SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3vg8 HYPOTHETICAL PROTEIN
TTHB210
(Thermus
thermophilus) 		3 / 3 LYS G  52
LYS G  53
PRO G  50
 None
 1.08A 4dv1L-3vg8G:
undetectable		 4dv1L-3vg8G:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3vg8 HYPOTHETICAL PROTEIN
TTHB210
(Thermus
thermophilus) 		3 / 3 HIS G  87
GLY G  17
ILE G  15
 None
 0.59A 4k50A-3vg8G:
undetectable		 4k50A-3vg8G:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3vg8 HYPOTHETICAL PROTEIN
TTHB210
(Thermus
thermophilus) 		3 / 3 HIS G  87
GLY G  17
ILE G  15
 None
 0.58A 4k50I-3vg8G:
undetectable		 4k50I-3vg8G:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3vg8 HYPOTHETICAL PROTEIN
TTHB210
(Thermus
thermophilus) 		5 / 12 GLY G  17
LEU G  99
PHE G  47
GLY G  64
LEU G  34
 None
 1.15A 4ze1A-3vg8G:
undetectable		 4ze1A-3vg8G:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3vg8 HYPOTHETICAL PROTEIN
TTHB210
(Thermus
thermophilus) 		4 / 6 PRO G  12
LEU G  34
PHE G  33
LEU G  18
 None
 1.21A 5tl8A-3vg8G:
undetectable		 5tl8A-3vg8G:
14.81