SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ved'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3ved DYPB
(Rhodococcus
jostii) 		3 / 3 THR A 228
GLU A 239
ASP A 162
 None
 0.83A 1nt2A-3vedA:
undetectable		 1nt2A-3vedA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3ved DYPB
(Rhodococcus
jostii) 		5 / 11 LEU A  49
LEU A 119
THR A  15
PRO A  16
LEU A 310
 None
 1.17A 2ft9A-3vedA:
undetectable		 2ft9A-3vedA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3ved DYPB
(Rhodococcus
jostii) 		4 / 8 LEU A 216
GLN A 221
SER A 225
HIS A 226
 None
None
None
HEM  A 401 (-3.2A)
 1.07A 3kp2A-3vedA:
undetectable
3kp2B-3vedA:
undetectable		 3kp2A-3vedA:
18.53
3kp2B-3vedA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3ved DYPB
(Rhodococcus
jostii) 		5 / 12 LEU A 313
VAL A  67
PHE A 302
LEU A 127
TYR A 260
 None
 1.21A 3sp9B-3vedA:
undetectable		 3sp9B-3vedA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ved DYPB
(Rhodococcus
jostii) 		5 / 12 ASP A 288
LEU A 149
HIS A 226
MET A 278
PHE A 279
 None
HEM  A 401 ( 4.7A)
HEM  A 401 (-3.2A)
HEM  A 401 (-3.5A)
None
 1.50A 4pgfA-3vedA:
undetectable		 4pgfA-3vedA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3ved DYPB
(Rhodococcus
jostii) 		4 / 6 ALA A 131
ARG A 121
GLY A 120
GLU A 118
 None
 0.98A 5btgA-3vedA:
1.2
5btgB-3vedA:
undetectable
5btgC-3vedA:
undetectable		 5btgA-3vedA:
21.97
5btgB-3vedA:
25.22
5btgC-3vedA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 3ved DYPB
(Rhodococcus
jostii) 		5 / 12 ASP A 217
ASP A 219
GLU A 203
GLU A 212
GLU A 200
 None
 1.42A 5iqeC-3vedA:
undetectable		 5iqeC-3vedA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3ved DYPB
(Rhodococcus
jostii) 		4 / 7 GLY A 154
ASP A 147
HIS A 226
ASN A 246
 HEM  A 401 (-3.1A)
HEM  A 401 (-4.3A)
HEM  A 401 (-3.2A)
CL  A 404 (-3.2A)
 0.93A 5nnwD-3vedA:
undetectable		 5nnwD-3vedA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3ved DYPB
(Rhodococcus
jostii) 		4 / 7 GLY A 154
ASP A 147
HIS A 226
ASN A 246
 HEM  A 401 (-3.1A)
HEM  A 401 (-4.3A)
HEM  A 401 (-3.2A)
CL  A 404 (-3.2A)
 0.93A 5no9D-3vedA:
undetectable		 5no9D-3vedA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3ved DYPB
(Rhodococcus
jostii) 		4 / 5 VAL A  64
LEU A 119
CYH A 116
ASP A 245
 None
 1.39A 5vcvA-3vedA:
undetectable		 5vcvA-3vedA:
22.83