SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_1 (WNT INHIBITORY FACTOR 1)	3vib	MTRR (Neisseria gonorrhoeae)	4 / 5	ILE A 28 PHE A 62 VAL A 163 PHE A 113	None	1.29A	2ygnA-3vibA: undetectable	2ygnA-3vibA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_F_ZPCF1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3vib	MTRR (Neisseria gonorrhoeae)	5 / 12	GLU A 182 PHE A 178 TYR A 24 TYR A 106 ILE A 65	None	1.41A	4a97F-3vibA: 3.1 4a97J-3vibA: undetectable	4a97F-3vibA: 20.87 4a97J-3vibA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	3vib	MTRR (Neisseria gonorrhoeae)	3 / 3	TYR A 106 SER A 101 TRP A 177	None	1.05A	5n8jB-3vibA: undetectable	5n8jB-3vibA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	3vib	MTRR (Neisseria gonorrhoeae)	3 / 3	TYR A 106 SER A 101 TRP A 177	None	0.99A	5n8jA-3vibA: undetectable	5n8jA-3vibA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	3vib	MTRR (Neisseria gonorrhoeae)	3 / 3	TYR A 106 SER A 101 TRP A 177	None	1.01A	5n8jD-3vibA: undetectable	5n8jD-3vibA: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCE_A_RITA602_2 (CYTOCHROME P450 3A4)	3vib	MTRR (Neisseria gonorrhoeae)	4 / 6	ARG A 208 PHE A 165 ILE A 140 THR A 141	None	1.03A	5vceA-3vibA: undetectable	5vceA-3vibA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_1 (CYTOCHROME P450 3A4)	3vib	MTRR (Neisseria gonorrhoeae)	5 / 12	ASP A 68 PHE A 62 PHE A 108 THR A 31 ALA A 19	None	1.21A	5vcgA-3vibA: undetectable	5vcgA-3vibA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C06_D_FI8D1404_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	3vib	MTRR (Neisseria gonorrhoeae)	3 / 3	ARG A 137 LYS A 167 ARG A 98	None PO4 A 211 ( 2.6A) None	1.27A	6c06D-3vibA: 3.5	6c06D-3vibA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGN_A_PCFA1179_1","WNT INHIBITORY FACTOR 1","3vib","MTRR","Neisseria gonorrhoeae",4,"ILE A  28;PHE A  62;VAL A 163;PHE A 113","None","1.29A","2ygnA-3vibA:undetectable","2ygnA-3vibA:20.09"],["4A97_F_ZPCF1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3vib","MTRR","Neisseria gonorrhoeae",5,"GLU A 182;PHE A 178;TYR A  24;TYR A 106;ILE A  65","None","1.41A","4a97F-3vibA:3.1;4a97J-3vibA:undetectable","4a97F-3vibA:20.87;4a97J-3vibA:20.87"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","3vib","MTRR","Neisseria gonorrhoeae",3,"TYR A 106;SER A 101;TRP A 177","None","1.05A","5n8jB-3vibA:undetectable","5n8jB-3vibA:23.56"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","3vib","MTRR","Neisseria gonorrhoeae",3,"TYR A 106;SER A 101;TRP A 177","None","0.99A","5n8jA-3vibA:undetectable","5n8jA-3vibA:23.56"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","3vib","MTRR","Neisseria gonorrhoeae",3,"TYR A 106;SER A 101;TRP A 177","None","1.01A","5n8jD-3vibA:undetectable","5n8jD-3vibA:23.56"],["5VCE_A_RITA602_2","CYTOCHROME P450 3A4","3vib","MTRR","Neisseria gonorrhoeae",4,"ARG A 208;PHE A 165;ILE A 140;THR A 141","None","1.03A","5vceA-3vibA:undetectable","5vceA-3vibA:17.19"],["5VCG_A_08YA602_1","CYTOCHROME P450 3A4","3vib","MTRR","Neisseria gonorrhoeae",5,"ASP A  68;PHE A  62;PHE A 108;THR A  31;ALA A  19","None","1.21A","5vcgA-3vibA:undetectable","5vcgA-3vibA:17.19"],["6C06_D_FI8D1404_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","3vib","MTRR","Neisseria gonorrhoeae",3,"ARG A 137;LYS A 167;ARG A  98","None;PO4 A 211 ( 2.6A);None","1.27A","6c06D-3vibA:3.5","6c06D-3vibA:undetectable"]]