SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vea'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_A_DVAA6_0 (GRAMICIDIN A)	3vea	MACRODOMAIN TER PROTEIN (Yersinia pestis)	3 / 3	ALA B 49 VAL B 54 TRP B 70	None	0.85A	1nt5A-3veaB: undetectable	1nt5A-3veaB: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_B_DVAB6_0 (GRAMICIDIN A)	3vea	MACRODOMAIN TER PROTEIN (Yersinia pestis)	3 / 3	ALA B 49 VAL B 54 TRP B 70	None	0.85A	1nt5B-3veaB: undetectable	1nt5B-3veaB: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8Y_C_VK3C202_1 (NADPH QUINONE OXIDOREDUCTASE)	3vea	MACRODOMAIN TER PROTEIN (Yersinia pestis)	4 / 7	ARG B 82 TYR B 30 LEU B 31 ASN B 76	None	1.28A	4f8yC-3veaB: undetectable 4f8yD-3veaB: undetectable	4f8yC-3veaB: 21.05 4f8yD-3veaB: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6J_D_ACTD404_0 (L-LYSINE 3-HYDROXYLASE)	3vea	MACRODOMAIN TER PROTEIN (Yersinia pestis)	4 / 6	GLU B 69 TRP B 70 HIS B 74 ALA B 73	None	1.17A	6f6jC-3veaB: undetectable 6f6jD-3veaB: undetectable	6f6jC-3veaB: 18.18 6f6jD-3veaB: 18.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT5_A_DVAA6_0","GRAMICIDIN A","3vea","MACRODOMAIN TER PROTEIN","Yersinia pestis",3,"ALA B  49;VAL B  54;TRP B  70","None","0.85A","1nt5A-3veaB:undetectable","1nt5A-3veaB:12.86"],["1NT5_B_DVAB6_0","GRAMICIDIN A","3vea","MACRODOMAIN TER PROTEIN","Yersinia pestis",3,"ALA B  49;VAL B  54;TRP B  70","None","0.85A","1nt5B-3veaB:undetectable","1nt5B-3veaB:12.86"],["4F8Y_C_VK3C202_1","NADPH QUINONE OXIDOREDUCTASE;NADPH QUINONE OXIDOREDUCTASE","3vea","MACRODOMAIN TER PROTEIN","Yersinia pestis",4,"ARG B  82;TYR B  30;LEU B  31;ASN B  76","None","1.28A","4f8yC-3veaB:undetectable;4f8yD-3veaB:undetectable","4f8yC-3veaB:21.05;4f8yD-3veaB:21.05"],["6F6J_D_ACTD404_0","L-LYSINE 3-HYDROXYLASE","3vea","MACRODOMAIN TER PROTEIN","Yersinia pestis",4,"GLU B  69;TRP B  70;HIS B  74;ALA B  73","None","1.17A","6f6jC-3veaB:undetectable;6f6jD-3veaB:undetectable","6f6jC-3veaB:18.18;6f6jD-3veaB:18.18"]]