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"ASP A 433;ASP A 422;ASN A 690;ASP A 686","None","1.26A","4gkhJ-3v8vA:undetectable","4gkhJ-3v8vA:18.46"],["4J7X_J_SASJ804_1","SEPIAPTERIN REDUCTASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A 543;LEU A 599;CYH A 598;PHE A 546;ASP A 615","None;None;SAM A 802 (-3.3A);SAM A 802 (-4.5A);None","1.31A","4j7xJ-3v8vA:6.7","4j7xJ-3v8vA:19.01"],["4JUO_F_LFXF101_1","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B;E-SITE DNA","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"SER A 226;GLY A 217;GLU A 175","None","0.53A","4juoA-3v8vA:undetectable;4juoC-3v8vA:undetectable","4juoA-3v8vA:22.98;4juoC-3v8vA:22.00"],["4OBW_D_SAMD601_1","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ASN A 690;ASP A 525;ASP A 519","None","0.88A","4obwD-3v8vA:12.8","4obwD-3v8vA:15.16"],["4X1I_D_LOCD502_1","TUBULIN BETA CHAIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  43;LEU A  20;THR A   8;ALA A   6;ILE A  57","None","1.13A","4x1iD-3v8vA:3.4","4x1iD-3v8vA:20.51"],["4X20_D_LOCD502_2","TUBULIN BETA CHAIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  43;LEU A  20;THR A   8;ALA A   6;ILE A  57","None","1.17A","4x20D-3v8vA:3.5","4x20D-3v8vA:20.51"],["4XMF_A_HSMA202_1","NITROPHORIN-7","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",3,"ASP A 153;LEU A 159;GLY A 158","None","0.44A","4xmfA-3v8vA:undetectable","4xmfA-3v8vA:13.22"],["5E72_A_SAMA400_1","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"ASP A 195;GLY A 199;ASP A 262;ASP A 290","None;SAM A 801 (-3.2A);SAM A 801 (-2.9A);SAM A 801 (-3.0A)","0.47A","5e72A-3v8vA:17.8","5e72A-3v8vA:19.55"],["5HFJ_A_SAMA301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 290;PRO A 311;GLY A 199;THR A 202;SER A 263","SAM A 801 (-3.0A);SAM A 801 ( 4.1A);SAM A 801 (-3.2A);SAM A 801 (-4.1A);SAM A 801 (-3.5A)","0.73A","5hfjA-3v8vA:2.6","5hfjA-3v8vA:14.74"],["5HFJ_B_SAMB301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"PRO A 311;GLY A 199;SER A 200;THR A 202;SER A 263","SAM A 801 ( 4.1A);SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-4.1A);SAM A 801 (-3.5A)","0.64A","5hfjB-3v8vA:2.7","5hfjB-3v8vA:14.74"],["5HFJ_C_SAMC301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 290;PRO A 311;GLY A 199;THR A 202;SER A 263","SAM A 801 (-3.0A);SAM A 801 ( 4.1A);SAM A 801 (-3.2A);SAM A 801 (-4.1A);SAM A 801 (-3.5A)","0.69A","5hfjC-3v8vA:3.8","5hfjC-3v8vA:14.74"],["5HFJ_D_SAMD301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",6,"ASP A 290;PRO A 311;GLY A 199;SER A 200;THR A 202;SER A 263","SAM A 801 (-3.0A);SAM A 801 ( 4.1A);SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-4.1A);SAM A 801 (-3.5A)","0.62A","5hfjD-3v8vA:3.6","5hfjD-3v8vA:14.74"],["5HFJ_E_SAME301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 290;GLY A 199;SER A 200;THR A 202;SER A 263","SAM A 801 (-3.0A);SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-4.1A);SAM A 801 (-3.5A)","0.61A","5hfjE-3v8vA:3.5","5hfjE-3v8vA:14.74"],["5HFJ_F_SAMF301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 290;PRO A 311;GLY A 199;SER A 200;SER A 263","SAM A 801 (-3.0A);SAM A 801 ( 4.1A);SAM A 801 (-3.2A);SAM A 801 (-3.0A);SAM A 801 (-3.5A)","0.80A","5hfjF-3v8vA:4.0","5hfjF-3v8vA:14.74"],["5HFJ_H_SAMH301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ASP A 597;ASP A 615;PRO A 617;PHE A 546;TYR A 573","SAM A 802 (-3.5A);None;SAM A 802 ( 4.6A);SAM A 802 (-4.5A);SAM A 802 (-4.6A)","0.94A","5hfjH-3v8vA:4.7","5hfjH-3v8vA:14.74"],["5HYR_A_ESTA601_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.37A","5hyrA-3v8vA:undetectable","5hyrA-3v8vA:16.90"],["5MIO_B_LOCB502_1","TUBULIN BETA CHAIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"LEU A  43;LEU A  20;THR A   8;ALA A   6;ILE A  57","None","1.09A","5mioB-3v8vA:3.5","5mioB-3v8vA:20.22"],["5UUN_A_ACTA309_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"LEU A  16;GLY A  34;SER A   7;SER A  55","None","1.29A","5uunA-3v8vA:undetectable","5uunA-3v8vA:19.19"],["5UUN_B_ACTB306_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"LEU A  16;GLY A  34;SER A   7;SER A  55","None","1.30A","5uunB-3v8vA:undetectable","5uunB-3v8vA:19.19"],["5WGD_A_ESTA601_1","ESTROGEN RECEPTOR","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",5,"ALA A   6;LEU A  16;LEU A  12;HIS A 160;LEU A 159","None","1.34A","5wgdA-3v8vA:undetectable","5wgdA-3v8vA:8.07"],["6APH_A_ADNA501_2","ADENOSYLHOMOCYSTEINASE","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"THR A 651;THR A 682;HIS A 526;LEU A 533","None","1.44A","6aphA-3v8vA:5.0","6aphA-3v8vA:21.60"],["6DCH_A_ACTA401_0","SCOE PROTEIN","3v8v","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","Escherichia coli",4,"THR A 679;HIS A 526;ASP A 615;HIS A 694","None","1.43A","6dchA-3v8vA:undetectable","6dchA-3v8vA:18.04"]]