SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 6 VAL H  37
LEU H  48
PHE H  63
MET H  82
 None
 1.07A 1x8vA-3vfgH:
undetectable		 1x8vA-3vfgH:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR H  32
ASP H 101
HIS H  98
 None
 0.93A 3e23A-3vfgH:
undetectable		 3e23A-3vfgH:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H  87
GLU H 148
HIS H 199
 None
 0.81A 3g1uB-3vfgH:
undetectable		 3g1uB-3vfgH:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 8 TYR H  90
ASP H  85
PHE H  63
LEU H  48
 None
 0.94A 4f8hA-3vfgH:
3.5
4f8hB-3vfgH:
undetectable		 4f8hA-3vfgH:
19.50
4f8hB-3vfgH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 8 TYR H  90
ASP H  85
PHE H  63
LEU H  48
 None
 0.96A 4f8hB-3vfgH:
undetectable
4f8hC-3vfgH:
undetectable		 4f8hB-3vfgH:
19.50
4f8hC-3vfgH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 8 TYR H  90
ASP H  85
PHE H  63
LEU H  48
 None
 0.93A 4f8hC-3vfgH:
undetectable
4f8hD-3vfgH:
undetectable		 4f8hC-3vfgH:
19.50
4f8hD-3vfgH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 8 TYR H  90
ASP H  85
PHE H  63
LEU H  48
 None
 0.94A 4f8hD-3vfgH:
undetectable
4f8hE-3vfgH:
undetectable		 4f8hD-3vfgH:
19.50
4f8hE-3vfgH:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3vfg 3F8 HEAVY CHAIN
(Mus
musculus) 		4 / 8 PHE H  63
LEU H  48
TYR H  90
ASP H  85
 None
 0.95A 4f8hA-3vfgH:
3.5
4f8hE-3vfgH:
undetectable		 4f8hA-3vfgH:
19.50
4f8hE-3vfgH:
19.50