SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		4 / 8 TYR A1872
ASN A1917
ARG A1893
PHE A1941
 None
 1.14A 2fl5E-3vhlA:
undetectable
2fl5F-3vhlA:
undetectable		 2fl5E-3vhlA:
19.24
2fl5F-3vhlA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		4 / 4 LEU A1991
PRO A1990
LEU A2058
ARG A2055
 None
 1.27A 2hrcA-3vhlA:
undetectable		 2hrcA-3vhlA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		5 / 12 LEU A1830
GLY A1832
GLY A1835
ILE A1866
SER A1827
 None
 1.06A 3nk7A-3vhlA:
undetectable		 3nk7A-3vhlA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		4 / 8 TYR A1863
ILE A1846
ILE A1864
VAL A1852
 None
 0.85A 3p4wC-3vhlA:
2.9		 3p4wC-3vhlA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		4 / 7 THR A1897
TYR A1896
THR A1867
SER A1849
 None
 1.34A 5b6iA-3vhlA:
undetectable		 5b6iA-3vhlA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 3vhl DEDICATOR OF
CYTOKINESIS PROTEIN
8
(Mus
musculus) 		4 / 6 GLU A1939
PHE A1894
THR A1922
PHE A1941
 None
 1.39A 5lrbA-3vhlA:
undetectable		 5lrbA-3vhlA:
15.28