SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3v9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		4 / 5 ARG A  90
ALA A  89
ASP A  92
GLY A   4
 None
 1.08A 1e7cA-3v9pA:
undetectable		 1e7cA-3v9pA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		4 / 5 LEU A 136
ASP A 138
ALA A 176
ILE A 185
 None
None
None
GOL  A 252 (-3.8A)
 0.97A 2aofB-3v9pA:
undetectable		 2aofB-3v9pA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		5 / 12 GLY A   4
VAL A  40
ASP A 101
PHE A  99
PHE A 129
 None
 1.08A 3qowA-3v9pA:
undetectable		 3qowA-3v9pA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		5 / 12 SER A  96
VAL A  95
GLN A 198
PHE A  24
HIS A  20
 None
None
GOL  A 252 ( 4.5A)
None
None
 1.37A 4c49D-3v9pA:
undetectable		 4c49D-3v9pA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		5 / 12 PHE A  24
GLY A 201
ILE A   7
VAL A 135
VAL A 184
 None
None
None
None
GOL  A 252 ( 3.8A)
 0.98A 4nkxA-3v9pA:
undetectable		 4nkxA-3v9pA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		5 / 12 PHE A  24
GLY A 201
ILE A   7
VAL A 135
VAL A 184
 None
None
None
None
GOL  A 252 ( 3.8A)
 0.96A 4nkxC-3v9pA:
undetectable		 4nkxC-3v9pA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		5 / 12 PHE A  24
GLY A 201
ILE A   7
VAL A 135
VAL A 184
 None
None
None
None
GOL  A 252 ( 3.8A)
 0.97A 4nkxD-3v9pA:
undetectable		 4nkxD-3v9pA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3v9p THYMIDYLATE KINASE
(Burkholderia
thailandensis) 		3 / 3 HIS A  20
LYS A  17
PHE A 137
 None
 1.50A 5klaA-3v9pA:
undetectable		 5klaA-3v9pA:
21.20