SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 LEU A 148
PHE A  11
VAL A 207
ALA A  64
HIS A 115
 None
 1.22A 1q23H-3vb0A:
undetectable
1q23I-3vb0A:
undetectable		 1q23H-3vb0A:
21.78
1q23I-3vb0A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 10 GLY A 286
GLY A 239
TYR A 247
GLU A 288
PHE A 224
 None
 1.24A 1w76B-3vb0A:
undetectable		 1w76B-3vb0A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 TRP A  67
LEU A   9
PHE A  11
LEU A 145
LEU A 212
 None
 1.17A 2bxpA-3vb0A:
undetectable		 2bxpA-3vb0A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 5 HIS A 147
HIS A 191
VAL A 149
HIS A 209
 FE2  A 301 (-3.3A)
None
None
FE2  A 301 (-3.4A)
 1.00A 2wkoF-3vb0A:
undetectable		 2wkoF-3vb0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 8 VAL A 149
HIS A 209
PHE A 183
TRP A 176
 None
FE2  A 301 (-3.4A)
None
None
 1.15A 3v35A-3vb0A:
undetectable		 3v35A-3vb0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.71A 4ir0A-3vb0A:
6.3
4ir0B-3vb0A:
6.5		 4ir0A-3vb0A:
19.59
4ir0B-3vb0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.64A 4ir0A-3vb0A:
6.3
4ir0B-3vb0A:
6.5		 4ir0A-3vb0A:
19.59
4ir0B-3vb0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.63A 4jd1A-3vb0A:
6.3
4jd1B-3vb0A:
6.1		 4jd1A-3vb0A:
19.59
4jd1B-3vb0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.76A 4jd1A-3vb0A:
6.3
4jd1B-3vb0A:
6.1		 4jd1A-3vb0A:
19.59
4jd1B-3vb0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.62A 4jh3A-3vb0A:
6.0
4jh3B-3vb0A:
6.1		 4jh3A-3vb0A:
19.93
4jh3B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.60A 4jh3A-3vb0A:
6.0
4jh3B-3vb0A:
6.1		 4jh3A-3vb0A:
19.93
4jh3B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.59A 4jh4A-3vb0A:
6.1
4jh4B-3vb0A:
5.9		 4jh4A-3vb0A:
19.93
4jh4B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.60A 4jh4A-3vb0A:
6.1
4jh4B-3vb0A:
5.9		 4jh4A-3vb0A:
19.93
4jh4B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.61A 4jh5A-3vb0A:
6.0
4jh5B-3vb0A:
5.9		 4jh5A-3vb0A:
19.93
4jh5B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.60A 4jh5A-3vb0A:
6.0
4jh5B-3vb0A:
5.9		 4jh5A-3vb0A:
19.93
4jh5B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 10 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.63A 4jh6A-3vb0A:
6.1
4jh6B-3vb0A:
6.1		 4jh6A-3vb0A:
19.93
4jh6B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 10 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.63A 4jh6A-3vb0A:
6.1
4jh6B-3vb0A:
6.1		 4jh6A-3vb0A:
19.93
4jh6B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 10 HIS A 209
TYR A 250
GLU A 260
HIS A 147
ALA A 194
 FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
FE2  A 301 (-3.3A)
None
 0.61A 4jh8A-3vb0A:
6.1
4jh8B-3vb0A:
4.1		 4jh8A-3vb0A:
19.93
4jh8B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 10 HIS A 147
ALA A 194
HIS A 209
TYR A 250
GLU A 260
 FE2  A 301 (-3.3A)
None
FE2  A 301 (-3.4A)
None
FE2  A 301 (-2.7A)
 0.61A 4jh8A-3vb0A:
6.1
4jh8B-3vb0A:
4.1		 4jh8A-3vb0A:
19.93
4jh8B-3vb0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 ASP A 111
VAL A 193
ALA A 194
PHE A 162
SER A 196
 None
 1.19A 4mmaA-3vb0A:
undetectable		 4mmaA-3vb0A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 6 LEU A  45
GLU A 213
VAL A 220
ALA A 223
 None
 0.89A 4nkxA-3vb0A:
undetectable		 4nkxA-3vb0A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 9 LEU A 132
PHE A 133
ASP A  46
VAL A  32
ILE A  52
 None
 1.21A 4pcuA-3vb0A:
undetectable
4pcuB-3vb0A:
undetectable		 4pcuA-3vb0A:
19.31
4pcuB-3vb0A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 11 GLY A 144
GLY A 136
ILE A 142
GLY A  66
PHE A 123
 None
SO4  A 303 (-3.6A)
None
None
SO4  A 303 (-4.7A)
 1.10A 4qoiA-3vb0A:
undetectable
4qoiB-3vb0A:
undetectable		 4qoiA-3vb0A:
23.08
4qoiB-3vb0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 8 GLU A 178
ASP A 180
ARG A 173
PRO A 282
 None
 1.18A 4uhxA-3vb0A:
undetectable		 4uhxA-3vb0A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 8 GLU A 178
ASP A 180
ARG A 173
PRO A 282
 None
 1.18A 4uhxA-3vb0A:
undetectable		 4uhxA-3vb0A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 7 PHE A 257
ARG A  61
ALA A  63
LEU A  62
 None
 1.12A 4xk8A-3vb0A:
undetectable		 4xk8A-3vb0A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		4 / 4 GLY A  30
VAL A  33
PHE A  11
ILE A  52
 None
 1.17A 4xv2B-3vb0A:
undetectable		 4xv2B-3vb0A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 GLY A 112
TYR A   8
GLY A 146
THR A 192
HIS A 115
 None
 1.22A 6e8qA-3vb0A:
undetectable		 6e8qA-3vb0A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 ASP A 154
LEU A 195
HIS A 115
ASP A 109
ASP A 111
 None
 1.32A 6n91A-3vb0A:
undetectable		 6n91A-3vb0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 ASP A 154
LEU A 195
SER A 160
HIS A 115
ASP A 111
 None
 1.26A 6n91A-3vb0A:
undetectable		 6n91A-3vb0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3vb0 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Sphingomonas
wittichii) 		5 / 12 ASP A 154
LEU A 195
SER A 160
HIS A 115
ASP A 111
 None
 1.25A 6n91B-3vb0A:
undetectable		 6n91B-3vb0A:
12.97