SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 6 VAL A   8
VAL A  50
ILE A  60
ASN A 267
 None
 0.98A 1e06A-3vd8A:
undetectable		 1e06A-3vd8A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		3 / 3 GLU A 111
TRP A 230
LYS A 273
 MTT  A1205 (-2.9A)
MTT  A1205 (-4.3A)
None
 1.29A 1qu2A-3vd8A:
undetectable		 1qu2A-3vd8A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 262
ILE A 108
VAL A  97
LEU A  76
ILE A  79
 None
 0.96A 2h42C-3vd8A:
undetectable		 2h42C-3vd8A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 8 THR A  93
LEU A 285
ASP A 287
GLU A 111
 None
None
None
MTT  A1205 (-2.9A)
 1.02A 2zw9A-3vd8A:
undetectable		 2zw9A-3vd8A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLY A1013
ASP A1015
LEU A1081
LEU A1072
ASN A1073
 None
 1.23A 2zw9B-3vd8A:
undetectable		 2zw9B-3vd8A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 192
THR A 193
ALA A 346
THR A 345
ILE A 348
 None
 1.24A 3a35A-3vd8A:
undetectable		 3a35A-3vd8A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 6 PHE A 258
ALA A 162
LEU A 247
PRO A 159
 None
 0.98A 3bgdA-3vd8A:
undetectable		 3bgdA-3vd8A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 7 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.66A 3bjwC-3vd8A:
undetectable		 3bjwC-3vd8A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 8 VAL A 110
GLY A 300
PRO A 229
LYS A 305
 None
 0.86A 3bjwA-3vd8A:
undetectable		 3bjwA-3vd8A:
13.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		12 / 12 ASP A  14
LYS A  15
LYS A  42
GLU A  44
GLU A  45
ALA A  63
ASP A  65
ARG A  66
GLU A 111
PRO A 154
TRP A 230
TYR A 341
 MTT  A1205 (-3.1A)
MTT  A1205 (-2.8A)
MTT  A1205 (-2.7A)
MTT  A1205 (-2.9A)
MTT  A1205 (-3.5A)
MTT  A1205 (-3.3A)
MTT  A1205 ( 2.8A)
MTT  A1205 ( 3.8A)
MTT  A1205 (-2.9A)
MTT  A1205 (-3.5A)
MTT  A1205 (-4.3A)
MTT  A1205 (-4.5A)
 0.40A 3jyrA-3vd8A:
62.6		 3jyrA-3vd8A:
69.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		7 / 7 ASN A  12
TRP A  62
GLU A 153
TYR A 155
MET A 330
TRP A 340
ARG A 344
 MTT  A1205 (-4.6A)
MTT  A1205 (-4.4A)
MTT  A1205 (-3.4A)
MTT  A1205 (-4.0A)
MTT  A1205 ( 4.2A)
MTT  A1205 (-3.9A)
MTT  A1205 (-4.0A)
 0.55A 3jyrA-3vd8A:
62.6		 3jyrA-3vd8A:
69.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 11 GLN A 365
ALA A 364
ALA A 162
GLY A 166
ALA A 188
 None
 1.07A 3mg0V-3vd8A:
undetectable
3mg0W-3vd8A:
undetectable		 3mg0V-3vd8A:
21.99
3mg0W-3vd8A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 VAL A 196
LEU A 160
GLY A 187
ALA A 188
LEU A 361
 None
 1.00A 3n8yB-3vd8A:
undetectable		 3n8yB-3vd8A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MTT  A1205 (-4.9A)
None
None
MTT  A1205 (-2.9A)
None
 0.83A 3tbgB-3vd8A:
undetectable		 3tbgB-3vd8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE A 156
GLY A 300
LEU A 299
GLU A 111
ALA A 231
 MTT  A1205 (-4.9A)
None
None
MTT  A1205 (-2.9A)
None
 0.82A 3tbgD-3vd8A:
undetectable		 3tbgD-3vd8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 231
TYR A  17
TYR A 210
ASN A 234
GLY A 228
 None
 1.34A 3vwqA-3vd8A:
undetectable		 3vwqA-3vd8A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 5 GLU A 308
ASP A 314
ASP A 287
ASN A 294
 EDO  A1204 (-3.6A)
None
None
None
 1.39A 3vywD-3vd8A:
undetectable		 3vywD-3vd8A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ILE A 266
ALA A 105
LEU A  20
VAL A  23
ILE A  59
 None
 1.11A 4m2xG-3vd8A:
undetectable		 4m2xG-3vd8A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
None
None
MTT  A1205 (-3.1A)
 0.96A 4n48A-3vd8A:
undetectable		 4n48A-3vd8A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 9 ALA A 264
ALA A 105
LEU A 103
LEU A 262
VAL A 261
 None
 1.14A 4or0B-3vd8A:
undetectable		 4or0B-3vd8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 11 ILE A 132
LEU A 139
LEU A 122
ALA A 223
LEU A 115
 None
 1.11A 4p65E-3vd8A:
undetectable
4p65F-3vd8A:
undetectable
4p65J-3vd8A:
undetectable
4p65L-3vd8A:
undetectable		 4p65E-3vd8A:
5.06
4p65F-3vd8A:
5.77
4p65J-3vd8A:
5.77
4p65L-3vd8A:
5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 115
ILE A 132
LEU A 139
LEU A 122
ALA A 223
 None
 1.04A 4p65F-3vd8A:
undetectable
4p65H-3vd8A:
undetectable
4p65K-3vd8A:
undetectable
4p65L-3vd8A:
undetectable		 4p65F-3vd8A:
5.77
4p65H-3vd8A:
5.77
4p65K-3vd8A:
5.06
4p65L-3vd8A:
5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLY A  19
GLU A  22
ALA A 292
TYR A 307
SER A 233
 None
 1.28A 4pb1A-3vd8A:
undetectable		 4pb1A-3vd8A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 5 LYS A1026
ARG A1045
LEU A1014
ASN A1044
 None
 1.34A 5osrA-3vd8A:
0.8		 5osrA-3vd8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		4 / 5 LYS A1026
ARG A1045
LEU A1014
ASN A1044
 None
 1.45A 5otrA-3vd8A:
undetectable		 5otrA-3vd8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		6 / 12 ALA A 342
ALA A 338
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.39A 5w4zA-3vd8A:
undetectable		 5w4zA-3vd8A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		6 / 12 ALA A 342
ALA A 338
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.42A 5w4zB-3vd8A:
undetectable		 5w4zB-3vd8A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 338
PRO A 334
GLY A  69
ALA A 342
TYR A1092
 None
K  A1209 ( 4.5A)
K  A1209 (-3.6A)
None
None
 1.21A 5zvgA-3vd8A:
undetectable		 5zvgA-3vd8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 ALA A 338
PRO A 334
GLY A  69
ALA A 342
TYR A1092
 None
K  A1209 ( 4.5A)
K  A1209 (-3.6A)
None
None
 1.19A 5zvgB-3vd8A:
undetectable		 5zvgB-3vd8A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 MTT  A1205 (-4.0A)
None
None
 0.82A 6b58A-3vd8A:
undetectable		 6b58A-3vd8A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU A 275
GLY A  24
VAL A  35
LEU A   7
ILE A   9
 None
 1.01A 6ecxA-3vd8A:
undetectable		 6ecxA-3vd8A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 12 GLN A 365
ALA A 364
ALA A 162
GLY A 166
ALA A 188
 None
 0.97A 6hwdH-3vd8A:
undetectable
6hwdI-3vd8A:
undetectable		 6hwdH-3vd8A:
11.06
6hwdI-3vd8A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2
(Escherichia
coli;
Homo
sapiens) 		5 / 11 GLN A 365
ALA A 364
ALA A 162
GLY A 166
ALA A 188
 None
 0.97A 6hwdV-3vd8A:
undetectable		 6hwdV-3vd8A:
11.06