SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE
(Alcaligenes
faecalis) 		4 / 6 LEU A  60
ILE A  74
VAL A   8
ALA A  77
 None
 0.98A 2j5mA-3vdrA:
undetectable		 2j5mA-3vdrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE
(Alcaligenes
faecalis) 		4 / 5 LEU A  87
ILE A 128
ILE A 137
GLY A 121
 None
 0.89A 3bufA-3vdrA:
undetectable		 3bufA-3vdrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE
(Alcaligenes
faecalis) 		4 / 4 THR A 122
VAL A 162
GLY A 248
THR A 249
 None
 1.01A 3cflA-3vdrA:
undetectable		 3cflA-3vdrA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE
(Alcaligenes
faecalis) 		5 / 12 THR A  10
VAL A 162
GLY A 161
LEU A 113
ILE A  93
 None
None
None
NAI  A 304 ( 4.5A)
None
 1.01A 3ijdA-3vdrA:
2.5		 3ijdA-3vdrA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE
(Alcaligenes
faecalis) 		3 / 3 LYS A   5
ILE A  86
ILE A 138
 None
 0.72A 4y0qA-3vdrA:
undetectable		 4y0qA-3vdrA:
21.53