SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 9 VAL A 162
VAL A 174
LEU A 170
ILE A 409
ALA A 385
 None
 1.06A 1eqgA-3vf1A:
0.0		 1eqgA-3vf1A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 11 VAL A 162
VAL A 174
LEU A 170
ILE A 409
ALA A 385
 None
 1.06A 1eqgB-3vf1A:
undetectable		 1eqgB-3vf1A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 TRP A 148
THR A 384
GLY A 160
TYR A 520
 None
 1.15A 1gtiC-3vf1A:
undetectable		 1gtiC-3vf1A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 8 PHE A 176
GLU A 179
PRO A 167
LEU A 415
 None
 0.65A 1hmyA-3vf1A:
undetectable		 1hmyA-3vf1A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 8 ALA A 193
LEU A 197
ALA A 220
THR A 218
 None
 0.88A 1ie4B-3vf1A:
undetectable
1ie4D-3vf1A:
undetectable		 1ie4B-3vf1A:
12.01
1ie4D-3vf1A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.70A 1rjoA-3vf1A:
undetectable		 1rjoA-3vf1A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.66A 1rkyA-3vf1A:
undetectable		 1rkyA-3vf1A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 4 SER A  22
ILE A  23
VAL A 114
THR A 130
 None
 1.09A 1u70A-3vf1A:
undetectable		 1u70A-3vf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.71A 1w2zB-3vf1A:
undetectable		 1w2zB-3vf1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.72A 1w2zC-3vf1A:
undetectable		 1w2zC-3vf1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.69A 1w2zD-3vf1A:
undetectable		 1w2zD-3vf1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASP A 459
LEU A 460
ILE A 251
SER A 240
PHE A 471
 None
 1.32A 1xmuA-3vf1A:
undetectable		 1xmuA-3vf1A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASP A 459
LEU A 460
ILE A 251
SER A 240
PHE A 471
 None
 1.37A 1xomA-3vf1A:
undetectable		 1xomA-3vf1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASP A 459
LEU A 460
ILE A 251
SER A 240
PHE A 471
 None
 1.37A 1xoqA-3vf1A:
undetectable		 1xoqA-3vf1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASP A 459
LEU A 460
ILE A 251
SER A 240
PHE A 471
 None
 1.37A 1xoqB-3vf1A:
undetectable		 1xoqB-3vf1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 HIS A 368
ILE A 371
VAL A 465
PRO A 248
SER A 573
 None
 1.10A 1zq9A-3vf1A:
undetectable		 1zq9A-3vf1A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 GLU A 249
ASP A 364
PHE A 242
ARG A 361
 None
 1.16A 2a3bB-3vf1A:
undetectable		 2a3bB-3vf1A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 THR A 566
GLY A 245
SER A 246
ASP A 324
ILE A 325
 None
 1.18A 2b25B-3vf1A:
undetectable		 2b25B-3vf1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 556
HIS A 378
HIS A 373
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
 0.74A 2eimN-3vf1A:
undetectable		 2eimN-3vf1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 7 ASN A  44
ASP A  45
THR A   9
GLY A  49
 None
 0.91A 2f6dA-3vf1A:
undetectable		 2f6dA-3vf1A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.71A 2oqeA-3vf1A:
undetectable		 2oqeA-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.71A 2oqeB-3vf1A:
undetectable		 2oqeB-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.71A 2oqeC-3vf1A:
undetectable		 2oqeC-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.70A 2oqeD-3vf1A:
undetectable		 2oqeD-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_E_CUE801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 4 LEU A 613
HIS A 378
HIS A 373
HIS A 556
 None
FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 1.49A 2oqeE-3vf1A:
undetectable		 2oqeE-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.72A 2oqeF-3vf1A:
undetectable		 2oqeF-3vf1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 5 VAL A 604
THR A 605
VAL A 187
GLY A 188
 None
 1.10A 2p2fA-3vf1A:
undetectable		 2p2fA-3vf1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 4 VAL A 604
THR A 605
VAL A 187
GLY A 188
 None
 1.08A 2p2fB-3vf1A:
undetectable		 2p2fB-3vf1A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 PRO A 664
ASN A 658
ARG A 657
 None
 0.93A 2qeuB-3vf1A:
undetectable		 2qeuB-3vf1A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.68A 2w0qA-3vf1A:
undetectable		 2w0qA-3vf1A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.70A 2w0qB-3vf1A:
undetectable		 2w0qB-3vf1A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 556
HIS A 378
HIS A 373
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
 0.70A 3ag4A-3vf1A:
undetectable		 3ag4A-3vf1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 556
HIS A 378
HIS A 373
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
 0.74A 3ag4N-3vf1A:
undetectable		 3ag4N-3vf1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 LEU A 402
VAL A 398
LEU A 515
ASP A 510
 None
 0.90A 3cs9D-3vf1A:
undetectable		 3cs9D-3vf1A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 ILE A 433
LYS A 444
ILE A 371
HIS A 368
 None
 1.20A 3eteA-3vf1A:
undetectable
3eteE-3vf1A:
undetectable		 3eteA-3vf1A:
22.41
3eteE-3vf1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 GLY A 437
GLY A 436
LEU A 295
CYH A 362
ILE A 421
 None
 1.15A 3h52B-3vf1A:
undetectable		 3h52B-3vf1A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.72A 3hiiA-3vf1A:
undetectable		 3hiiA-3vf1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 HIS A 378
HIS A 373
HIS A 556
 FE2  A 701 (-3.3A)
FE2  A 701 (-3.4A)
FE2  A 701 (-3.3A)
 0.71A 3hiiB-3vf1A:
undetectable		 3hiiB-3vf1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 GLU A  63
ASP A  29
ASP A 126
 None
 0.74A 3jb2A-3vf1A:
undetectable		 3jb2A-3vf1A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASN A 413
GLY A 416
MET A 442
LEU A 158
ILE A 409
 None
 1.19A 3mneA-3vf1A:
undetectable		 3mneA-3vf1A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASN A 413
GLY A 416
VAL A 439
MET A 442
LEU A 158
 None
 1.35A 3mnoA-3vf1A:
undetectable		 3mnoA-3vf1A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ASN A 413
GLY A 416
VAL A 439
MET A 442
LEU A 158
 None
 1.34A 3mnpA-3vf1A:
undetectable		 3mnpA-3vf1A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 9 TYR A   3
ILE A  64
ILE A  67
VAL A  61
THR A  33
 None
 1.44A 3p4wA-3vf1A:
2.1		 3p4wA-3vf1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 VAL A 483
ILE A 491
MET A 640
PHE A 643
ILE A 484
 None
 1.03A 3qfxA-3vf1A:
undetectable		 3qfxA-3vf1A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 VAL A 483
ILE A 491
MET A 640
PHE A 643
ILE A 484
 None
 1.06A 3qfxB-3vf1A:
undetectable		 3qfxB-3vf1A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 ASP A 291
LEU A 314
ALA A 363
LEU A 295
 None
 1.08A 3rozA-3vf1A:
undetectable		 3rozA-3vf1A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 9 CYH A 554
HIS A 405
PHE A 643
ILE A 650
 None
 1.34A 4jvlA-3vf1A:
undetectable		 4jvlA-3vf1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 ALA A 641
PHE A 643
LYS A 644
LEU A 623
ILE A 484
 None
 1.04A 4kjjA-3vf1A:
undetectable		 4kjjA-3vf1A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 PHE A 535
THR A 406
LEU A 515
 None
 0.70A 4qztA-3vf1A:
undetectable		 4qztA-3vf1A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 6 LEU A 121
ASP A 505
LEU A 392
ILE A 491
 None
 1.08A 4y4dA-3vf1A:
undetectable		 4y4dA-3vf1A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 5 ALA A 164
ARG A 417
ALA A 411
GLU A 382
 None
 1.25A 5a06C-3vf1A:
undetectable
5a06D-3vf1A:
undetectable		 5a06C-3vf1A:
17.20
5a06D-3vf1A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		5 / 12 GLU A 279
LEU A 257
MET A 267
ASN A 265
ALA A 329
 None
 1.23A 5kc4A-3vf1A:
1.2		 5kc4A-3vf1A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		3 / 3 SER A 553
HIS A 405
TYR A 626
 None
 0.92A 5y2tA-3vf1A:
undetectable		 5y2tA-3vf1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3vf1 11R-LIPOXYGENASE
(Gersemia
fruticosa) 		4 / 5 ASN A 572
VAL A 609
LEU A 613
SER A 246
 None
 1.26A 6a7pA-3vf1A:
3.8		 6a7pA-3vf1A:
22.07