SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		3 / 3 GLU A 123
ALA A 125
SER A 119
 None
 0.62A 1errB-3vgsA:
undetectable		 1errB-3vgsA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		4 / 6 ILE A 103
ARG A  87
THR A   6
LEU A  77
 None
 1.01A 3ag1N-3vgsA:
undetectable
3ag1W-3vgsA:
undetectable		 3ag1N-3vgsA:
13.81
3ag1W-3vgsA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		5 / 12 ALA A 115
ILE A  10
SER A 110
GLU A  97
ALA A  92
 None
 1.24A 3axtA-3vgsA:
undetectable		 3axtA-3vgsA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		5 / 10 ILE A 103
ASP A 106
VAL A 116
ILE A  10
SER A  25
 None
 1.40A 3kpbD-3vgsA:
undetectable		 3kpbD-3vgsA:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		4 / 6 HIS A 117
GLU A 128
ASP A 120
SER A 124
 None
 1.10A 4apjA-3vgsA:
undetectable
4apjP-3vgsA:
undetectable		 4apjA-3vgsA:
14.26
4apjP-3vgsA:
36.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		4 / 7 ASN A  86
ALA A  84
GLU A  80
LEU A  77
 None
 0.97A 6ci6A-3vgsA:
undetectable		 6ci6A-3vgsA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3vgs NUCLEOSIDE
DIPHOSPHATE KINASE
(Halomonas
sp.
#593) 		4 / 7 ILE A 103
ARG A  87
THR A   6
LEU A  77
 None
 0.95A 6nmfA-3vgsA:
undetectable
6nmfJ-3vgsA:
undetectable		 6nmfA-3vgsA:
13.81
6nmfJ-3vgsA:
16.91