SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vi1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 239
LEU A 250
VAL A 326
GLY A 325
ALA A 323
 None
 1.22A 1e7aA-3vi1A:
undetectable		 1e7aA-3vi1A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 239
LEU A 250
VAL A 326
GLY A 325
ALA A 323
 None
 1.15A 1e7bA-3vi1A:
1.0		 1e7bA-3vi1A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 173
HIS A 176
GLU A 177
HIS A 180
TYR A 216
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
None
 0.56A 1j36A-3vi1A:
3.2		 1j36A-3vi1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 173
HIS A 176
GLU A 177
HIS A 180
TYR A 216
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
None
 0.56A 1j36B-3vi1A:
3.2		 1j36B-3vi1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 186
LEU A  40
HIS A 180
LEU A 139
PRO A 140
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.46A 1mjqA-3vi1A:
undetectable
1mjqB-3vi1A:
undetectable		 1mjqA-3vi1A:
11.55
1mjqB-3vi1A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A 186
LEU A  40
HIS A 180
LEU A 139
PRO A 140
 ZN  A 500 (-3.2A)
None
ZN  A 500 (-3.3A)
None
None
 1.47A 1mjqG-3vi1A:
undetectable
1mjqH-3vi1A:
undetectable		 1mjqG-3vi1A:
11.55
1mjqH-3vi1A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 349
GLY A 360
GLY A 361
LEU A 362
LEU A 305
 None
CA  A 507 (-4.4A)
CA  A 506 (-4.3A)
None
None
 0.86A 1mx1D-3vi1A:
undetectable		 1mx1D-3vi1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 193
GLU A 194
GLY A 195
TYR A 158
ASN A 161
 None
 1.26A 1n2xA-3vi1A:
undetectable		 1n2xA-3vi1A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 1os2A-3vi1A:
13.6		 1os2A-3vi1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 1os2D-3vi1A:
13.6		 1os2D-3vi1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 279
VAL A 313
GLY A 314
ASP A 293
 None
 0.77A 1p2yA-3vi1A:
undetectable		 1p2yA-3vi1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 10 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.37A 1r55A-3vi1A:
7.0		 1r55A-3vi1A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 279
VAL A 313
GLY A 314
ASP A 293
 None
 0.76A 1t88A-3vi1A:
undetectable		 1t88A-3vi1A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.25A 1uttA-3vi1A:
13.4		 1uttA-3vi1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.21A 1utzA-3vi1A:
13.2		 1utzA-3vi1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 1utzB-3vi1A:
13.2		 1utzB-3vi1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.21A 1y93A-3vi1A:
13.1		 1y93A-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 279
VAL A 313
GLY A 314
ASP A 293
 None
 0.82A 2a1oA-3vi1A:
undetectable		 2a1oA-3vi1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 135
HIS A 176
GLU A 177
HIS A 180
TYR A 216
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
None
 0.44A 2c6nA-3vi1A:
3.1		 2c6nA-3vi1A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 ASN A  25
TYR A 211
SER A  29
 None
 0.87A 2gvcB-3vi1A:
undetectable		 2gvcB-3vi1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 ASN A  25
TYR A 211
SER A  29
 None
 0.85A 2gvcE-3vi1A:
undetectable		 2gvcE-3vi1A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.19A 2hu6A-3vi1A:
13.2		 2hu6A-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.36A 2jihA-3vi1A:
6.7		 2jihA-3vi1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 8 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.31A 2jihB-3vi1A:
7.4		 2jihB-3vi1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.15A 2ow9A-3vi1A:
13.5		 2ow9A-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.19A 2ow9B-3vi1A:
13.4		 2ow9B-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.16A 2ozrC-3vi1A:
13.5		 2ozrC-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.19A 2ozrD-3vi1A:
13.6		 2ozrD-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.28A 2ozrE-3vi1A:
13.3		 2ozrE-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 176
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.26A 2ozrF-3vi1A:
13.5		 2ozrF-3vi1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 381
ALA A 409
LEU A 417
ILE A 402
LEU A 443
 None
 1.28A 2zzaA-3vi1A:
undetectable		 2zzaA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 ILE A 381
ALA A 409
LEU A 417
ILE A 402
LEU A 443
 None
 1.31A 2zzaB-3vi1A:
undetectable		 2zzaB-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 393
ASP A 435
ASN A 458
 None
 0.73A 2zzmA-3vi1A:
undetectable		 2zzmA-3vi1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 184
GLY A 179
ILE A 178
SER A 104
THR A 107
 None
 1.28A 3bjwB-3vi1A:
undetectable		 3bjwB-3vi1A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 349
ASP A 365
ILE A 303
GLY A 360
 None
CA  A 506 ( 2.7A)
None
CA  A 507 (-4.4A)
 0.96A 3bufA-3vi1A:
undetectable		 3bufA-3vi1A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 358
ASP A 374
ILE A 303
GLY A 369
 None
CA  A 504 ( 2.5A)
None
CA  A 505 (-4.4A)
 0.94A 3bufA-3vi1A:
undetectable		 3bufA-3vi1A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.75A 3bvdA-3vi1A:
undetectable		 3bvdA-3vi1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 360
LEU A 305
SER A 384
LEU A 367
LEU A 392
 CA  A 507 (-4.4A)
None
None
None
None
 0.97A 3cjtC-3vi1A:
undetectable		 3cjtC-3vi1A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 340
ASP A 374
ASP A 467
ILE A 402
LEU A 459
 None
CA  A 504 ( 2.5A)
None
None
None
 1.23A 3eeoA-3vi1A:
undetectable		 3eeoA-3vi1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A 172
VAL A 213
ASP A 238
ILE A 239
VAL A 106
 None
 1.41A 3fi0A-3vi1A:
undetectable		 3fi0A-3vi1A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A 172
VAL A 213
ASP A 238
ILE A 239
VAL A 106
 None
 1.45A 3fi0D-3vi1A:
undetectable		 3fi0D-3vi1A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A 172
VAL A 213
ASP A 238
ILE A 239
VAL A 106
 None
 1.46A 3fi0H-3vi1A:
undetectable		 3fi0H-3vi1A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A 172
VAL A 213
ASP A 238
ILE A 239
VAL A 106
 None
 1.42A 3fi0M-3vi1A:
undetectable		 3fi0M-3vi1A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.24A 3hy7A-3vi1A:
7.3		 3hy7A-3vi1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A 173
HIS A 176
GLU A 177
HIS A 180
HIS A 186
 None
ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.26A 3hy7B-3vi1A:
7.7		 3hy7B-3vi1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.18A 3kecA-3vi1A:
13.5		 3kecA-3vi1A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 176
GLU A 177
HIS A 180
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
 0.18A 3kecB-3vi1A:
13.3		 3kecB-3vi1A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 3likA-3vi1A:
13.2		 3likA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 3lilA-3vi1A:
13.2		 3lilA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.23A 3ljgA-3vi1A:
13.2		 3ljgA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.20A 3lkaA-3vi1A:
13.1		 3lkaA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.75A 3s38A-3vi1A:
undetectable		 3s38A-3vi1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 186
HIS A 180
HIS A 176
 ZN  A 500 (-3.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.80A 3s3aA-3vi1A:
undetectable		 3s3aA-3vi1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 415
LEU A 404
ILE A 381
ILE A 445
TYR A 359
 None
 1.21A 4a79A-3vi1A:
undetectable		 4a79A-3vi1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 415
LEU A 404
ILE A 381
ILE A 445
TYR A 359
 None
 1.21A 4a79B-3vi1A:
undetectable		 4a79B-3vi1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 415
LEU A 404
ILE A 381
ILE A 445
TYR A 359
 None
 1.26A 4a7aA-3vi1A:
undetectable		 4a7aA-3vi1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.24A 4a7bA-3vi1A:
13.6		 4a7bA-3vi1A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 318
ASN A 319
VAL A 313
GLN A 301
PHE A  12
 None
 1.46A 4j4vA-3vi1A:
undetectable		 4j4vA-3vi1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_B_SVRB301_1
(NUCLEOCAPSID PROTEIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 318
ASN A 319
VAL A 313
GLN A 301
PHE A  12
 None
 1.47A 4j4vB-3vi1A:
0.0		 4j4vB-3vi1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 318
ASN A 319
VAL A 313
GLN A 301
PHE A  12
 None
 1.46A 4j4vD-3vi1A:
undetectable
4j4vE-3vi1A:
undetectable		 4j4vD-3vi1A:
19.31
4j4vE-3vi1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_E_SVRE301_1
(NUCLEOCAPSID PROTEIN)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 318
ASN A 319
VAL A 313
GLN A 301
PHE A  12
 None
 1.43A 4j4vA-3vi1A:
0.0
4j4vE-3vi1A:
0.0		 4j4vA-3vi1A:
19.31
4j4vE-3vi1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 379
VAL A 377
PHE A  12
ILE A 341
 None
 0.82A 4xv2B-3vi1A:
undetectable		 4xv2B-3vi1A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.19A 5n5jA-3vi1A:
13.1		 5n5jA-3vi1A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 176
GLU A 177
HIS A 180
HIS A 186
 ZN  A 500 (-3.2A)
ZN  A 500 ( 4.2A)
ZN  A 500 (-3.3A)
ZN  A 500 (-3.2A)
 0.16A 5n5kA-3vi1A:
12.8		 5n5kA-3vi1A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 235
ASP A 237
ALA A  36
LEU A  40
 None
 1.01A 5nwvA-3vi1A:
undetectable		 5nwvA-3vi1A:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 4 VAL A 348
LEU A 349
LEU A 340
ASP A 356
 None
None
None
CA  A 503 ( 2.5A)
 1.10A 5xv7A-3vi1A:
undetectable		 5xv7A-3vi1A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		5 / 7 GLY A 334
GLY A 333
GLY A 351
GLY A 369
GLY A 370
 CA  A 503 (-4.4A)
CA  A 503 ( 4.8A)
CA  A 503 (-4.3A)
CA  A 505 (-4.4A)
CA  A 504 (-4.1A)
 1.03A 6ag0A-3vi1A:
undetectable		 6ag0A-3vi1A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3vi1 ALKALINE
METALLOPROTEINASE
(Pseudomonas
aeruginosa) 		4 / 6 SER A  45
TYR A 246
GLN A  43
THR A 107
 None
 1.50A 6djzA-3vi1A:
undetectable		 6djzA-3vi1A:
18.34