SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  75
GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.34A 1dx6A-3v9aA:
16.3		 1dx6A-3v9aA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		6 / 12 ALA A 152
GLY A 146
GLY A 148
LEU A 102
LEU A 104
LEU A 138
 None
 1.12A 1eizA-3v9aA:
3.4		 1eizA-3v9aA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		6 / 12 ALA A 152
GLY A 146
GLY A 148
LEU A 102
LEU A 104
LEU A 138
 None
 1.10A 1ej0A-3v9aA:
2.6		 1ej0A-3v9aA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 ILE A 199
HIS A  74
LEU A 149
LEU A 108
TYR A 106
 None
None
None
SO4  A 401 (-4.0A)
None
 1.31A 1fm6X-3v9aA:
undetectable		 1fm6X-3v9aA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  75
GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.35A 1qtiA-3v9aA:
15.9		 1qtiA-3v9aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		3 / 3 ALA A  55
VAL A  51
TRP A  58
 None
 0.86A 1tkqA-3v9aA:
undetectable		 1tkqA-3v9aA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  75
GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.32A 1w6rA-3v9aA:
5.8		 1w6rA-3v9aA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 9 GLY A  75
GLY A  76
SER A 144
ALA A 145
HIS A 268
 None
 0.86A 2aceA-3v9aA:
4.4		 2aceA-3v9aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 9 GLY A  76
GLY A  77
SER A 144
ALA A 145
HIS A 268
 None
 0.50A 2aceA-3v9aA:
4.4		 2aceA-3v9aA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 11 ALA A 251
LEU A 154
SER A 258
LEU A 230
LEU A 151
 None
 1.04A 2ceoA-3v9aA:
0.1		 2ceoA-3v9aA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 8 GLY A  76
GLY A  77
ALA A 145
HIS A 268
 None
 0.30A 2ha4A-3v9aA:
6.8		 2ha4A-3v9aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 7 GLY A  75
GLY A  76
ALA A 145
HIS A 268
 None
 0.67A 2ha4B-3v9aA:
16.5		 2ha4B-3v9aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 7 GLY A  76
GLY A  77
ALA A 145
HIS A 268
 None
 0.30A 2ha4B-3v9aA:
16.5		 2ha4B-3v9aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 10 ALA A 251
LEU A 154
SER A 258
LEU A 230
LEU A 151
 None
 1.11A 2xn7A-3v9aA:
undetectable
2xn7B-3v9aA:
undetectable		 2xn7A-3v9aA:
21.89
2xn7B-3v9aA:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 THR A  85
ILE A  83
GLY A  75
GLY A  81
SER A  82
 None
 1.06A 2yvlA-3v9aA:
3.0		 2yvlA-3v9aA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  76
ILE A 199
ASN A 200
ALA A 203
LEU A 149
 None
 1.07A 3ckkA-3v9aA:
undetectable		 3ckkA-3v9aA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 7 GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.42A 3o9mA-3v9aA:
16.8		 3o9mA-3v9aA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 6 GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.49A 3o9mB-3v9aA:
16.8		 3o9mB-3v9aA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 10 GLY A 148
LEU A 230
LEU A 247
ASP A 243
ILE A 232
 None
 0.92A 3wdmB-3v9aA:
undetectable		 3wdmB-3v9aA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 9 GLY A 148
LEU A 230
LEU A 247
ASP A 243
ILE A 232
 None
 0.88A 3wdmC-3v9aA:
undetectable		 3wdmC-3v9aA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 10 GLY A 148
LEU A 230
LEU A 247
ASP A 243
ILE A 232
 None
 0.91A 3wdmD-3v9aA:
undetectable		 3wdmD-3v9aA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  75
GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.29A 4ey6A-3v9aA:
16.7		 4ey6A-3v9aA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A  75
GLY A  76
GLY A  77
SER A 144
HIS A 268
 None
 0.31A 4ey6B-3v9aA:
16.3		 4ey6B-3v9aA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 5 VAL A 287
ARG A 286
MET A 291
GLU A 293
 None
 1.10A 4hojA-3v9aA:
undetectable		 4hojA-3v9aA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 ASP A 143
ILE A 199
TYR A 106
LEU A 103
HIS A  86
 None
 1.37A 4j03A-3v9aA:
15.0		 4j03A-3v9aA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 12 GLY A 147
ALA A 145
THR A  85
HIS A  86
GLY A  76
 None
 0.86A 4ls7A-3v9aA:
undetectable		 4ls7A-3v9aA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		3 / 3 ALA A 100
TRP A  58
VAL A  59
 None
 0.25A 4w9nC-3v9aA:
2.7		 4w9nC-3v9aA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 5 VAL A 150
HIS A 271
LEU A 247
ASP A 143
 None
 1.42A 5vcvA-3v9aA:
undetectable		 5vcvA-3v9aA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		5 / 9 VAL A 287
GLY A 147
TYR A  72
VAL A 150
ASP A 143
 None
 1.30A 5zncA-3v9aA:
2.8		 5zncA-3v9aA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 4 MET A  80
GLY A  81
HIS A  74
GLY A  76
 None
 1.48A 6fgdA-3v9aA:
3.2		 6fgdA-3v9aA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3v9a ESTERASE/LIPASE
(uncultured
bacterium) 		4 / 5 LEU A 103
ILE A 232
MET A  89
GLY A  91
 None
 1.05A 6hd6A-3v9aA:
undetectable		 6hd6A-3v9aA:
14.85