SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ve2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 PHE A 400
LEU A 382
VAL A 407
GLN A 405
 None
 1.12A 1e7aB-3ve2A:
undetectable		 1e7aB-3ve2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLN A 196
ASP A 191
VAL A 338
GLY A 214
 None
 1.25A 1ekjC-3ve2A:
undetectable
1ekjD-3ve2A:
undetectable		 1ekjC-3ve2A:
16.98
1ekjD-3ve2A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 ASP A 191
VAL A 338
GLY A 214
GLN A 196
 None
 1.23A 1ekjC-3ve2A:
undetectable
1ekjD-3ve2A:
undetectable		 1ekjC-3ve2A:
16.98
1ekjD-3ve2A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLY A 318
GLY A  42
TYR A  41
SER A 316
 None
 0.93A 1eswA-3ve2A:
undetectable		 1eswA-3ve2A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 9 GLY A 328
PRO A  77
GLU A 168
GLY A 167
GLY A 321
 None
 0.81A 1mxdA-3ve2A:
undetectable		 1mxdA-3ve2A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 11 GLY A 328
PRO A  77
GLU A 168
GLY A 167
GLY A 321
 None
 0.80A 1mxgA-3ve2A:
undetectable		 1mxgA-3ve2A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 8 ILE A 163
LEU A  47
LYS A 337
GLY A 209
 None
 1.01A 1os6A-3ve2A:
undetectable		 1os6A-3ve2A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 ILE A 181
ASP A 247
PHE A 248
 GOL  A 706 ( 4.4A)
None
None
 0.56A 1uwjB-3ve2A:
undetectable		 1uwjB-3ve2A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 8 TYR A 104
PHE A 164
HIS A 166
GLY A 167
 None
 0.66A 2ha4A-3ve2A:
undetectable		 2ha4A-3ve2A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 PHE A 682
TYR A 643
GLY A 640
LYS A 639
 None
 1.13A 2i30A-3ve2A:
undetectable		 2i30A-3ve2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLY A 249
PRO A 175
LYS A 377
THR A 379
 None
 1.27A 2m2oB-3ve2A:
undetectable		 2m2oB-3ve2A:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 LEU A 382
LEU A 490
GLY A 651
LEU A 397
VAL A 638
 None
 1.32A 2w8yA-3ve2A:
undetectable		 2w8yA-3ve2A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 GLY A  39
GLY A 317
SER A 316
LEU A 327
PHE A 320
 None
 1.11A 3e23A-3ve2A:
undetectable		 3e23A-3ve2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 HIS A 273
SER A 229
GLU A 228
 None
 0.91A 3s8pA-3ve2A:
undetectable		 3s8pA-3ve2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLY A 239
VAL A 185
HIS A 187
THR A 241
 None
 0.98A 3tj7A-3ve2A:
undetectable
3tj7B-3ve2A:
undetectable		 3tj7A-3ve2A:
16.41
3tj7B-3ve2A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLY A 239
VAL A 185
HIS A 187
THR A 241
 None
 0.98A 3tj7C-3ve2A:
undetectable
3tj7D-3ve2A:
2.2		 3tj7C-3ve2A:
16.41
3tj7D-3ve2A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 VAL A 185
HIS A 187
THR A 241
GLY A 239
 None
 1.00A 3tj7C-3ve2A:
undetectable
3tj7D-3ve2A:
2.2		 3tj7C-3ve2A:
16.41
3tj7D-3ve2A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 ASN A  51
GLU A  58
ARG A  50
 None
None
ACT  A 708 (-3.3A)
 0.93A 3wxoA-3ve2A:
undetectable		 3wxoA-3ve2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 11 ALA A 282
LEU A 315
PHE A 164
LEU A 253
PHE A 319
 None
 0.98A 3zosA-3ve2A:
1.5
3zosB-3ve2A:
1.5		 3zosA-3ve2A:
18.39
3zosB-3ve2A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 HIS A 129
ALA A 344
TYR A 182
GLU A 325
 GOL  A 706 (-4.2A)
None
None
None
 0.99A 4ae1A-3ve2A:
undetectable		 4ae1A-3ve2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 8 SER A 677
ASN A 554
GLY A 617
THR A 613
 None
 0.83A 4fo4B-3ve2A:
undetectable		 4fo4B-3ve2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 ASP A 383
LEU A 382
PRO A 170
ASN A 287
LEU A 174
 None
 1.17A 4gh8A-3ve2A:
undetectable		 4gh8A-3ve2A:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 8 SER A 137
SER A 343
TYR A 104
GLU A 326
 None
 1.16A 4ms4A-3ve2A:
undetectable		 4ms4A-3ve2A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 ASP A 398
PHE A 400
PHE A  43
PHE A 320
GLY A 318
 None
 1.24A 4pevC-3ve2A:
undetectable		 4pevC-3ve2A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 ASP A 579
PRO A 537
THR A 531
GLY A 604
THR A 379
 None
 1.38A 5hfjH-3ve2A:
undetectable		 5hfjH-3ve2A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 11 GLU A 386
SER A 523
GLU A 521
VAL A 407
TYR A 478
 None
 1.21A 5iqdA-3ve2A:
0.0		 5iqdA-3ve2A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 HIS A 235
ASP A 234
HIS A 273
 None
 0.88A 5n1tW-3ve2A:
undetectable		 5n1tW-3ve2A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ve2 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 5 THR A 475
GLU A 521
THR A 388
LEU A 397
 None
 1.27A 5utuH-3ve2A:
undetectable		 5utuH-3ve2A:
21.60