SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ve9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		4 / 8 TYR A 184
LYS A 192
GLY A 180
THR A 161
 None
 1.07A 1ykiC-3ve9A:
undetectable
1ykiD-3ve9A:
undetectable		 1ykiC-3ve9A:
22.54
1ykiD-3ve9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		3 / 3 GLY A 180
TYR A 184
SER A   7
 None
None
GOL  A 301 ( 4.6A)
 0.62A 2xatA-3ve9A:
0.6		 2xatA-3ve9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		5 / 12 ILE A  81
ALA A  93
ARG A 126
VAL A 104
HIS A  83
 GOL  A 301 ( 4.7A)
None
None
None
None
 1.00A 2yqzA-3ve9A:
undetectable		 2yqzA-3ve9A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		5 / 9 LEU A  45
LEU A  33
ILE A   5
ILE A  52
VAL A  49
 None
 1.19A 3tmzA-3ve9A:
undetectable		 3tmzA-3ve9A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		3 / 3 LYS A   1
TYR A 176
ARG A   3
 None
 1.32A 4gc9A-3ve9A:
undetectable		 4gc9A-3ve9A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		5 / 12 LEU A 170
GLY A 167
GLN A 200
VAL A 179
THR A 137
 None
 1.39A 4olmA-3ve9A:
undetectable		 4olmA-3ve9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		5 / 8 VAL A  99
ASP A 100
PRO A 129
GLY A 131
LEU A 103
 None
 1.47A 5w3jB-3ve9A:
undetectable		 5w3jB-3ve9A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE
(Metallosphaera
sedula) 		5 / 12 ILE A 155
PHE A 102
LEU A 103
PHE A 132
ASP A 175
 None
 1.35A 6dwnB-3ve9A:
undetectable		 6dwnB-3ve9A:
16.36