SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3va1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3va1 MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 100
ASP A  91
ALA A  76
GLY A  97
LEU A 122
 None
 1.00A 1rjdA-3va1A:
undetectable		 1rjdA-3va1A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3va1 MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 100
ASP A  91
ALA A  76
GLY A  97
LEU A 122
 None
 0.98A 1rjdB-3va1A:
undetectable		 1rjdB-3va1A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3va1 MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 100
ASP A  91
ALA A  76
GLY A  97
LEU A 122
 None
 1.00A 1rjdC-3va1A:
undetectable		 1rjdC-3va1A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3va1 MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1
(Mus
musculus) 		5 / 10 VAL A  64
ILE A  71
THR A  98
ILE A 121
LEU A  34
 None
 1.12A 1z11D-3va1A:
undetectable		 1z11D-3va1A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3va1 MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1
(Mus
musculus) 		4 / 6 LEU A 122
ILE A  71
HIS A  75
PRO A  87
 None
 1.09A 4xi3C-3va1A:
undetectable		 4xi3C-3va1A:
21.85