SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vas'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 138
PHE A 169
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.29A 1bx4A-3vasA:
49.7		 1bx4A-3vasA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 THR A 265
GLY A 267
VAL A 286
ILE A 294
ALA A 300
GLY A 301
ALA A 329
ILE A 333
 None
 0.62A 1bx4A-3vasA:
49.7		 1bx4A-3vasA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 THR A 265
ILE A 294
GLY A 299
ALA A 329
ILE A 333
 None
None
ADN  A 401 ( 3.8A)
None
None
 0.94A 1bx4A-3vasA:
49.7		 1bx4A-3vasA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 9 ASN A  14
ASP A  18
GLY A  64
ASN A  68
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.51A 1dgmA-3vasA:
41.4		 1dgmA-3vasA:
31.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		10 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASN A 298
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.32A 1liiA-3vasA:
46.4		 1liiA-3vasA:
30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASN A 298
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.34A 1likA-3vasA:
45.8		 1likA-3vasA:
30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 10 THR A 265
GLY A 267
VAL A 286
ALA A 300
ALA A 329
ILE A 333
 None
 0.41A 1likA-3vasA:
45.8		 1likA-3vasA:
30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 5 SER A 197
PHE A 192
VAL A 170
PHE A 169
 None
None
None
ADN  A 401 (-3.7A)
 1.32A 1oipA-3vasA:
undetectable		 1oipA-3vasA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 GLY A 221
ILE A 218
SER A 216
PHE A 169
TYR A 165
 None
None
None
ADN  A 401 (-3.7A)
None
 1.19A 1ri4A-3vasA:
2.6		 1ri4A-3vasA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 5 ALA A 244
TYR A 246
ALA A 226
TYR A 229
 None
 1.14A 1xl6A-3vasA:
undetectable
1xl6B-3vasA:
undetectable		 1xl6A-3vasA:
21.04
1xl6B-3vasA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ILE A  73
GLY A  11
ILE A 166
ALA A 305
ILE A 309
 None
 0.86A 2b60A-3vasA:
undetectable		 2b60A-3vasA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.32A 2c49A-3vasA:
28.9		 2c49A-3vasA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 7 ASP A  18
GLY A  63
GLY A  64
ASN A  68
 ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
 0.47A 2c49B-3vasA:
27.7		 2c49B-3vasA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 7 VAL A 209
SER A 202
LEU A 250
THR A 243
 None
 1.11A 2f78A-3vasA:
undetectable		 2f78A-3vasA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 7 VAL A 209
SER A 202
LEU A 250
THR A 243
 None
 1.17A 2f78B-3vasA:
undetectable		 2f78B-3vasA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		3 / 3 ASN A 172
ILE A 166
MET A 212
 None
 0.84A 2h42C-3vasA:
undetectable		 2h42C-3vasA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.37A 2pkkA-3vasA:
29.1		 2pkkA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 GLY A  63
GLY A  64
ASN A  68
ALA A 167
GLY A 299
ASP A 302
 ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
CL  A 402 ( 4.2A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.81A 2pkkA-3vasA:
29.1		 2pkkA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.35A 2pkmA-3vasA:
28.9		 2pkmA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 GLY A  63
GLY A  64
ASN A  68
ALA A 167
GLY A 299
ASP A 302
 ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
CL  A 402 ( 4.2A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.82A 2pkmA-3vasA:
28.9		 2pkmA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ILE A  73
GLY A  11
ILE A 166
ALA A 305
ILE A 309
 None
 0.88A 2rkfA-3vasA:
undetectable		 2rkfA-3vasA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 4 ALA A 244
TYR A 246
ALA A 226
TYR A 229
 None
 1.11A 2wlkA-3vasA:
undetectable
2wlkB-3vasA:
undetectable		 2wlkA-3vasA:
21.04
2wlkB-3vasA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ILE A  61
GLY A 299
GLY A 337
LEU A 201
PHE A 169
 None
ADN  A 401 ( 3.8A)
None
None
ADN  A 401 (-3.7A)
 1.07A 2y7hB-3vasA:
3.9		 2y7hB-3vasA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ILE A  61
GLY A 299
GLY A 337
LEU A 201
PHE A 169
 None
ADN  A 401 ( 3.8A)
None
None
ADN  A 401 (-3.7A)
 1.07A 2y7hC-3vasA:
4.4		 2y7hC-3vasA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 8 TYR A  97
ASN A 100
LYS A  99
PHE A  81
 None
 1.32A 3bjwD-3vasA:
undetectable		 3bjwD-3vasA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		3 / 3 VAL A 158
VAL A 154
TRP A 155
 None
 0.91A 3l8lA-3vasA:
undetectable
3l8lB-3vasA:
undetectable		 3l8lA-3vasA:
15.49
3l8lB-3vasA:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.44A 3uboA-3vasA:
40.0		 3uboA-3vasA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ASP A  18
ARG A 132
THR A 136
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
None
ADN  A 401 (-3.1A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.98A 3uboA-3vasA:
40.0		 3uboA-3vasA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.50A 3uboB-3vasA:
40.5		 3uboB-3vasA:
25.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
ILE A  38
LEU A  40
GLY A  63
GLY A  64
ASN A  68
VAL A 123
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 (-4.3A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.11A 3uq6A-3vasA:
62.7		 3uq6A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 5 LEU A  16
ALA A  65
MET A 134
PHE A 169
ASN A 298
 ADN  A 401 (-4.7A)
ADN  A 401 (-3.8A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
 0.19A 3uq6A-3vasA:
62.7		 3uq6A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
ILE A  38
LEU A  40
GLY A  64
ALA A  65
ASN A  68
VAL A 123
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 (-4.3A)
None
ADN  A 401 (-3.7A)
ADN  A 401 (-3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.29A 3uq6B-3vasA:
58.8		 3uq6B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 5 LEU A  16
GLY A  63
MET A 134
PHE A 169
ASN A 298
 ADN  A 401 (-4.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
 0.25A 3uq6B-3vasA:
58.8		 3uq6B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 5 LEU A  16
GLY A  64
MET A 134
ASN A 298
 ADN  A 401 (-4.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.7A)
 1.13A 3uq6B-3vasA:
58.8		 3uq6B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
ILE A  38
LEU A  40
GLY A  63
GLY A  64
ASN A  68
VAL A 123
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 (-4.3A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.10A 3vaqA-3vasA:
63.2		 3vaqA-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 4 LEU A  16
ALA A  65
PHE A 169
ASN A 298
 ADN  A 401 (-4.7A)
ADN  A 401 (-3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
 0.12A 3vaqA-3vasA:
63.2		 3vaqA-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
ILE A  38
LEU A  40
GLY A  64
ALA A  65
ASN A  68
VAL A 123
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 (-4.3A)
None
ADN  A 401 (-3.7A)
ADN  A 401 (-3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.26A 3vaqB-3vasA:
58.1		 3vaqB-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 4 LEU A  16
GLY A  63
MET A 134
PHE A 169
 ADN  A 401 (-4.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.7A)
 0.37A 3vaqB-3vasA:
58.1		 3vaqB-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
ALA A  65
ASN A  68
VAL A 123
MET A 134
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.27A 4dc3A-3vasA:
57.8		 4dc3A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASN A  14
LEU A  40
ALA A  65
ASN A  68
GLY A 301
ASP A 302
 ADN  A 401 ( 4.0A)
None
ADN  A 401 (-3.8A)
ADN  A 401 (-3.7A)
None
ADN  A 401 (-2.9A)
 1.38A 4dc3A-3vasA:
57.8		 4dc3A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 GLY A  64
ASN A  68
VAL A 123
MET A 134
THR A 136
GLY A 299
 ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.1A)
ADN  A 401 ( 3.8A)
 1.15A 4dc3A-3vasA:
57.8		 4dc3A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 4 LEU A  16
ILE A  38
GLY A  64
PHE A 169
 ADN  A 401 (-4.7A)
ADN  A 401 (-4.3A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
 0.60A 4dc3A-3vasA:
57.8		 4dc3A-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		12 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
VAL A 123
THR A 136
LEU A 138
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.15A 4dc3B-3vasA:
62.6		 4dc3B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 GLY A  64
VAL A 123
THR A 136
LEU A  40
ASN A 298
GLY A 299
 ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
None
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
 1.24A 4dc3B-3vasA:
62.6		 4dc3B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 LEU A  40
GLY A  63
ASN A  68
VAL A 123
THR A 136
ASN A 298
GLY A 299
 None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
 1.13A 4dc3B-3vasA:
62.6		 4dc3B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 LEU A 138
GLY A  63
VAL A 123
THR A 136
ASN A 298
GLY A 299
 ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-4.5A)
ADN  A 401 (-3.1A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
 1.30A 4dc3B-3vasA:
62.6		 4dc3B-3vasA:
99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 5 LEU A  16
ILE A  38
ALA A  65
MET A 134
PHE A 169
 ADN  A 401 (-4.7A)
ADN  A 401 (-4.3A)
ADN  A 401 (-3.8A)
ADN  A 401 ( 4.0A)
ADN  A 401 (-3.7A)
 0.56A 4dc3B-3vasA:
62.6		 4dc3B-3vasA:
99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4e3aA-3vasA:
40.3		 4e3aA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.44A 4e3aB-3vasA:
40.5		 4e3aB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
ASN A  68
THR A 136
LEU A  40
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 1.34A 4e3aB-3vasA:
40.5		 4e3aB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 GLY A  64
ASN A  68
THR A 136
LEU A  40
GLY A 299
ASP A 302
 ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 1.45A 4e3aB-3vasA:
40.5		 4e3aB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4jksA-3vasA:
40.6		 4jksA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.39A 4jksB-3vasA:
40.5		 4jksB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4jkuA-3vasA:
40.6		 4jkuA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4jkuB-3vasA:
40.5		 4jkuB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_B_IZPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 6 VAL A 158
TYR A 164
TRP A 155
HIS A 184
 None
 1.42A 4jtrB-3vasA:
undetectable		 4jtrB-3vasA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.39A 4k8cA-3vasA:
40.4		 4k8cA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4k8cB-3vasA:
40.6		 4k8cB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.37A 4k8kA-3vasA:
40.5		 4k8kA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.37A 4k8kB-3vasA:
40.5		 4k8kB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.43A 4k8pA-3vasA:
40.6		 4k8pA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4k8pB-3vasA:
40.5		 4k8pB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4k8tA-3vasA:
40.5		 4k8tA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4k8tB-3vasA:
40.5		 4k8tB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4k93A-3vasA:
40.6		 4k93A-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.40A 4k93B-3vasA:
40.5		 4k93B-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.44A 4k9cA-3vasA:
40.6		 4k9cA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.43A 4k9cB-3vasA:
40.6		 4k9cB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4k9iA-3vasA:
40.7		 4k9iA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4k9iB-3vasA:
40.6		 4k9iB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4kadA-3vasA:
40.6		 4kadA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.41A 4kadB-3vasA:
40.6		 4kadB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.37A 4kahA-3vasA:
40.7		 4kahA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.37A 4kahB-3vasA:
40.5		 4kahB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4kalA-3vasA:
40.5		 4kalA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4kalB-3vasA:
40.6		 4kalB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.39A 4kanA-3vasA:
40.5		 4kanA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.39A 4kanB-3vasA:
40.5		 4kanB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.36A 4kbeA-3vasA:
40.7		 4kbeA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.37A 4kbeB-3vasA:
40.6		 4kbeB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.39A 4lbgA-3vasA:
40.5		 4lbgA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4lbgB-3vasA:
40.5		 4lbgB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4lbxA-3vasA:
40.5		 4lbxA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.42A 4lbxB-3vasA:
40.5		 4lbxB-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.43A 4lc4A-3vasA:
40.4		 4lc4A-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
LEU A 138
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-4.9A)
ADN  A 401 (-2.9A)
 0.43A 4lc4B-3vasA:
40.5		 4lc4B-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4lcaA-3vasA:
40.5		 4lcaA-3vasA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
THR A 136
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.1A)
ADN  A 401 (-2.9A)
 0.38A 4lcaB-3vasA:
40.6		 4lcaB-3vasA:
28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  64
ASN A  68
PHE A 169
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.43A 4n09A-3vasA:
47.3		 4n09A-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
LEU A 138
PHE A 169
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 1.39A 4n09A-3vasA:
47.3		 4n09A-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
PHE A 169
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.43A 4n09B-3vasA:
47.2		 4n09B-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASN A  14
LEU A  40
ASN A  68
PHE A 169
GLY A 301
ASP A 302
 ADN  A 401 ( 4.0A)
None
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
None
ADN  A 401 (-2.9A)
 1.23A 4n09B-3vasA:
47.2		 4n09B-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
ASN A  68
LEU A  40
PHE A 169
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 (-3.7A)
None
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 1.44A 4n09C-3vasA:
47.3		 4n09C-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		9 / 12 ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 138
PHE A 169
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.39A 4n09C-3vasA:
47.3		 4n09C-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 LEU A  40
ASN A  68
LEU A 138
PHE A 169
GLY A 301
ASP A 302
 None
ADN  A 401 (-3.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
None
ADN  A 401 (-2.9A)
 1.25A 4n09C-3vasA:
47.3		 4n09C-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		10 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
PHE A 169
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 ( 4.0A)
ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.54A 4n09D-3vasA:
47.4		 4n09D-3vasA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		6 / 12 ASP A  18
LEU A 138
PHE A 169
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 1.46A 4n09D-3vasA:
47.4		 4n09D-3vasA:
30.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 302
 ADN  A 401 (-2.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-2.9A)
 0.27A 4ubeA-3vasA:
29.1		 4ubeA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 GLY A  63
GLY A  64
ASN A  68
ALA A 167
ASP A 302
 ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
CL  A 402 ( 4.2A)
ADN  A 401 (-2.9A)
 0.83A 4ubeA-3vasA:
29.1		 4ubeA-3vasA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 LEU A 107
LEU A 340
LEU A  67
ALA A  62
ILE A  98
 None
 1.07A 4x1yB-3vasA:
6.6		 4x1yB-3vasA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		4 / 7 LEU A 138
LEU A  16
THR A  66
THR A 173
 ADN  A 401 (-4.9A)
ADN  A 401 (-4.7A)
CL  A 402 (-3.8A)
None
 0.79A 4z90A-3vasA:
undetectable
4z90B-3vasA:
undetectable
4z90C-3vasA:
undetectable
4z90D-3vasA:
undetectable
4z90E-3vasA:
undetectable		 4z90A-3vasA:
21.19
4z90B-3vasA:
21.19
4z90C-3vasA:
21.19
4z90D-3vasA:
21.19
4z90E-3vasA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 12 LEU A 186
PHE A 252
LEU A 261
ILE A 309
GLU A 189
 None
 1.34A 5ienA-3vasA:
undetectable		 5ienA-3vasA:
16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		10 / 12 ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 138
PHE A 169
ASN A 298
GLY A 299
ASP A 302
 ADN  A 401 (-2.7A)
None
ADN  A 401 ( 3.8A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 (-4.9A)
ADN  A 401 (-3.7A)
ADN  A 401 (-3.7A)
ADN  A 401 ( 3.8A)
ADN  A 401 (-2.9A)
 0.33A 5kb5A-3vasA:
50.6		 5kb5A-3vasA:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 THR A 265
GLY A 267
ILE A 294
ALA A 300
GLY A 301
ALA A 329
ILE A 333
 None
 0.65A 5kb6A-3vasA:
45.2		 5kb6A-3vasA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 THR A 265
GLY A 267
VAL A 286
ALA A 300
GLY A 301
ALA A 329
ILE A 333
 None
 0.39A 5kb6A-3vasA:
45.2		 5kb6A-3vasA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 THR A 265
GLY A 267
ILE A 294
ALA A 300
GLY A 301
ALA A 329
ILE A 333
 None
 0.61A 5kb6B-3vasA:
45.4		 5kb6B-3vasA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		7 / 12 THR A 265
GLY A 267
VAL A 286
ALA A 300
GLY A 301
ALA A 329
ILE A 333
 None
 0.40A 5kb6B-3vasA:
45.4		 5kb6B-3vasA:
37.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 9 ILE A 263
ASP A 302
GLY A 301
PHE A 304
ALA A 167
 None
ADN  A 401 (-2.9A)
None
None
CL  A 402 ( 4.2A)
 1.33A 5x66C-3vasA:
undetectable		 5x66C-3vasA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 10 ILE A 263
ASP A 302
GLY A 301
PHE A 304
ALA A 167
 None
ADN  A 401 (-2.9A)
None
None
CL  A 402 ( 4.2A)
 1.35A 5x66D-3vasA:
undetectable		 5x66D-3vasA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3vas PUTATIVE ADENOSINE
KINASE
(Schistosoma
mansoni) 		5 / 10 PHE A 308
ILE A 218
GLY A 221
PHE A 220
TYR A 229
 None
 1.48A 5x66D-3vasA:
undetectable		 5x66D-3vasA:
20.83