SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vgf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 7 SER A 396
SER A 533
TYR A 556
LEU A 530
 None
 1.10A 1ibgL-3vgfA:
5.4		 1ibgL-3vgfA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 TRP A 150
GLY A 216
ALA A 253
GLU A 283
ASP A 377
 None
None
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-2.7A)
 0.99A 1kxhA-3vgfA:
21.2		 1kxhA-3vgfA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 6 ASP A 470
ILE A 389
GLU A 418
ARG A 394
 None
 0.97A 1mt1A-3vgfA:
undetectable
1mt1F-3vgfA:
undetectable		 1mt1A-3vgfA:
6.83
1mt1F-3vgfA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 6 ILE A 389
GLU A 418
ARG A 394
ASP A 470
 None
 0.92A 1mt1B-3vgfA:
undetectable
1mt1C-3vgfA:
undetectable		 1mt1B-3vgfA:
10.91
1mt1C-3vgfA:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 10 VAL A 188
ILE A 185
GLY A 248
ILE A 302
LEU A 251
 None
 1.12A 1z11C-3vgfA:
undetectable		 1z11C-3vgfA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 11 TYR A 105
GLY A 416
GLY A 420
ILE A 107
PHE A 112
 None
 1.50A 2dr2A-3vgfA:
undetectable		 2dr2A-3vgfA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		3 / 3 LYS A  57
TYR A 199
PRO A  67
 None
 1.13A 2j9cC-3vgfA:
undetectable		 2j9cC-3vgfA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 8 TYR A 397
ILE A 473
GLY A 420
ARG A 387
LEU A 465
 None
 1.16A 2vctA-3vgfA:
undetectable		 2vctA-3vgfA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 8 TYR A 397
ILE A 473
GLY A 420
ARG A 387
LEU A 465
 None
 1.19A 2vctB-3vgfA:
undetectable		 2vctB-3vgfA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 8 TYR A 397
ILE A 473
GLY A 420
ARG A 387
LEU A 465
 None
 1.16A 2vctC-3vgfA:
undetectable		 2vctC-3vgfA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 7 TYR A 397
ILE A 473
GLY A 420
ARG A 387
LEU A 465
 None
 1.19A 2vctD-3vgfA:
undetectable		 2vctD-3vgfA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		3 / 3 HIS A 108
MET A 415
MET A 139
 None
 1.13A 2vj1A-3vgfA:
undetectable		 2vj1A-3vgfA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 5 VAL A 361
VAL A 307
ASP A 309
SER A 338
 None
 1.29A 2x45C-3vgfA:
undetectable		 2x45C-3vgfA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.72A 3aicA-3vgfA:
2.1		 3aicA-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.76A 3aicB-3vgfA:
5.5		 3aicB-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		6 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
TYR A 152
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
GLC  A 604 ( 3.5A)
 0.71A 3aicC-3vgfA:
5.3		 3aicC-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.79A 3aicD-3vgfA:
5.4		 3aicD-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.79A 3aicE-3vgfA:
4.7		 3aicE-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.75A 3aicF-3vgfA:
7.5		 3aicF-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.72A 3aicG-3vgfA:
7.6		 3aicG-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ARG A 250
ALA A 253
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.1A)
GLC  A 604 (-4.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.81A 3aicH-3vgfA:
5.4		 3aicH-3vgfA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_B_SPMB502_1
(SPERMIDINE SYNTHASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 ASP A 453
ASP A 430
GLN A 455
GLU A 196
ILE A 437
 None
 1.22A 3b7pB-3vgfA:
undetectable		 3b7pB-3vgfA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 480
LEU A 487
SER A 475
PHE A 476
SER A 513
 None
 1.08A 3kk6A-3vgfA:
undetectable		 3kk6A-3vgfA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A 480
LEU A 487
SER A 475
PHE A 476
SER A 513
 None
 1.13A 3kk6B-3vgfA:
undetectable		 3kk6B-3vgfA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		3 / 3 GLY A 146
ASP A 430
ASP A 456
 None
 0.45A 3ou7C-3vgfA:
undetectable		 3ou7C-3vgfA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 VAL A  11
ASN A  48
TYR A  58
ILE A  45
TYR A  33
 None
 1.44A 3q5pA-3vgfA:
undetectable		 3q5pA-3vgfA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 7 ASN A 198
GLN A  20
TYR A  58
TYR A 156
 None
 1.27A 3ugrA-3vgfA:
8.5		 3ugrA-3vgfA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 10 LYS A 231
ILE A 233
HIS A 264
ILE A 265
ASP A 259
 None
 1.26A 4dtaA-3vgfA:
2.4		 4dtaA-3vgfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 11 HIS A 108
PHE A 144
GLY A 165
GLY A 166
TYR A  73
 None
 1.27A 4fglA-3vgfA:
undetectable
4fglB-3vgfA:
undetectable		 4fglA-3vgfA:
17.96
4fglB-3vgfA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 6 ASN A 375
GLU A 283
GLU A 106
GLU A 137
 None
GLC  A 604 (-2.6A)
None
None
 1.32A 4mi4A-3vgfA:
undetectable		 4mi4A-3vgfA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 11 ILE A 107
LEU A 125
LEU A 182
ALA A 177
LEU A 173
 None
 1.09A 4p65E-3vgfA:
undetectable
4p65F-3vgfA:
undetectable
4p65J-3vgfA:
undetectable
4p65L-3vgfA:
undetectable		 4p65E-3vgfA:
2.72
4p65F-3vgfA:
4.51
4p65J-3vgfA:
4.51
4p65L-3vgfA:
4.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 116
LEU A 465
MET A 415
ILE A 141
PHE A 118
 GOL  A1101 (-3.7A)
None
None
None
None
 1.31A 4p6xG-3vgfA:
undetectable		 4p6xG-3vgfA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A 116
LEU A 465
MET A 415
ILE A 141
PHE A 118
 GOL  A1101 (-3.7A)
None
None
None
None
 1.29A 4p6xI-3vgfA:
undetectable		 4p6xI-3vgfA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 6 ARG A 353
ASP A 285
VAL A 344
ASP A 309
 None
 1.39A 4xqeA-3vgfA:
undetectable		 4xqeA-3vgfA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 6 ARG A 353
ASP A 285
VAL A 344
ASP A 309
 None
 1.39A 4xqeB-3vgfA:
undetectable		 4xqeB-3vgfA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 TRP A 215
ARG A 250
GLU A 283
HIS A 376
ASP A 377
 GLC  A 604 (-3.3A)
GLC  A 604 (-3.1A)
GLC  A 604 (-2.6A)
GLC  A 604 (-4.0A)
GLC  A 604 (-2.7A)
 0.59A 5csyB-3vgfA:
18.0		 5csyB-3vgfA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 7 VAL A 246
ILE A 138
ASN A 191
PHE A 249
 None
None
GLC  A 604 ( 4.5A)
None
 0.89A 5hieC-3vgfA:
undetectable		 5hieC-3vgfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 4 ARG A 387
ILE A 389
TYR A 397
ILE A 473
 None
 1.24A 5odhG-3vgfA:
undetectable		 5odhG-3vgfA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 8 ASN A 423
PRO A 424
GLU A 386
TYR A 397
 None
 1.24A 5oh1C-3vgfA:
undetectable		 5oh1C-3vgfA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		4 / 7 LEU A 203
TYR A 199
PRO A  69
LEU A  60
 None
 1.03A 5t7bA-3vgfA:
1.6		 5t7bA-3vgfA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 VAL A 160
VAL A 273
PHE A 170
ILE A 279
PHE A 249
 None
 1.45A 6becA-3vgfA:
undetectable
6becB-3vgfA:
undetectable
6becC-3vgfA:
undetectable		 6becA-3vgfA:
22.27
6becB-3vgfA:
22.27
6becC-3vgfA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3vgf MALTO-OLIGOSYLTREHAL
OSE TREHALOHYDROLASE
(Sulfolobus
solfataricus) 		5 / 12 TYR A  56
LEU A  32
GLY A  31
VAL A  11
VAL A  50
 None
 1.32A 6bxlB-3vgfA:
undetectable		 6bxlB-3vgfA:
21.13