SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 ILE A  24
LEU A  50
PHE A  15
TYR A  69
ALA A  67
 None
 1.30A 1hvyB-3vbjA:
undetectable		 1hvyB-3vbjA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		3 / 3 ASP A  79
TYR A  78
GLU A 140
 None
 0.81A 1vm1A-3vbjA:
undetectable		 1vm1A-3vbjA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 11 LEU A  23
ASN A  21
VAL A  18
GLY A  19
LEU A  10
 None
 1.26A 2bxeA-3vbjA:
undetectable		 2bxeA-3vbjA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 GLY A  71
GLY A  70
ALA A  92
ALA A  91
 None
 0.62A 2ha4A-3vbjA:
undetectable		 2ha4A-3vbjA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 7 GLY A  71
GLY A  70
ALA A  92
ALA A  91
 None
 0.65A 2ha4B-3vbjA:
undetectable		 2ha4B-3vbjA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 VAL A  54
THR A  55
VAL A  42
ILE A  44
 None
 0.95A 2qbmA-3vbjA:
undetectable		 2qbmA-3vbjA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 TYR A  90
ILE A 131
ILE A 132
ILE A  83
 None
 0.88A 3p4wC-3vbjA:
undetectable		 3p4wC-3vbjA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 VAL A 118
TYR A  78
VAL A  89
ILE A 138
 None
 1.12A 4aftD-3vbjA:
undetectable
4aftE-3vbjA:
undetectable		 4aftD-3vbjA:
19.75
4aftE-3vbjA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 5 LYS A  26
LEU A  10
GLU A   9
TYR A   5
 None
 1.47A 4z4hA-3vbjA:
undetectable		 4z4hA-3vbjA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 11 VAL A 165
VAL A 150
ILE A 125
ILE A 126
LEU A 154
 None
 1.02A 5e4dB-3vbjA:
undetectable		 5e4dB-3vbjA:
28.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 8 TYR A  69
ILE A  93
TYR A  90
GLY A 103
 None
 0.86A 5esfA-3vbjA:
undetectable		 5esfA-3vbjA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 7 TYR A  90
ILE A 131
ILE A 132
ILE A  83
 None
 0.87A 5murB-3vbjA:
undetectable		 5murB-3vbjA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 TYR A  69
TYR A  90
ILE A 131
ILE A 132
ILE A  83
 None
 1.20A 5mzrA-3vbjA:
undetectable		 5mzrA-3vbjA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 6 MET A  77
ASN A 135
VAL A 137
LEU A 120
 None
 1.35A 5xdhA-3vbjA:
undetectable
5xdhC-3vbjA:
undetectable		 5xdhA-3vbjA:
16.92
5xdhC-3vbjA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 5 MET A  77
ASN A 135
VAL A 137
LEU A 120
 None
 1.24A 5xdhB-3vbjA:
undetectable		 5xdhB-3vbjA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 5 MET A  77
ASN A 135
VAL A 137
LEU A 120
 None
 1.15A 5xdhD-3vbjA:
undetectable		 5xdhD-3vbjA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3vbj GALACTOSIDE
O-ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 4 VAL A 137
GLY A 139
ASP A 156
ASP A 155
 None
 1.31A 6cjkC-3vbjA:
undetectable		 6cjkC-3vbjA:
20.75