SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 8 THR A 100
GLY A 172
ALA A 115
ILE A 174
 None
 0.70A 1c9sI-3vh0A:
undetectable
1c9sJ-3vh0A:
undetectable		 1c9sI-3vh0A:
12.50
1c9sJ-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 8 GLY A 172
ALA A 115
ILE A 174
THR A 100
 None
 0.72A 1c9sU-3vh0A:
undetectable
1c9sV-3vh0A:
undetectable		 1c9sU-3vh0A:
12.50
1c9sV-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 7 GLY A 172
ALA A 115
ILE A 174
THR A 100
 None
 0.72A 1gtnA-3vh0A:
undetectable
1gtnK-3vh0A:
undetectable		 1gtnA-3vh0A:
12.50
1gtnK-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 8 THR A 100
GLY A 172
ALA A 115
ILE A 174
 None
 0.72A 1gtnE-3vh0A:
undetectable
1gtnF-3vh0A:
undetectable		 1gtnE-3vh0A:
12.50
1gtnF-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 8 THR A 100
GLY A 172
ALA A 115
ILE A 174
 None
 0.70A 1gtnI-3vh0A:
undetectable
1gtnJ-3vh0A:
undetectable		 1gtnI-3vh0A:
12.50
1gtnJ-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 8 GLY A 172
ALA A 115
ILE A 174
THR A 100
 None
 0.68A 1utdI-3vh0A:
undetectable
1utdJ-3vh0A:
undetectable		 1utdI-3vh0A:
12.50
1utdJ-3vh0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 6 ASN A  53
TYR A 329
TYR A  48
LEU A  55
 None
 1.40A 4f8yA-3vh0A:
undetectable
4f8yB-3vh0A:
undetectable		 4f8yA-3vh0A:
20.67
4f8yB-3vh0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		5 / 12 ALA A  58
ALA A 115
ILE A 116
ASN A 110
GLY A  69
 None
 1.13A 4r38A-3vh0A:
undetectable		 4r38A-3vh0A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		5 / 12 ALA A  58
ALA A 115
ILE A 116
ASN A 110
GLY A  69
 None
 1.09A 4r38B-3vh0A:
undetectable		 4r38B-3vh0A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		5 / 12 ALA A  58
ALA A 115
ILE A 116
ASN A 110
GLY A  69
 None
 1.11A 4r38C-3vh0A:
undetectable		 4r38C-3vh0A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		5 / 12 ALA A  58
ALA A 115
ILE A 116
ASN A 110
GLY A  69
 None
 1.10A 4r38D-3vh0A:
undetectable		 4r38D-3vh0A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 6 ASP A  66
TYR A  44
TYR A  72
LEU A  57
 None
 1.31A 5bmvB-3vh0A:
undetectable		 5bmvB-3vh0A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))		 3vh0 UNCHARACTERIZED
PROTEIN YNCE
(Escherichia
coli) 		4 / 5 ASP A 239
ARG A 244
ARG A 242
LEU A 353
 None
 1.30A 5tuiB-3vh0A:
undetectable		 5tuiB-3vh0A:
23.26