SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 7 TYR A  17
ILE A  33
PRO A 115
GLU A 121
 None
 0.39A 1oniA-3vczA:
21.5
1oniB-3vczA:
21.5		 1oniA-3vczA:
37.01
1oniB-3vczA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 6 TYR A  17
ILE A  33
PRO A 115
GLU A 121
 None
 0.37A 1oniB-3vczA:
21.5
1oniC-3vczA:
21.5		 1oniB-3vczA:
37.01
1oniC-3vczA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 6 TYR A  17
ILE A  33
PRO A 115
GLU A 121
 None
 0.35A 1oniA-3vczA:
21.5
1oniC-3vczA:
21.5		 1oniA-3vczA:
37.01
1oniC-3vczA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 7 TYR A  17
ILE A  33
PRO A 115
GLU A 121
 None
 0.39A 1oniD-3vczA:
21.7
1oniE-3vczA:
21.7		 1oniD-3vczA:
37.01
1oniE-3vczA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 7 TYR A  17
ILE A  33
PRO A 115
GLU A 121
 None
 0.39A 1oniG-3vczA:
21.4
1oniI-3vczA:
21.5		 1oniG-3vczA:
37.01
1oniI-3vczA:
37.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		5 / 8 PRO A  43
VAL A  42
PRO A 115
GLN A  32
ILE A 120
 None
 1.37A 4iilA-3vczA:
undetectable		 4iilA-3vczA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3vcz ENDORIBONUCLEASE
L-PSP
(Vibrio
vulnificus) 		4 / 7 LEU A  28
VAL A  61
GLN A  32
GLU A 121
 None
 1.09A 5tudA-3vczA:
undetectable		 5tudA-3vczA:
15.03