SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ve5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 3ve5 RECOMBINATION
PROTEIN RECR
(Caldanaerobacter
subterraneus) 		3 / 3 CYH D  58
ARG D 128
CYH D  70
 ZN  D 201 (-2.4A)
None
ZN  D 201 (-2.5A)
 1.33A 1p9gA-3ve5D:
undetectable		 1p9gA-3ve5D:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ve5 RECOMBINATION
PROTEIN RECR
(Caldanaerobacter
subterraneus) 		4 / 8 ASP D  68
TYR D  98
TYR D 102
CYH D  70
 None
None
None
ZN  D 201 (-2.5A)
 1.37A 2xz5A-3ve5D:
undetectable
2xz5C-3ve5D:
undetectable		 2xz5A-3ve5D:
22.65
2xz5C-3ve5D:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3ve5 RECOMBINATION
PROTEIN RECR
(Caldanaerobacter
subterraneus) 		3 / 3 HIS D 103
ARG D 128
GLU D 124
 None
 1.06A 3qf1A-3ve5D:
undetectable		 3qf1A-3ve5D:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3ve5 RECOMBINATION
PROTEIN RECR
(Caldanaerobacter
subterraneus) 		5 / 12 VAL D 134
ILE D 109
ILE D 122
LEU D 126
VAL D 129
 None
 1.05A 3w68C-3ve5D:
undetectable		 3w68C-3ve5D:
23.08