SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 7 PHE B 161
PRO B 152
ALA B 165
PHE B 314
 None
 1.19A 1lqtA-3vboB:
undetectable		 1lqtA-3vboB:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 7 PHE B 161
PRO B 152
ALA B 165
PHE B 314
 None
 1.18A 1lquA-3vboB:
undetectable		 1lquA-3vboB:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		5 / 12 LEU B 135
ILE B 177
LEU B 283
PHE B 151
TYR B 171
 None
 1.21A 2qk8A-3vboB:
undetectable		 2qk8A-3vboB:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		5 / 10 PRO B 152
HIS B 278
TYR B 171
GLY B 282
LYS B 150
 None
 1.11A 3pp7B-3vboB:
undetectable		 3pp7B-3vboB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 GLY B 223
TRP B 149
ALA B 224
PHE B 175
 None
 1.25A 3wqwA-3vboB:
undetectable		 3wqwA-3vboB:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		3 / 3 TYR B 217
ASP B 153
ASP B 225
 None
 0.78A 4a6eA-3vboB:
undetectable		 4a6eA-3vboB:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 THR B 137
THR B 298
HIS B 187
LEU B 291
 None
 1.38A 4lvcA-3vboB:
undetectable		 4lvcA-3vboB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 THR B 137
THR B 298
HIS B 187
LEU B 291
 None
 1.38A 4lvcC-3vboB:
undetectable		 4lvcC-3vboB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 LEU B 284
TYR B 199
ALA B 237
ILE B 239
 None
 1.20A 4y03B-3vboB:
undetectable		 4y03B-3vboB:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		3 / 3 SER B 274
ALA B 275
THR B 156
 None
 0.53A 5n0xB-3vboB:
undetectable		 5n0xB-3vboB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 THR B 137
THR B 298
HIS B 187
LEU B 291
 None
 1.40A 6gbnA-3vboB:
undetectable		 6gbnA-3vboB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3vbo GENOME POLYPROTEIN,
CAPSID PROTEIN VP2
(Enterovirus
A) 		4 / 5 THR B 137
THR B 298
HIS B 187
LEU B 291
 None
 1.38A 6gbnD-3vboB:
undetectable		 6gbnD-3vboB:
19.09