SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3va9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 11 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.42A 3mbhA-3va9A:
undetectable		 3mbhA-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.42A 3mbhB-3va9A:
undetectable		 3mbhB-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.44A 3mbhC-3va9A:
undetectable		 3mbhC-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.41A 3mbhD-3va9A:
undetectable		 3mbhD-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.41A 3mbhE-3va9A:
undetectable		 3mbhE-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 11 SER A 160
VAL A 163
LEU A 116
HIS A 112
GLN A 109
 None
 1.47A 3mbhF-3va9A:
undetectable		 3mbhF-3va9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 11 ALA A  91
SER A  57
THR A 120
LEU A 161
VAL A  63
 None
 1.44A 4kyaA-3va9A:
undetectable		 4kyaA-3va9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 11 ALA A  91
SER A  57
THR A 120
LEU A 161
VAL A  63
 None
 1.43A 4kyaE-3va9A:
undetectable		 4kyaE-3va9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		5 / 11 ALA A  91
SER A  57
THR A 120
LEU A 161
VAL A  63
 None
 1.43A 4kyaG-3va9A:
undetectable		 4kyaG-3va9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		3 / 4 ARG A  71
GLY A  72
GLU A  70
 None
 0.46A 4z2dB-3va9A:
undetectable
4z2dC-3va9A:
undetectable		 4z2dB-3va9A:
18.24
4z2dC-3va9A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		4 / 7 LEU A  99
ALA A  52
LEU A 103
ALA A 167
 None
 0.62A 4z90F-3va9A:
6.1
4z90G-3va9A:
7.5
4z90H-3va9A:
7.2
4z90J-3va9A:
7.6		 4z90F-3va9A:
19.25
4z90G-3va9A:
19.25
4z90H-3va9A:
19.25
4z90J-3va9A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		4 / 7 LEU A 103
ALA A 167
LEU A  99
ALA A  52
 None
 0.62A 4z90F-3va9A:
6.1
4z90G-3va9A:
7.5
4z90H-3va9A:
7.2
4z90J-3va9A:
7.6		 4z90F-3va9A:
19.25
4z90G-3va9A:
19.25
4z90H-3va9A:
19.25
4z90J-3va9A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3va9 SENSOR HISTIDINE
KINASE
(Rhodopseudomonas
palustris) 		4 / 4 GLY A 134
LEU A  74
VAL A 130
GLU A  70
 None
 1.27A 5yw0A-3va9A:
undetectable		 5yw0A-3va9A:
22.67