SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_A_STIA3_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A  94
VAL A   9
ILE A  81
MET A 148
 None
 1.17A 1opjA-3vbaA:
undetectable		 1opjA-3vbaA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 12 PHE A  89
SER A  82
LEU A 120
VAL A 114
VAL A 122
 None
 1.33A 1q23B-3vbaA:
undetectable		 1q23B-3vbaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 SER A  82
ILE A  81
ASP A  55
ARG A   8
 None
 0.99A 2v57A-3vbaA:
undetectable		 2v57A-3vbaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 SER A  82
ILE A  81
ASP A  55
ARG A   8
 None
 1.00A 2v57C-3vbaA:
undetectable		 2v57C-3vbaA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 11 LEU A 151
ALA A 153
ILE A 150
LEU A 156
VAL A 100
 None
 1.10A 3gyqB-3vbaA:
undetectable		 3gyqB-3vbaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 12 THR A 134
VAL A  58
GLY A  59
ILE A 105
LEU A 138
 None
 0.85A 3ijdA-3vbaA:
undetectable		 3ijdA-3vbaA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 9 GLY A  60
PHE A  63
GLY A 109
ILE A 105
CYH A  83
 None
 1.31A 3ko0F-3vbaA:
undetectable
3ko0G-3vbaA:
undetectable		 3ko0F-3vbaA:
21.08
3ko0G-3vbaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 10 GLY A  60
PHE A  63
GLY A 109
ILE A 105
CYH A  83
 None
 1.29A 3ko0L-3vbaA:
undetectable
3ko0N-3vbaA:
undetectable		 3ko0L-3vbaA:
21.08
3ko0N-3vbaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		5 / 10 GLY A 109
ILE A 105
CYH A  83
GLY A  60
PHE A  63
 None
 1.26A 3ko0R-3vbaA:
undetectable
3ko0T-3vbaA:
undetectable		 3ko0R-3vbaA:
21.08
3ko0T-3vbaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 7 TYR A  94
VAL A   9
ILE A  81
MET A 148
 None
 1.02A 3mssB-3vbaA:
undetectable		 3mssB-3vbaA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 ASP A  55
ILE A  56
ARG A   8
ASN A 131
 None
 1.16A 6hisA-3vbaA:
undetectable
6hisB-3vbaA:
undetectable		 6hisA-3vbaA:
19.23
6hisB-3vbaA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 ASP A  55
ILE A  56
ARG A   8
ASN A 131
 None
 1.16A 6hisB-3vbaA:
undetectable
6hisC-3vbaA:
undetectable		 6hisB-3vbaA:
19.23
6hisC-3vbaA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 ASP A  55
ILE A  56
ARG A   8
ASN A 131
 None
 1.15A 6hisC-3vbaA:
undetectable
6hisD-3vbaA:
undetectable		 6hisC-3vbaA:
19.23
6hisD-3vbaA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 ASP A  55
ILE A  56
ARG A   8
ASN A 131
 None
 1.16A 6hisD-3vbaA:
undetectable
6hisE-3vbaA:
undetectable		 6hisD-3vbaA:
19.23
6hisE-3vbaA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3vba ISOPROPYLMALATE/CITR
AMALATE ISOMERASE
SMALL SUBUNIT
(Methanocaldococc
us
jannaschii) 		4 / 8 ASN A 131
ASP A  55
ILE A  56
ARG A   8
 None
 1.15A 6hisA-3vbaA:
undetectable
6hisE-3vbaA:
undetectable		 6hisA-3vbaA:
19.23
6hisE-3vbaA:
19.23